Urinary diversion: Anatomo-physiological assumptions

1992 ◽  
Vol 59 (2) ◽  
pp. 9-15
Author(s):  
F. Di Tonno ◽  
M. De Antoni ◽  
V. Ruvolo ◽  
D. Lavelli

The basic anatomical and physiological conditions needed for preparation of a good functioning urinary reservoir are analyzed according to current literature and personal experience. Owing to the need for a schematic and concise exposition, the text has been subdivided under five headings: (I) Metabolic considerations: a) the segment used; b) the duration of contact between intestinal mucosa and urine; c) the size of the exposed intestinal surface. (II) Renal function. (Ill) Physical properties of the reservoir: a) contractility; b) configuration; c) accommodation; d) viscoelasticity. (IV) Carcinogenesis: a) statistical considerations; b) ethiopathogenesis. (V) Clinical consequences of the removal of a normally functioning intestinal segment.

2013 ◽  
Vol 60 (1) ◽  
pp. 53-60
Author(s):  
Z.M. Dzamic ◽  
B.M. Kajmakovic ◽  
T. Pejcic ◽  
B. Milkovic ◽  
M. Acimovic ◽  
...  

Ileal conduit as a form supravesical derivaton, is still one of most popular method of urinary diversion, in daily urological practice. Bearing in mind this fact, this type of diversion, rightfully so, is also called the "gold standard" in the derivation of urine. Considering the fact of unnatural route of elimination of urine from the upper urinary tract that occurs during creation of ileal conduit, it is reasonable to expect that, in time, this type of diversion lead to some degree of renal insufficiency. Some authors, this effect on renal function, attribute to specific type of ureterointestinal anastomosis during formation of ileal conduit1,2. A very important part of the surgical technique of creating ileal conduit is precisely a step of implantation ureters into the intestinal segment. The ultimate goal is to enable a more natural way of evacuation of urine from the upper urinary tract in terms of maintaining the quality of renal function. Numerous authors describes a quite number of techniques of ureteral implantation into the intestinal segment (Wallace A, Wallace B, Nesbit-Bricker, Le Duc ...)3,4. Each of these techniques has its own strengths and weaknesses, and the decision witch technique will be applied is still in the hand of urologist - operator, individually. Bearing in mind the fact of unnatural route of elimination of urine from the upper urinary tract that occurs during creation of ileal conduit, it is reasonable to expect that the renal function over the time will start to show signs of incipient or advanced failure 5,6,7,8. Objective: To determine the most appropriate type ureterointestinal anastomosis in forming ileal conduit, as a form of supravesical urinary diversion, to ensure adequate renal function postoperatively as an important parameter of quality of life. Methods and patients: This is a retrospective study, which covered a population of 193 patients treated at the Department of Urology, Clinical Center of Serbia, who underwent creation of ileal conduit as a form of urinary diversion. The study was conducted 2007. - 2011. Postoperative follow-up lasts up to 48 months. The assess of the level of renal insufficiency were analyzed by monitoring parameters which determine the degree of anemia, and biochemical parameters of renal function. We have investigated three techniques of insertion of the ureters into the ileal conduit, which are used in the daily practice (Wallace A, Wallace B, Nesbit-Bricker). Conclusion: Kidney failure occurs equally often in all patients who underwent urinary diversion by ileal conduit, ignoring the type of insertion of the ureters to the intestinal segment.


2003 ◽  
Vol 71 (3) ◽  
pp. 275-279 ◽  
Author(s):  
G. Mattioli ◽  
P. Buffa ◽  
M. Torre ◽  
C. Carlini ◽  
A. Pini Prato ◽  
...  

PEDIATRICS ◽  
1967 ◽  
Vol 40 (5) ◽  
pp. 816-821
Author(s):  
James M. Holland ◽  
Lowell R. King ◽  
Horst K. A. Schirmer ◽  
William Wallace Scott

High ileal diversion has been performed on 26 children with destroyed ureteral function in the authors' experience. Fifteen were azotemic when diverted. Renal function has improved or stabilized in 21 of the 23 patients (91%) who survived operation followed for as long as 8 years. Pyelographic appearance has improved or stabilized in 34 of 39 kidneys (87%) in these children. Ten patients were diverted more than 5 years ago. Renal function has improved or stabilized in all seven who are now alive. High ileal diversion has thus proved to be safe and reliable. Although azotemic children also can be salvaged, the authors advocate earlier high diversion of kidneys drained by badly dilated and poorly functioning ureters.


2020 ◽  
Vol 9 (7) ◽  
pp. 2191
Author(s):  
Massimiliano Creta ◽  
Ferdinando Fusco ◽  
Roberto La Rocca ◽  
Marco Capece ◽  
Giuseppe Celentano ◽  
...  

Deterioration of renal function has been reported after radical cystectomy (RC) with urinary diversion. We investigated renal function changes in elderly bladder cancer (BCa) patients who underwent RC with cutaneous ureterostomy (CU) urinary diversion. We performed a retrospective, observational study. BCa patients aged ≥75 with an American Society of Anesthesiologists (ASA) class greater than II were included. Glomerular filtration rate (GFR) was the main outcome measure. GFR values were recorded preoperatively, at discharge, at 6-month follow-up, and yearly up to 60 months. A total of 70 patients with a median age of 78.0 years were identified. Median preoperative GFR was 74.3 mL/min/1.73 m2 and declined significantly to 54.6 mL/min/1.73 m2 after 6 months (p < 0.001). A gradual GFR decline was observed thereafter, reaching a median value of 46.2 after 60 months. Preoperative GFR and acute kidney injury were significant predictors of fast deterioration of GFR and of 25% deterioration of GFR after 12 months. Elderly BCa patients with high comorbidity rates undergoing RC with CU should be carefully informed about the risk of GFR deterioration and the need for adequate monitoring.


1995 ◽  
Vol 62 (3) ◽  
pp. 489-492
Author(s):  
A. Trinchieri

Internai urinary diversions date back more than 100 years to when ureterosigmoidostomy was introduced by Simon. Urinary diversion to the rectum is a simple technique of continent urinary diversion but can cause troublesome complications such as electrolyte imbalance, pyelonephritis and renal function deterioration. Improvement of the techniques of internai urinary diversion have reduced the risk of such complications. When the urethra cannot be preserved, internai urinary diversion provides a viable alternative to external diversion.


1986 ◽  
Vol 250 (2) ◽  
pp. F294-F301 ◽  
Author(s):  
J. E. Robillard ◽  
K. T. Nakamura ◽  
G. F. DiBona

The role of renal nerves in mediating renal hemodynamics and renal function during normal physiological conditions and following moderate hypoxemia was studied in chronically catheterized fetal lambs (125-141 days of gestation) following unilateral renal denervation. Base-line values for renal blood flow (RBF), renal vascular resistance (RVR), glomerular filtration rate (GFR), urinary flow rate (UFR), urinary electrolyte (Na+, K+, and Cl-) excretion rate, and urine osmolality (Uosm) were similar in both intact and denervated kidneys. Hypoxemia was associated with a significant rise in mean arterial blood pressure and a significant decrease in heart rate. Hypoxemia produced a similar decrease in GFR and similar increases in urinary Na+ and Cl- excretion rates in both intact and denervated kidneys. However, the effect of hypoxemia on renal hemodynamics differed between intact and denervated kidneys. Hypoxemia produced a continuous and progressive decrease in RBF and increase in RVR in the intact kidney. On the other hand, renal denervation was associated with an early renal vasodilation and attenuated the reduction in RBF and the rise in RVR during hypoxemia; this early renal vasodilation was blunted following prostaglandin synthesis inhibition. Taken together, these results suggest that fetal renal denervation is not associated with significant changes in renal hemodynamics or renal function during normal physiological conditions but that renal denervation partially inhibited the renal vasoconstriction associated with fetal hypoxemia. Finally, it was found that endogenous prostaglandins counteract the renal vasoconstriction associated with fetal hypoxemia.


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