Computed Tomography of Adrenal Metastases in Hepatocellular Carcinoma

1989 ◽  
Vol 30 (5) ◽  
pp. 550-552 ◽  
Author(s):  
K. Nakamura ◽  
Y. Sato ◽  
H. Nakata
Keyword(s):  
Computed Tomography ◽  
Hepatocellular Carcinoma ◽  
Tumor Necrosis ◽  
Adrenal Tumor ◽  
Central Area ◽  
Adrenal Metastasis ◽  
Low Density ◽  
Solid Mass ◽  
Common Site ◽  
Adrenal Metastases

Four patients with adrenal metastases from hepatocellular carcinoma (HCC) diagnosed with computed tomography are described. In three, the metastases showed a central area of low density due to tumor necrosis, irregular contrast enhancement, and a well-defined margin. They measured 8 cm or more in diameter. In one, the adrenal metastasis was at first a relatively small homogeneously solid mass, but later, when it grew larger, a central low density developed. Since the adrenal gland is the second most common site of metastasis from HCC at autopsy, a combination of an adrenal tumor and a liver tumor should suggest this possibility.

Computed Tomography of Adrenal Metastases in Hepatocellular Carcinoma

1989 ◽  
Vol 30 (5) ◽  
pp. 550-552 ◽  
Author(s):  
K. Nakamura ◽  
Y. Sato ◽  
Hajime Nakata
Keyword(s):  
Computed Tomography ◽  
Hepatocellular Carcinoma ◽  
Adrenal Metastases

scholarly journals Retroperitoneal Liposarcoma With Leiomyosarcomatous Differentiation

2014 ◽  
Vol 99 (1) ◽  
pp. 48-51 ◽  
Author(s):  
Masaki Suzuki ◽  
Minoru Fukuchi ◽  
Shinji Sakurai ◽  
Hiroshi Naitoh ◽  
Shinsuke Kiriyama ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Tumor Resection ◽  
Abdominal Distention ◽  
Low Density ◽  
Solid Mass ◽  
Retroperitoneal Liposarcoma ◽  
Old Japanese ◽  
Giant Tumor ◽  
History Of ◽  
Well Differentiated

Abstract We herein describe a 60-year-old Japanese man with a giant retroperitoneal liposarcoma undergoing leiomyosarcomatous differentiation. He was admitted to our hospital because of a 5-month history of dysphagia and abdominal distention. Abdominal computed tomography showed a giant tumor that occupied the entire retroperitoneal space. The majority of the mass was lipomatous and low density; both a heterogenous and solid mass were also present. A giant retroperitoneal liposarcoma was diagnosed, and tumor resection was performed. At surgery, the tumor was mostly isolated from the retroperitoneum and other organs. Histopathologically, the tumor comprised well-differentiated and dedifferentiated liposarcoma with heterologous differentiation of the leiomyosarcomatous components, which is a rare phenomenon in liposarcoma. The patient was alive 3 years after the first treatment, although he has had 3 local recurrences (approximately one recurrence yearly) and has been treated by repeated resection and radiotherapy.

scholarly journals Palliative Radiotherapy Provided Good Pain Relief for Painful Adrenal Metastasis

2021 ◽  
pp. 1266-1270
Author(s):  
Masashi Endo ◽  
Yukiko Fukuda ◽  
Kazunari Ogawa ◽  
Satoru Takahashi ◽  
Michiko Nakamura ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Abdominal Pain ◽  
Pain Relief ◽  
Adverse Effects ◽  
Adrenal Tumor ◽  
Palliative Radiotherapy ◽  
Adrenal Metastasis ◽  
Adrenal Metastases ◽  
Good Pain Relief ◽  
Strong Opioids

Adrenal metastases often occur in patients with metastasized lung cancer, but symptoms rarely develop. A 45-year-old man presented with right abdominal pain requiring strong opioids due to large right adrenal metastasis of lung adenocarcinoma. The tumor was 7.3 × 5.6 × 8.4 cm in size. He was treated with palliative radiotherapy (RT) up to 39 Gy in 13 fractions for this lesion without severe adverse effects. After RT, he had good pain relief, and opioids were no longer needed. Palliative RT for a large adrenal tumor can provide a good analgesic effect without relevant toxicity.

scholarly journals Survival After Adrenalectomy for Metastatic Hepatocellular Carcinoma: A 25-year Institutional Experience

2020 ◽  
Author(s):  
JI. Staubitz ◽  
M. Hoppe-Lotichius ◽  
J. Baumgart ◽  
J. Mittler ◽  
H. Lang ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Liver Transplantation ◽  
Overall Survival ◽  
Medical Center ◽  
Adrenal Metastasis ◽  
Adrenal Metastases ◽  
Local Ablation ◽  
Transplantation Surgery ◽  
Institutional Experience ◽  
The University

Abstract Background Extrahepatic manifestation of hepatocellular carcinoma (HCC) is rare and primarily affects lung, lymph nodes and bone. Metastases to the adrenal glands are relatively infrequent. This 25-year institutional experience aimed for an analysis of factors influencing survival in patients undergoing surgery for HCC adrenal metastasis. Methods A retrospective analysis of the institutional database of the Clinic for General-, Visceral- and Transplantation Surgery of the University Medical Center Mainz, Germany, was performed. Patients who underwent surgery for HCC adrenal metastases from January 1995 to June 2020 were included. Pre-, peri- and postoperative factors with potential influence on survival were assessed. Results In 16 patients (14 males, two females), one bilateral and 15 unilateral adrenalectomies were performed (13 metachronous, three synchronous). Thirteen operations were carried out via laparotomy, and three adrenalectomies were minimally invasive (two laparoscopic, one retroperitoneoscopic). Median overall survival (after HCC diagnosis) was 35 months, range: 5–198. Median post-resection survival (after adrenalectomy) was 15 months, range: 0–75. Overall survival was longer in patients with the primary HCC treatment being liver transplantation (median 66 months) or liver resection (median 51 months), compared to only palliative intended treatment of the primary with chemotherapy (median 35 months) or local ablation (median 23 months). Conclusions Surgery is a feasible treatment option for patients with adrenal metastases originating from HCC. In patients who underwent adrenalectomy for HCC adrenal metastasis, overall survival was superior, if primary HCC treatment was potentially curative (liver transplantation or resection).

scholarly journals Hepatocellular carcinoma with extrahepatic adrenal metastasis: an atypical case report

2021 ◽  
Vol 7 (7) ◽  
pp. 360
Author(s):  
Diptajit Paul ◽  
Baljit Singh ◽  
Rakesh Dhankhar ◽  
Vivek Kaushal
Keyword(s):  
Public Health ◽  
Hepatocellular Carcinoma ◽  
Abdominal Pain ◽  
Kinase Inhibitor ◽  
Adrenal Metastasis ◽  
Common Site ◽  
Atypical Case ◽  
Good Patient ◽  
Good Patient Compliance ◽  
Upper Abdominal

<p class="abstract">Hepatocellular carcinoma with extrahepatic metastasis are a threat to public health worldwide. Lung, bones and abdominal lymph nodes are the major sites of metastasis from liver primary, adrenal metastasis being a less common site. Here we present an old male presented with upper abdominal pain diagnosed as advanced, unresectable hepatocellular carcinoma with right adrenal metastasis. Patient was treated with multi-kinase inhibitor sorafenib and outcome was acceptable with good patient compliance.</p>

Leberzellkarzinom – Radiofrequenzablation: Welches Bildgebungsverfahren ist effektiver?

2019 ◽  
Vol 24 (04) ◽  
pp. 163-164
Author(s):  
Cornelia Fietz
Keyword(s):  
Computed Tomography ◽  
Hepatocellular Carcinoma ◽  
Radiofrequency Ablation ◽  
Comparative Effectiveness ◽  
Percutaneous Radiofrequency Ablation ◽  
Ultrasound Guided ◽  
Medicare Patients ◽  
Us Dollar

Huo J et al. Comparative Effectiveness of Computed Tomography-Versus Ultrasound-Guided Percutaneous Radiofrequency Ablation Among Medicare Patients 65 Years of Age or Older With Hepatocellular Carcinoma. Value Health 2019; 22(3):284–292 Die Inzidenz des Leberzellkarzinoms hat sich in den letzen 20 Jahren mehr als verdoppelt. 2018 wurden in den USA mehr als 31 600 neue Fälle registriert, knapp die Hälfte dieser Patienten war älter als 65 Jahre. Die damit verbundenen jährlichen Kosten werden auf 455 Millionen US Dollar geschätzt. Für fortgeschrittene, inoperable Fälle steht die Radiofrequenzablation als Therapieoption zur Verfügung, die Ultraschall- oder Computertomographie-gestützt durchgeführt werden kann. Die Autoren vergleichen die Effektivität beider Bildgebungstechniken für das Verfahren.

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