Adipokines and Gut Hormones in End-Stage Renal Disease
2007 ◽
Vol 27
(2_suppl)
◽
pp. 298-302
Keyword(s):
Cachexia is common in end-stage renal disease (ESRD) patients, and it is an important risk factor for poor quality of life and increased mortality and morbidity. Chronic inflammation is an important cause of cachexia in ESRD patients. In the present review, we examine recent evidence suggesting that adipokines or adipocytokines such as leptin, adiponectin, resistin, tumor necrosis factor α, interleukin-6, and interleukin-1β may play important roles in uremic cachexia. We also review the physiology and the potential roles of gut hormones, including ghrelin, peptide YY, and cholecystokinin in ESRD. Understanding the molecular pathophysiology of these novel hormones in ESRD may lead to novel therapeutic strategies.
Keyword(s):
2021 ◽
Vol 18
(7)
◽
pp. 3471
Keyword(s):
Keyword(s):
2007 ◽
Vol 98
(08)
◽
pp. 339-345
◽
Keyword(s):
2010 ◽
Vol 55
(2)
◽
pp. 473-477
◽
2017 ◽
Vol 94
◽
pp. 68-72
◽
Keyword(s):
Keyword(s):