scholarly journals Neurologic Features Associated With SARS-CoV-2 Infection in Children: A Case Series Report

2021 ◽  
pp. 088307382198916
Author(s):  
Francisca Sandoval ◽  
Katherine Julio ◽  
Gastón Méndez ◽  
Carolina Valderas ◽  
Alejandra C. Echeverría ◽  
...  

Introduction: Although multiple neurologic manifestations associated with SARS-CoV-2 infection have been described in adults, there is little information about those presented in children. Here, we described neurologic manifestations associated with COVID-19 in the pediatric population. Methods: Retrospective case series report. We included patients younger than 18 years, admitted with confirmed SARS-CoV-2 infection and neurologic manifestations at our hospital in Santiago, Chile. Demographics, clinical presentations, laboratory results, radiologic and neurophysiological studies, treatment, and outcome features were described. Cases were described based on whether they presented with predominantly central or peripheral neurologic involvement. Results: Thirteen of 90 (14.4%) patients admitted with confirmed infection presented with new-onset neurologic symptoms and 4 patients showed epilepsy exacerbation. Neurologic manifestations ranged from mild (headache, muscle weakness, anosmia, ageusia), to severe (status epilepticus, Guillain-Barré syndrome, encephalopathy, demyelinating events). Conclusions: We found a wide range of neurologic manifestations in children with confirmed SARS-CoV-2 infection. In general, neurologic symptoms were resolved as the systemic presentation subsided. It is essential to recognize and report the main neurologic manifestations related to this new infectious disease in the pediatric population. More evidence is needed to establish the specific causality of nervous system involvement.

Animals ◽  
2020 ◽  
Vol 10 (7) ◽  
pp. 1210
Author(s):  
Daniel Taasti Melgaard ◽  
Trine Stokbro Korsgaard ◽  
Martin Soendergaard Thoefner ◽  
Morten Roenn Petersen ◽  
Hanne Gervi Pedersen

Unwanted behaviour in mares is a commonly presenting problem to the veterinarian. This behaviour may range from the mare being uncooperative or aggressive when handled on the ground, kicking, bucking or rearing when ridden or being aggressive towards other horses. This purpose of the study was to evaluate whether bilateral ovariectomy in mares with unwanted behaviour improved the mare’s behaviour and/or rideability from the owner’s perspective. The mares were grouped and compared statistically based on their histological classification as having either “normal” or neoplastic ovaries. This study is a retrospective case series report of twenty-eight ovariectomized mares. A semi-quantitative value (1–10) pre- and post-ovariectomy for A) behaviour on ground/in stable and B) rideability was given, based on the owner’s observations. The horses were grouped based on their histopathologic diagnosis as “Normal ovaries” or “Neoplasia”. Following ovariectomy, rideability improved, with a score of ≥5 in 80% (8/10) of mares with normal ovaries and in 57% (8/14) of mares with ovarian neoplasm. A behavioural improvement of ≥5 was observed in 40% (4/10) of mares with normal ovaries, and in 43% (6/14) of mares with ovarian neoplasm. A significant difference was observed between the semi-quantitative value pre- and post-ovariectomy in both groups. No difference was observed in change in behaviour and rideability score between the group with normal ovaries and neoplastic ovaries. Mares with unwanted behaviour not obviously related to the oestrus cycle and to painful conditions may benefit from ovariectomy to alter their behaviour and rideability.


2019 ◽  
Vol 6 (2) ◽  
pp. 308-318 ◽  
Author(s):  
Alessandro Capucci ◽  
Luca Santini ◽  
Stefano Favale ◽  
Domenico Pecora ◽  
Barbara Petracci ◽  
...  

2017 ◽  
Vol Volume 9 ◽  
pp. 111-116 ◽  
Author(s):  
Hani Almoallim ◽  
Sultana Abdulaziz ◽  
Eilaf Fallatah ◽  
Haya Alhazmi ◽  
Nuha Meraiani ◽  
...  

2020 ◽  
Vol 31 (S20) ◽  
pp. 257-257
Author(s):  
Matteo Turra ◽  
Peter Andersson ◽  
Damiano Verrocchi ◽  
Lars Sennerby

Author(s):  
Larissa Marques Santana ◽  
Larissa de Aguiar Martins ◽  
Marcos Rosa-Júnior

Abstract Introduction There are some inflammatory, infectious, and neoplastic diseases affecting the extrinsic orbital musculature (EOM) that present with pain, decreased visual acuity, and proptosis. Imaging is fundamental to the differential diagnoses of these diseases with similar clinical presentations. The present case series report has as main objective to illustrate and discuss the main pathologies that affect the orbit. Material and methods The present series of cases discusses the main pathologies that can affect the extraocular musculature that can be characterized by computed tomography (CT) or magnetic resonance imaging (MRI) using cases from our institution. Results and Discussion The present study compiled several cases of ophthalmopathy from our institution to illustrate and address some of these pathologies, such as orbital lymphoma, Grave disease, metastases, periorbital cellulitis, and idiopathic orbital inflammatory syndrome. The diseases are discussed according to the presentation of clinical cases with emphasis on the main imaging findings of each pathology. Conclusion Computed tomography and MRI can help in the diagnosis and follow-up of the diseases that affect the EOM. We must be conversant with the main characteristics of the pathologies presented in the present case series report, since such findings together with clinical data can confirm the diagnosis of these diseases or at least help to narrow the differential diagnoses.


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