Autotransfusion in urology: Control study on 59 cases

1992 ◽  
Vol 59 (1_suppl) ◽  
pp. 73-75
Author(s):  
S. Spatafora ◽  
D. Lasagni ◽  
R. Baricchi ◽  
R. Rossi-Cesolari ◽  
C. Lusenti ◽  
...  
Keyword(s):  
Blood Transfusion ◽  
Autologous Blood ◽  
Performance Status ◽  
Hemoglobin Concentration ◽  
Control Group ◽  
Autologous Blood Transfusion ◽  
Homologous Blood ◽  
Significant Difference ◽  
Discharge From Hospital ◽  
Control Study

We studied the hematologic and clinical patterns of 59 patients undergoing urologic surgery who entered in a predeposit autologous blood transfusion program and of 59 controls to evaluate the feasibility and safety of the autotransfusional procedure in Urology. 174 units of autologous blood were donated (average 2.94 per pt.) with a high frequency of donation (2.6 days). No side effect or alteration of performance status was reported. We had a dramatic reduction of the need for homologous blood (2.21 units per pt.) without a significant difference of the average hemoglobin concentration between the two groups at discharge from hospital. Autotransfusion has significant advantages compared with conventional transfusion, reducing the complications correlated with homologous blood infusion as also our study demonstrated. Infact 1 post-transfusional hepatitis and 3 complications due to an alteration of coagulation were reported in the control group. The procedure resulted safe and feasible in most urologic operations that require almost two units of blood transfusion.

Acute Isovolaemic Haemodilution: The Best Option for Autologous Blood Transfusion in Africa?

1995 ◽  
Vol 25 (4) ◽  
pp. 152-155 ◽  
Author(s):  
Zacharia A Berege ◽  
Bart Jacobs ◽  
Michael R Matasha ◽  
Frank Mpelumbe ◽  
Ernestini Kimaro
Keyword(s):  
Blood Transfusion ◽  
Blood Loss ◽  
Autologous Blood ◽  
Autologous Blood Transfusion ◽  
Total Blood Volume ◽  
East African ◽  
Homologous Blood ◽  
Total Blood ◽  
Induction Of Anaesthesia ◽  
Donated Blood

The purpose of this study was to identify the best method of autologous blood transfusion to be applied in an East African hospital. One hundred and nine consecutive patients for whom major blood loss was anticipated were enrolled. Seventeen patients donated 1 unit of blood 3 days preoperatively and 92 underwent acute isovolaemic haemodilution prior to induction of anaesthesia. For the haemodiluted patients a 2:1 ratio of sterile pryogen-free saline to collected blood was used. One of the 16 patients from whom 2 units were withdrawn by haemodilution experienced hypovolaemia which was rapidly restored by additional transfusion of colloid. Of the patients who donated blood preoperatively only 23.5% were autotransfused compared to 98.9% of the haemodiluted patients. Of the latter 23.9% (22) had an intraoperative blood loss exceeding 15% of their total blood volume and 7.6% (7) lost more than 25%. Only one received homologous blood in addition. For hospitals with limited blood bank facilities and regular cancellation of surgery, the use of acute isovolaemic haemodilution is recommended. A 3:1 ratio of saline to blood is now advised when 1 unit is withdrawn and a part replacement with crystalloid when 2 units are collected.

scholarly journals Intraoperative red blood cell salvage and autologous transfusion during open radical retropubic prostatectomy: a cost–benefit analysis

2011 ◽  
Vol 93 (2) ◽  
pp. 157-161 ◽  
Author(s):  
Sarvpreet Ubee ◽  
Manal Kumar ◽  
Nallaswami Athmanathan ◽  
Gurpreet Singh ◽  
Sean Vesey
Keyword(s):  
Blood Transfusion ◽  
Autologous Blood ◽  
Radical Retropubic Prostatectomy ◽  
Autologous Blood Transfusion ◽  
Cell Saver ◽  
Cell Salvage ◽  
Homologous Blood ◽  
Retropubic Prostatectomy ◽  
Group A ◽  
Group B

INTRODUCTION Open radical retropubic prostatectomy (RRP) has an average blood loss of over 1,000ml. This has been reported even from high volume centres of excellence. 1 – 4 We have looked at the clinical and financial benefits of using intraoperative cell salvage (ICS) as a method of reducing the autologous blood transfusion requirements for our RRP patients. MATERIALS AND METHODS Group A comprised 25 consecutive patients who underwent RRP immediately prior to the acquisition of a cell saver machine. Group B consisted of the next 25 consecutive patients undergoing surgery using the Dideco Electa (Sorin Group, Italy) cell saver machine. Blood transfusion costs for both groups were calculated and compared. RESULTS The mean postoperative haemoglobin was similar in both groups (11.1gm/dl in Group A and 11.4gm/dl in Group B). All Group B patients received autologous blood (average 506ml, range: 103–1,023ml). In addition, 5 patients (20%) in Group B received a group total of 16 units (average 0.6 units) of homologous blood. For Group A the total cost of transfusing the 69 units of homologous blood was estimated as £9,315, based on a per blood unit cost of £135. This cost did not include consumables or nursing costs. CONCLUSIONS We found no evidence that autologous transfusions increased the risk of early biochemical relapse or of disease dissemination. ICS reduced our dependence on donated homologous blood.

scholarly journals Fresh Autologous Blood Transfusion and Platelet Counts after Cardiopulmonary Bypass Surgery

1982 ◽  
Vol 10 (4) ◽  
pp. 348-352 ◽  
Author(s):  
V. S. Iyer ◽  
W. J. Russell
Keyword(s):  
Platelet Count ◽  
Blood Transfusion ◽  
Blood Loss ◽  
Autologous Blood ◽  
Early Postoperative Period ◽  
Postoperative Blood Loss ◽  
Control Group ◽  
Substantial Part ◽  
Autologous Blood Transfusion ◽  
Platelet Counts

The effect of fresh autologous blood transfusion on platelet count and blood requirement in the early postoperative period is examined in a control group and in patients receiving early and late autologous replacement. Withdrawal of blood in the autologous groups appeared to enhance platelet numbers as the autologous groups had higher mean platelet counts than the control group immediately after bypass, in spite of having lower mean haematocrit. After bypass all groups showed a progressive rise in platelet count with time. A substantial part of the rise was explained by haemoconcentration resulting from fluid shifts but there was also an increase in the total circulating platelet numbers. There was no difference in postoperative blood loss between the three groups. Autologous blood replacement hastens the postoperative rise in platelet count but does not alter the postoperative blood loss.

scholarly journals Should Autologous Blood Transfusion be Rediscovered?

1980 ◽  
Vol 8 (2) ◽  
pp. 168-171 ◽  
Author(s):  
James P. Isbister ◽  
Richard Davis
Keyword(s):  
Blood Transfusion ◽  
Autologous Blood ◽  
Autologous Blood Transfusion ◽  
Homologous Blood ◽  
Homologous Blood Transfusion ◽  
Efficient Alternative

With a greater appreciation and understanding of reactions to homologous blood transfusion there has been a renewed interest in autologous blood transfusion. The techniques and indications for preoperative banked autologous blood, perioperative haemodilution and recycled salvaged autologous blood transfusion are described. When circumstances permit, autologous blood transfusion is a safe, economical and efficient alternative to homologous blood.

Autologous blood transfusion in prostatic surgery

1994 ◽  
Vol 61 (2) ◽  
pp. 107-110
Author(s):  
A.M. Soldà ◽  
G. Capponi ◽  
G. Correggi ◽  
T. Calcagno ◽  
M. Campagnoli ◽  
...  
Keyword(s):  
Radical Prostatectomy ◽  
Blood Transfusion ◽  
Autologous Blood ◽  
Autologous Blood Transfusion ◽  
Discharge From Hospital ◽  
Suprapubic Prostatectomy

Autotransfusion is becoming a more widely used technique as it avoids risks associated with homologous transfusions. The authors present results of a self-donation programme used for 1301 patients in prostatic surgery from 1982 to 1993. Selected patients made a blood pre-deposit of 350 to 450 ml prior to suprapubic prostatectomy, and two pre-deposits prior to radical prostatectomy. 93% of the patients did not require additional transfusions. 30% of the patients did not require any transfusion. The Hb value was satisfactory upon discharge from hospital (> 10 g/dl). The programme was successful in protecting the patients from infective and immunological risks associated with homologous transfusion.

scholarly journals Postoperative Autologous Reinfusion in Total Knee Replacement

2015 ◽  
Vol 2015 ◽  
pp. 1-6 ◽  
Author(s):  
A. Crescibene ◽  
F. Martire ◽  
P. Gigliotti ◽  
A. Rende ◽  
M. Candela
Keyword(s):  
Blood Transfusion ◽  
Total Knee Replacement ◽  
Knee Replacement ◽  
Knee Prosthesis ◽  
Autologous Blood ◽  
Control Group ◽  
Homologous Blood ◽  
Transfusion Therapy ◽  
Prosthesis Replacement ◽  
Total Knee

Surgeries for total knee replacement (TKR) are increasing and in this context there is a need to develop new protocols for management and use of blood transfusion therapy. Autologous blood reduces the need for allogeneic blood transfusion and the aim of the present study was to verify the safety and the clinical efficacy. An observational retrospective study has been conducted on 124 patients, undergoing cemented total knee prosthesis replacement. Observed population was stratified into two groups: the first group received reinfusion of autologous blood collected in the postoperative surgery and the second group did not receive autologous blood reinfusion. Analysis of data shows that patients undergoing autologous blood reinfusion received less homologous blood bags (10.6% versus 30%; p=0.08) and reduced days of hospitalization (7.88 ± 0.7 days versus 8.96 ± 2.47 days for the control group; p=0.03). Microbiological tests were negative in all postoperatively salvaged and reinfused units. Our results emphasize the effectiveness of this procedure and have the characteristics of simplicity, low cost (€97.53 versus €103.79; p<0.01), and easy reproducibility. Use of autologous drainage system postoperatively is a procedure that allows reducing transfusion of homologous blood bags in patients undergoing TKR.

Postoperative Inflammatory Response after Autologous and Allogeneic Blood Transfusion

1997 ◽  
Vol 87 (3) ◽  
pp. 511-516 ◽  
Author(s):  
Anders Avall ◽  
Monica Hyllner ◽  
Jan Peter Bengtson ◽  
Lars Carlsson ◽  
Anders Bengtsson
Keyword(s):  
Blood Transfusion ◽  
Autologous Blood ◽  
Plasma Concentrations ◽  
Allogeneic Blood Transfusion ◽  
Allogeneic Blood ◽  
Autologous Blood Transfusion ◽  
Blood Transfusions ◽  
Joint Replacement Surgery ◽  
Autologous Whole Blood ◽  
Significant Difference

Background Allogeneic blood transfusions cause immunosuppression. The aim of this study was to determine whether complement anaphylatoxins, cytokines, or both are released in the recipient, after blood transfusions in general, and after autologous blood transfusions in particular. Methods Thirty-one patients having total hip joint replacement surgery were randomized to receive either allogeneic red blood cells (n = 15) or predeposited autologous whole blood transfusion (n = 16). Plasma concentrations of the anaphylatoxins C3a and C5a, the terminal C5b-9 complement complex, and cytokines IL-6 and IL-8 in the recipients were repeatedly analyzed before, during, and after surgery. Results Significantly increased concentrations of IL-6 and IL-8 appeared in both groups, with a significantly greater increase in the autologous blood group. Patients in both groups developed a moderate but significant increase of C3a without a significant difference between them. C5a and terminal C5b-9 complement complex were not greatly changed. Conclusions The study showed a greater increase in cytokine concentration after autologous blood transfusion than after allogeneic blood transfusion. The lower response in the latter may result from transfusion-induced suppression of cellular immunity.

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