Cleavage of Unfertilized Eggs after Repeated Administration of Human Chorionic Gonadotrophin to Hamsters

1997 ◽  
Vol 25 (4) ◽  
pp. 202-205 ◽  
Author(s):  
K Kanayama ◽  
H Osada ◽  
T Endo
Keyword(s):  
Repeated Administration ◽  
Chorionic Gonadotrophin ◽  
Human Chorionic Gonadotrophin ◽  
Induction Of Ovulation ◽  
Repeated Administrations ◽  
Repeated Doses

The proportions of unfertilized eggs in the oviducts, showing abnormal cleavage, were examined in hamsters given single or repeated doses of 30 IU human gonadotrophic hormone for the induction of ovulation. In control animals ( n = 7), 1.7% of the total ovulated eggs were morphologically abnormal unfertilized eggs showing cleavage. The proportions of unfertilized eggs that were abnormal in the groups of seven hamsters treated with one, two or three doses of the gonadotrophin were 20.4%, 19.4%, and 30.4%, respectively. The proportion of unfertilized eggs showing abnormal cleavage thus appeared to increase with repeated administrations of gonadotrophin.

scholarly journals Induction of ovulation in quarter horse mares through the use of deslorelin acetate and human chorionic gonadotrophin (hCG)

2011 ◽  
Vol 54 (3) ◽  
pp. 517-521 ◽  
Author(s):  
Tatiana Figueiredo ◽  
Roman Paiva ◽  
Luiz Ernandes Kozicki ◽  
Fernanda Kaercher ◽  
Romildo Romualdo Weiss ◽  
...  
Keyword(s):  
Chorionic Gonadotrophin ◽  
Human Chorionic Gonadotrophin ◽  
Induction Of Ovulation ◽  
Quarter Horse

CONCENTRATIONS OF CYCLIC AMP IN RABBIT OVARIAN TISSUE DURING THE PREOVULATORY PERIOD AND PSEUDOPREGNANCY AFTER INDUCTION OF OVULATION BY ADMINISTRATION OF HUMAN CHORIONIC GONADOTROPHIN

1975 ◽  
Vol 65 (1) ◽  
pp. 73-82 ◽  
Author(s):  
A. K. GOFF ◽  
PATRICIA W. MAJOR
Keyword(s):  
Cyclic Amp ◽  
Dose Response ◽  
Ovarian Tissue ◽  
Chorionic Gonadotrophin ◽  
Human Chorionic Gonadotrophin ◽  
Corpora Lutea ◽  
Response Relationship ◽  
Dose Response Relationship ◽  
Induction Of Ovulation ◽  
Relationship Of

SUMMARY Concentrations of cyclic AMP were measured in rabbit ovaries at various times after injection of an ovulatory dose of human chorionic gonadotrophin (HCG). A biphasic increase in cyclic AMP concentration occurred during the preovulatory period, with peaks 30 min and 3–4 h after HCG injection. Concentrations of cyclic AMP had returned to those observed in ovaries of control oestrous animals before the onset of ovulation 10–12 h after administration of HCG, and remained low throughout the period of pseudopregnancy. Concentrations of cyclic AMP in the newly formed and developing corpora lutea were similar to the concentrations observed in the remainder of the tissue during this period. No significant increase in cyclic AMP concentration was observed 7–9 days after initiation of ovulation. Concentrations of ATP were also investigated during the preovulatory period. The dose– response relationship of HCG to cyclic AMP production in oestrous rabbit ovaries was investigated.

THE INDUCTION OF OVULATION IN THE CHINCHILLA

1969 ◽  
Vol 43 (1) ◽  
pp. 55-NP ◽  
Author(s):  
B. J. WEIR
Keyword(s):  
Recovery Rate ◽  
Intraperitoneal Injection ◽  
Chorionic Gonadotrophin ◽  
Human Chorionic Gonadotrophin ◽  
Induction Of Ovulation

SUMMARY Forty-five adult chinchilla (Chinchilla laniger) were used to investigate the ovulatory response to pregnant mare serum (PMS) and human chorionic gonadotrophin (HCG) administered by intraperitoneal injection according to various regimes. Ovulation occurred (even during pregnancy) only when both PMS and HCG were given; 87·5% animals ovulated with a mean number of 3·7 ova, but only 26 out of the 119 ova were recovered. The range of ova ovulated per ovary was 1–7 and the range per animal was 1–12. The reasons for the low recovery rate of eggs and the general efficacy of the hormone regimes are discussed.

INDUCTION OF OVULATION WITH CLOMIPHENE AND HUMAN CHORIONIC GONADOTROPHIN IN WOMEN WITH HYPERPROLACTINAEMIC AMENORRHOEA

1978 ◽  
Vol 85 (9) ◽  
pp. 692-697 ◽  
Author(s):  
H. H. G. Mcgarrigle ◽  
S. Sarris ◽  
Valerie Little ◽  
Daphne Lawrence ◽  
Ewa Radwanska ◽  
...  
Keyword(s):  
Chorionic Gonadotrophin ◽  
Human Chorionic Gonadotrophin ◽  
Induction Of Ovulation

Twin Pregnancies Following Induction of Ovulation: A Literature Review

1982 ◽  
Vol 31 (3-4) ◽  
pp. 247-253 ◽  
Author(s):  
John A. Lamont
Keyword(s):  
Literature Review ◽  
Clomiphene Citrate ◽  
Vital Statistics ◽  
Chorionic Gonadotrophin ◽  
Human Chorionic Gonadotrophin ◽  
Multiple Pregnancies ◽  
Human Pituitary ◽  
True Incidence ◽  
Induction Of Ovulation ◽  
Human Menopausal Gonadotrophin

A literature review of the occurrence of multiple pregnancies associated with artificial induction of ovulation is reported. This report considers three treatment schedules: (1) clomiphene citrate; (2) human pituitary gonadotrophin with human chorionic gonadotrophin; and (3) human menopausal gonadotrophin with human chorionic gonadotrophin. The majority of the increase in twinning is related to hyperstimulation of the ovary by these medications, resulting in dizygotic twinning. The true incidence of twin pregnancy cannot be calculated because the vital statistics of all nations report live birth rates. Increased rates of fetal wastage, late abortion and prematurity associated with the occurrence of multiple pregnancies are overlooked by these statistics. The increased incidence of twinning appears to be related to the type and dosage of medication used, and the patient's underlying problem.

PROGESTERONE LEVELS AFTER INDUCTION OF OVULATION IN DIOESTROUS RATS

1980 ◽  
Vol 87 (1) ◽  
pp. 141-146 ◽  
Author(s):  
MARIKO SHIROTA ◽  
SHUJI SASAMOTO
Keyword(s):  
Single Injection ◽  
Secretory Activity ◽  
Chorionic Gonadotrophin ◽  
Human Chorionic Gonadotrophin ◽  
Corpora Lutea ◽  
Induction Of Ovulation ◽  
Normal Number ◽  
Lh Rh ◽  
Lh Releasing Hormone ◽  
Premature Ovulation

Maximal levels of progesterone in the plasma after premature ovulation induced by either the administration of human chorionic gonadotrophin (HCG) or LH-releasing hormone (LH-RH) to dioestrous (day 0) rats were observed from 33 to 45 h but decreased 3 h earlier than after spontaneous ovulation. This suggested an earlier decline in the secretory activity of corpora lutea formed from premature ovulations than that of corpora lutea formed during a normal oestrous cycle. The next spontaneous ovulation occurred 4 days (day 5) after premature ovulation induced by LH-RH on day 0. A single s.c. injection of 2·5 μg oestradiol-17β (OE2) at 10.00 h on day 2 to these animals advanced the next spontaneous ovulation by 1 day. A normal number of oocytes was shed, indicating that earlier secretion of oestrogen on day 2 had advanced the next spontaneous ovulation. A single injection of 2·5 μg OE2 to normal 4-day cyclic rats at metoestrus failed to advance the next ovulation. An earlier decline of progesterone levels in the plasma of rats after premature ovulation as compared with spontaneous ovulation may explain the greater effectiveness of oestrogen in the former group. The progesterone surge was observed during the period of premature ovulation in both HCG- and LH-RH-treated groups. This progesterone release in the periovulatory period may be responsible for the inhibition of gonadotrophin surges on the expected day of prooestrus (day 1).

INDUCTION OF OVULATION BY GONADOTROPHINS IN THE INDIAN FIVE-STRIPED PALM SQUIRREL FUNAMBULUS PENNANTI (WROUGHTON)

1967 ◽  
Vol 39 (3) ◽  
pp. 369-NP ◽  
Author(s):  
PUSHPA SETH ◽  
M. R. N. PRASAD
Keyword(s):  
Breeding Season ◽  
Reproductive Cycle ◽  
Single Injection ◽  
Chorionic Gonadotrophin ◽  
Human Chorionic Gonadotrophin ◽  
Follicular Growth ◽  
Induction Of Ovulation ◽  
Induced Ovulation ◽  
Follicular Maturation ◽  
Pregnant Mare Serum Gonadotrophin

SUMMARY Superovulation was induced in palm squirrels by the administration of gonadotrophins. The regimen of treatment effective in inducing ovulation was 60 i.u. pregnant mare serum gonadotrophin (PMS) administered in three doses of 20 i.u. on days 1, 4 and 7, followed by a single injection of 40 i.u. human chorionic gonadotrophin (HCG) on day 14. The same schedule of PMS and HCG administration induced ovulation in mature and immature squirrels both during the breeding season and the period of sexual quiescence. Ovulation did not occur in PMS-treated females if HCG was not administered. The period required for follicular growth before the follicles responded to the ovulatory stimulus of HCG was 13–14 days; the interval for follicular maturation leading to the release of the ovum was approximately 24 hr. Variations in the numbers of ova shed by different groups of females are related to the phase of the reproductive cycle and the age of the squirrels.

Sign in / Sign up

Export Citation Format

Share Document