Acute Isovolaemic Haemodilution: The Best Option for Autologous Blood Transfusion in Africa?

1995 ◽  
Vol 25 (4) ◽  
pp. 152-155 ◽  
Author(s):  
Zacharia A Berege ◽  
Bart Jacobs ◽  
Michael R Matasha ◽  
Frank Mpelumbe ◽  
Ernestini Kimaro
Keyword(s):  
Blood Transfusion ◽  
Blood Loss ◽  
Autologous Blood ◽  
Autologous Blood Transfusion ◽  
Total Blood Volume ◽  
East African ◽  
Homologous Blood ◽  
Total Blood ◽  
Induction Of Anaesthesia ◽  
Donated Blood

The purpose of this study was to identify the best method of autologous blood transfusion to be applied in an East African hospital. One hundred and nine consecutive patients for whom major blood loss was anticipated were enrolled. Seventeen patients donated 1 unit of blood 3 days preoperatively and 92 underwent acute isovolaemic haemodilution prior to induction of anaesthesia. For the haemodiluted patients a 2:1 ratio of sterile pryogen-free saline to collected blood was used. One of the 16 patients from whom 2 units were withdrawn by haemodilution experienced hypovolaemia which was rapidly restored by additional transfusion of colloid. Of the patients who donated blood preoperatively only 23.5% were autotransfused compared to 98.9% of the haemodiluted patients. Of the latter 23.9% (22) had an intraoperative blood loss exceeding 15% of their total blood volume and 7.6% (7) lost more than 25%. Only one received homologous blood in addition. For hospitals with limited blood bank facilities and regular cancellation of surgery, the use of acute isovolaemic haemodilution is recommended. A 3:1 ratio of saline to blood is now advised when 1 unit is withdrawn and a part replacement with crystalloid when 2 units are collected.

Be your own donor: An insight into the technique of Autologous blood transfusion

2011 ◽  
Vol 3 (2) ◽  
pp. 28-30
Author(s):  
Rajendra Desai ◽  
Johnathan Theodore ◽  
Shubhalakshmi LNU ◽  
Kiran V. Nesvi
Keyword(s):  
Blood Transfusion ◽  
Blood Loss ◽  
Autologous Blood ◽  
Maxillofacial Surgery ◽  
Major Influence ◽  
Oral And Maxillofacial Surgery ◽  
Autologous Blood Transfusion ◽  
Mortality And Morbidity ◽  
Insight Into

Abstract Blood loss has a major influence on mortality and morbidity after surgery. Homologous transfusion has long been in use. With the awareness of associated complications such as risk of transmission of hepatitis and HIV associated with use of homologous transfusion, autologous blood transfusion has gained importance. This paper is an attempt to review the method of autologous blood transfusion, as well as its application in oral and maxillofacial surgery.

scholarly journals The Value of Body Surface Area Used in Postpartum Hemorrhage Define Postpartum Hemorrhage 

2021 ◽  
Author(s):  
Xianyan Lu ◽  
Tao Liu ◽  
Yan Zhou ◽  
Lili Qiu ◽  
Yimin Dai
Keyword(s):  
Blood Transfusion ◽  
Blood Loss ◽  
Surface Area ◽  
Body Surface Area ◽  
Blood Volume ◽  
Body Surface ◽  
Postpartum Hemorrhage ◽  
Total Blood Volume ◽  
Total Blood ◽  
Specificity And Sensitivity

Abstract Background: Blood loss as a percentage of total blood volume for redefining PPH may be more appropriate compared to the 500ml cutoff for every pregnant woman. This study is to investigate the value of body surface area in redefining PPH.Methods: In our prospective clinical observational study, we calculated the total blood volume using body surface area and measured blood loss at delivery using gravimetric and volumetric methods for all pregnant women included in our cohort (n=1715). For the five different body surface area groups, we determined different percentages of blood loss in total blood volume among 1201 participants. Furthermore, we compared the prediction values in blood transfusion based on the quantification of bleeding or proportion of blood loss in total blood volume at different quintiles among 514 severe PPH cases. Results: The median total blood volume and body surface area were 4639ml and 1.73 m2, respectively. The median total blood volume increased with increasing body surface area, and the different proportions of total blood volume increased accordingly. The median blood loss was 380ml and represented 8.28% of total blood volume. The median measured 24h blood loss across quintile 1 to 5 was 363ml, 360ml, 390ml, 380ml, 440ml, respectively. Using the definition with blood loss of 500 ml and 13% percentage of total blood volume, the incidence of PPH was 30% and 19%. However, the changes of the circulatory system secondary to obstetric hemorrhage was not significantly different at each quintile. Additionally, use of blood loss or the percentage of blood loss in total blood volume has high specificity and sensitivity as the indicators to predict blood transfusion.Conclusions: Our results suggest that blood loss exceeds 13% of total blood volume as a definition of postpartum hemorrhage. Blood loss above 30% of total blood volume may be recommended for blood transfusion.

scholarly journals Intraoperative red blood cell salvage and autologous transfusion during open radical retropubic prostatectomy: a cost–benefit analysis

2011 ◽  
Vol 93 (2) ◽  
pp. 157-161 ◽  
Author(s):  
Sarvpreet Ubee ◽  
Manal Kumar ◽  
Nallaswami Athmanathan ◽  
Gurpreet Singh ◽  
Sean Vesey
Keyword(s):  
Blood Transfusion ◽  
Autologous Blood ◽  
Radical Retropubic Prostatectomy ◽  
Autologous Blood Transfusion ◽  
Cell Saver ◽  
Cell Salvage ◽  
Homologous Blood ◽  
Retropubic Prostatectomy ◽  
Group A ◽  
Group B

INTRODUCTION Open radical retropubic prostatectomy (RRP) has an average blood loss of over 1,000ml. This has been reported even from high volume centres of excellence. 1 – 4 We have looked at the clinical and financial benefits of using intraoperative cell salvage (ICS) as a method of reducing the autologous blood transfusion requirements for our RRP patients. MATERIALS AND METHODS Group A comprised 25 consecutive patients who underwent RRP immediately prior to the acquisition of a cell saver machine. Group B consisted of the next 25 consecutive patients undergoing surgery using the Dideco Electa (Sorin Group, Italy) cell saver machine. Blood transfusion costs for both groups were calculated and compared. RESULTS The mean postoperative haemoglobin was similar in both groups (11.1gm/dl in Group A and 11.4gm/dl in Group B). All Group B patients received autologous blood (average 506ml, range: 103–1,023ml). In addition, 5 patients (20%) in Group B received a group total of 16 units (average 0.6 units) of homologous blood. For Group A the total cost of transfusing the 69 units of homologous blood was estimated as £9,315, based on a per blood unit cost of £135. This cost did not include consumables or nursing costs. CONCLUSIONS We found no evidence that autologous transfusions increased the risk of early biochemical relapse or of disease dissemination. ICS reduced our dependence on donated homologous blood.

scholarly journals Fresh Autologous Blood Transfusion and Platelet Counts after Cardiopulmonary Bypass Surgery

1982 ◽  
Vol 10 (4) ◽  
pp. 348-352 ◽  
Author(s):  
V. S. Iyer ◽  
W. J. Russell
Keyword(s):  
Platelet Count ◽  
Blood Transfusion ◽  
Blood Loss ◽  
Autologous Blood ◽  
Early Postoperative Period ◽  
Postoperative Blood Loss ◽  
Control Group ◽  
Substantial Part ◽  
Autologous Blood Transfusion ◽  
Platelet Counts

The effect of fresh autologous blood transfusion on platelet count and blood requirement in the early postoperative period is examined in a control group and in patients receiving early and late autologous replacement. Withdrawal of blood in the autologous groups appeared to enhance platelet numbers as the autologous groups had higher mean platelet counts than the control group immediately after bypass, in spite of having lower mean haematocrit. After bypass all groups showed a progressive rise in platelet count with time. A substantial part of the rise was explained by haemoconcentration resulting from fluid shifts but there was also an increase in the total circulating platelet numbers. There was no difference in postoperative blood loss between the three groups. Autologous blood replacement hastens the postoperative rise in platelet count but does not alter the postoperative blood loss.

scholarly journals Should Autologous Blood Transfusion be Rediscovered?

1980 ◽  
Vol 8 (2) ◽  
pp. 168-171 ◽  
Author(s):  
James P. Isbister ◽  
Richard Davis
Keyword(s):  
Blood Transfusion ◽  
Autologous Blood ◽  
Autologous Blood Transfusion ◽  
Homologous Blood ◽  
Homologous Blood Transfusion ◽  
Efficient Alternative

With a greater appreciation and understanding of reactions to homologous blood transfusion there has been a renewed interest in autologous blood transfusion. The techniques and indications for preoperative banked autologous blood, perioperative haemodilution and recycled salvaged autologous blood transfusion are described. When circumstances permit, autologous blood transfusion is a safe, economical and efficient alternative to homologous blood.

scholarly journals Management of intraperitoneal hemorrhage bleeding as a complication of a gynecologic disease

2014 ◽  
Vol 95 (2) ◽  
pp. 211-216
Author(s):  
O Ya Nazarenko ◽  
S V Timofeyeva
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Blood Transfusion ◽  
Blood Loss ◽  
Autologous Blood ◽  
Blood Substitutes ◽  
Autologous Blood Transfusion ◽  
Blood Products ◽  
Female Patients ◽  
Intraperitoneal Hemorrhage

Aim. To evaluate the effectiveness of intra- and post-surgical resuscitation targeted at blood loss replacement in patients with moderate, severe and profuse intraperitoneal hemorrhage caused by ectopic pregnancy and ovarian apoplexy. Methods. Heart rate variability and cardiac intervals assessment were used as additional criteria for patient monitoring. 97 female patients with intraperitoneal hemorrhage of 500-1500 ml underwent endoscopic surgery. Autologous blood transfusion, as well as packed blood products and blood substitutes were used for blood loss replacement. Heart rate variability assessment and analysis of cardiac intervals indicate that pathogenesis of adaptation and blood loss compensation in female patients with intraperitoneal hemorrhage exceeding 500 ml depends on blood loss volume and methods of blood loss replacement. Results. Parameters of adaptation and blood loss compensatory mechanisms in patients with moderate and severe blood loss, who underwent intrasurgical autologous blood transfusion, were close to normal values at days 7 and 14 after treatment. Patients with severe and profuse intraperitoneal hemorrhage treated with packed blood products had the longest red blood count and heart rate variability recovery period. Conclusion. Heart rate variability assessment allowed effectively estimating the treatment effect in female patients with intraperitoneal hemorrhage as a complication of a gynecologic disease exceeding 500 ml.

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