scholarly journals Comparative study of pregnancy outcomes between day 3 embryo transfer and day 5 blastocyst transfer in patients with progesterone elevation

2013 ◽  
Vol 41 (4) ◽  
pp. 1318-1325 ◽  
Author(s):  
Rui-Rui Li ◽  
Yue-Zhi Dong ◽  
Yi-Hong Guo ◽  
Ying-Pu Sun ◽  
Ying-Chun Su ◽  
...  
Keyword(s):  
Comparative Study ◽  
Embryo Transfer ◽  
Pregnancy Outcomes ◽  
Blastocyst Transfer ◽  
Day 3 Embryo

scholarly journals Evaluation of Pregnancy Outcomes of Vitrified-Warmed Blastocyst Transfer before and after Endometrial Receptivity Analysis in Identical Patients with Recurrent Implantation Failure

2021 ◽  
pp. 1-7
Author(s):  
Yuta Kasahara ◽  
Tomoko Hashimoto ◽  
Ryo Yokomizo ◽  
Yuya Takeshige ◽  
Koki Yoshinaga ◽  
...  
Keyword(s):  
Pregnancy Rate ◽  
Embryo Transfer ◽  
Pregnancy Outcomes ◽  
Endometrial Receptivity ◽  
Pregnancy Rates ◽  
Blastocyst Transfer ◽  
Implantation Failure ◽  
Recurrent Implantation Failure ◽  
Clinical Value ◽  
Ongoing Pregnancy Rate

Background:The clinical value of personalized embryo transfer (pET) guided by the endometrial receptivity analysis (ERA) tests for recurrent implantation failure (RIF) cases is still unclear. The aim of this study is to clarify the efficacy of ERA leading to personalization of the day of embryo transfer (ET) in RIF patients. Methods: A retrospective study was performed for 94 patients with RIF who underwent ERA between July 2015 and December 2019. Pregnancy outcomes in a previous vitrified-warmed blastocyst transfer (previous VBT) and a personalized vitrified-warmed blastocyst transfer (pVBT) in identical patients were compared. The details of each pVBT were further analyzed between patients in a non-displaced group, which indicated “receptive” cases in ERA results and those who were in the displaced group, which indicated “non-receptive” cases. Results:When the pregnancy rate, both per patient and per transfer cycle, of previous VBT and pVBT were compared, a significant increase in pVBT was observed between the two methods (5.3% vs. 62.8%, 4.4% vs. 47.9%, respectively). The pregnancy rates, implantation rates, and clinical pregnancy rates of the first pVBT were significantly higher in the displaced group than the non-displaced group. The cumulative ongoing pregnancy rate of the displaced group tended to be higher compared to that of the non-displaced group in the first pVBT, although the difference was not statistically significant (51.0% vs. 31.1%, [Formula: see text] = 0.06). Conclusions:Our study demonstrates that pVBT guided by ERA tests may improve pregnancy outcomes in RIF patients whose window of implantation (WOI) is displaced, and its effect may be more pronounced at the first pVBT. The displacement of WOI may be considered to be one of the causes of RIF, and its adjustment may contribute to the improvement of pregnancy outcomes in RIF patients.

scholarly journals Day 3 embryo transfer with combined evaluation at the pronuclear and cleavage stages compares favourably with day 5 blastocyst transfer

2002 ◽  
Vol 17 (7) ◽  
pp. 1852-1855 ◽  
Author(s):  
L. Rienzi ◽  
F. Ubaldi ◽  
M. Iacobelli ◽  
S. Ferrero ◽  
M. G. Minasi ◽  
...  
Keyword(s):  
Embryo Transfer ◽  
Blastocyst Transfer ◽  
Cleavage Stages ◽  
Combined Evaluation ◽  
Day 3 Embryo

scholarly journals The effect of day 2 versus day 3 embryo transfer on early pregnancy outcomes in women with a low yield of fertilized oocytes

2018 ◽  
Vol 35 (5) ◽  
pp. 879-884
Author(s):  
C. R. Sacha ◽  
I. Dimitriadis ◽  
G. Christou ◽  
I. Souter ◽  
C. L. Bormann
Keyword(s):  
Embryo Transfer ◽  
Early Pregnancy ◽  
Pregnancy Outcomes ◽  
Day 3 Embryo

Embryo Transfer: A Retrospective Comparison of Day-5 Blastocyst Transfer Versus Day-3 Embryo Transfer

2000 ◽  
Vol 74 (3) ◽  
pp. S170-S171 ◽  
Author(s):  
M.R Freeman ◽  
K.G Howard ◽  
M.S Hinds ◽  
C.M Whitworth ◽  
G.A Weitzman ◽  
...  
Keyword(s):  
Embryo Transfer ◽  
Blastocyst Transfer ◽  
Retrospective Comparison ◽  
Day 3 Embryo

scholarly journals Comparison of Pregnancy Outcomes in Young Patients Following Fresh Versus Frozen Single Blastocyst Transfer: A Retrospective Study

2020 ◽  
Author(s):  
Yanhong Wu ◽  
Chang Liu ◽  
Chaochao Sheng ◽  
Haitao Xi ◽  
Yanghua Fu ◽  
...  
Keyword(s):  
Embryo Transfer ◽  
Pregnancy Outcomes ◽  
Young Patients ◽  
Blastocyst Transfer ◽  
Miscarriage Rate ◽  
Single Blastocyst Transfer ◽  
Group A ◽  
Group B ◽  
Cycle Group ◽  
Frozen Thawed Embryo Transfer

Abstract Background：Previous studies have shown that in young women, single blastocyst transfer can achieve satisfactory pregnancy results, but there are few studies on the difference between fresh and frozen-thawed single blastocyst transfer. In this retrospective analysis, the purpose of this study was to compare the pregnancy outcomes of young patients who received fresh or frozen-thawed single blastocyst transfer, so as to provide further clinical strategies for single blastocyst transfer.Methods: A retrospective analysis of patients aged ≤35 years old undergoing single blastocyst transfer was performed from January 2018 to December 2018 in the reproductive center of the Second Affiliated Hospital of Wenzhou Medical University. A total of 901 patients were involved and were divided into two groups according to the type of transfer cycle, 693 of which were in the fresh embryo transfer cycle (group A) and 208 of which were in the frozen-thawed embryo transfer cycle (group B). The laboratory and pregnancy outcomes were compared between the groups. Results：The number of oocytes retrieved in group B was significantly more than in group A ( P＜0.05). The early miscarriage rate in group B was higher than in group A, with significant difference(P＜0.05). There were no significant differences in other basic conditions and obstetric pregnancy outcomes between the two groups.Conclusions：Favorable pregnancy outcomes could be obtained in both fresh and frozen-thawed single blastocyst transfer in young patients without increasing the birth defect rate. For patients with risk factors of OHSS such as more oocyte retrieval, ovarian hyper-response, or risk factors of ectopic pregnancy such tubal infertility and the history of ectopic pregnancy, frozen-thawed single blastocyst transfer could be highly recommended in clinical practice. However, since the early miscarriage rate is higher in frozen-thawed embryo transfer group, further research is needed to figure out the cause and possible solutions.

scholarly journals Comparison of Pregnancy Outcomes Between Single-Morula Embryo Transfer and Single-Blastocyst Transfer in Fresh IVF/ICSI Cycles

2020 ◽  
Vol 26 ◽  
Author(s):  
Hui-na Zhang ◽  
Jun-zhao Zhao ◽  
Yi-lu Chen ◽  
Ying-fen Ying ◽  
Xiao-sheng Lu ◽  
...  
Keyword(s):  
Embryo Transfer ◽  
Pregnancy Outcomes ◽  
Blastocyst Transfer ◽  
Single Blastocyst Transfer

scholarly journals Does dysbiotic endometrium affect blastocyst implantation in IVF patients?

2019 ◽  
Vol 36 (12) ◽  
pp. 2471-2479 ◽  
Author(s):  
Tomoko Hashimoto ◽  
Koichi Kyono
Keyword(s):  
Embryo Transfer ◽  
Pregnancy Outcomes ◽  
Pathogenic Bacteria ◽  
Embryo Implantation ◽  
Pregnancy Rates ◽  
Species Level ◽  
Blastocyst Transfer ◽  
Microbiome Analysis ◽  
Genus Level ◽  
Blastocyst Implantation

Abstract Purpose To analyze the pregnancy outcomes of IVF patients presenting eubiotic or dysbiotic endometrium at the time of embryo transfer and to analyze what bacterial profiles are suitable for embryo implantation. Methods Ninety-nine IVF patients under 40 years old undergoing vitrified-warmed blastocyst transfer in HRT cycle had concurrent endometrial microbiome analysis. Samples from the endometrium were taken from the participants at the time of mock transfer; the bacterial profiles at genus level and percentage of lactobacilli in the endometrium of the patients were analyzed. Results Thirty-one cases (31.3%) had dysbiotic endometrium. The background profiles, pregnancy rates per transfer (52.9% vs 54.8%), and miscarriage rates (11.1% vs 5.9%) were comparable between patients with eubiotic or dysbiotic endometrium. Major bacterial genera other than Lactobacillus detected in the dysbiotic endometrium were Atopobium, Gardnerella, and Streptococcus. Some patients achieved ongoing pregnancies with 0% Lactobacillus in the endometrium. The endometrial bacterial profiles of pregnant cases with dysbiotic endometrium were comparable with those of non-pregnant cases. Conclusion Analyzing microbiota at the species-level resolution may be necessary for identifying the true pathogenic bacteria of the endometrium and avoiding over-intervention against non-Lactobacillus microbiota. Further studies are necessary for analyzing the mechanism of how the pathogenic bacteria affect embryo implantation.

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