Methadone Maintenance in the Treatment of Narcotics Addiction

1991 ◽  
Vol 4 (6) ◽  
pp. 357-361
Author(s):  
Anthony C. Tommasello

Despite numerous studies documenting its success, methadone maintenance is an often misunderstood and frequently maligned treatment approach for heroin addiction. By taking 40 to 60 mg of methadone orally every day, heroin addicts are able to achieve a degree of stability in their lives allowing them to pursue productive goals while decreasing risky behaviors such as needle sharing and street drug use. Strict admission criteria for methadone maintenance are spelled out in Food and Drug Administration regulations, and those ineligible for methadone maintenance must avail themselves of other forms of treatment. The emergence of Narcotics Anonymous is an encouraging development for heroin addicts who achieve abstinence through a variety of new pharmacotherapeutic options.

PEDIATRICS ◽  
1971 ◽  
Vol 48 (2) ◽  
pp. 173-175
Author(s):  
Saul Blatman

The increasing use of methadone maintenance (substitution) programs1-3 in the treatment of adult heroin addiction has created situations for children which require the attention of pediatricians. Methadone is an analgesic drug. In urban areas, thousands of heroin addicts are now receiving high dosage of methadone, usually 80 to 120 mg daily. This approach to heroin addiction has met with greater success than any other form of treatment. It is expected that increasing numbers of heroin addicts will be treated in the near future by this method throughout the United States and Canada.4 Pediatricians should focus on three aspects of the problem as follows:


2014 ◽  
Vol 42 (03) ◽  
pp. 569-586 ◽  
Author(s):  
Yuan-Yu Chan ◽  
Wan-Yu Lo ◽  
Tsai-Chung Li ◽  
Lih-Jong Shen ◽  
Szu-Nian Yang ◽  
...  

Scant scientific evidence supports the efficacy of acupuncture in the treatment of opiate dependence. The purpose of this study was to examine the effectiveness of acupuncture for heroin addicts on methadone maintenance by measuring the daily consumption of methadone, variations in the 36-item Short Form Health Survey-36 (SF-36) and Pittsburgh Sleep Quality Index (PSQI) scores, and heroin craving. Sixty heroin addicts were randomly assigned to true acupuncture (electroacupuncture at the Hegu [LI4] and Zusanli [ST36] acupoints, as well as acupuncture at the Ear Shenmen) or sham acupuncture (minimal acupuncture at the Hegu and Zusanli acupoints without electrical stimulation and superficial acupuncture at the Ear Shenmen), twice weekly for 4 weeks. From week 2 onwards, the daily dose of methadone was reduced by a significantly greater amount with true acupuncture compared with sham acupuncture. True acupuncture was also associated with a greater improvement in sleep latency at follow-up. All adverse events were mild in severity. Acupuncture appears to be a useful adjunct to methadone maintenance therapy (MMT) in heroin addiction.


1997 ◽  
Vol 27 (2) ◽  
pp. 225-238 ◽  
Author(s):  
James F. Maddux ◽  
David P. Desmond

The authors followed a cohort of 610 opioid users for 1 year after admission to methadone maintenance. At the end of the year, 52% were on methadone and 48% were off methadone. Among subjects on methadone, days of intravenous drug use, crime, and needle-sharing decreased markedly from the month preceding admission to the month preceding the first anniversary of admission. Among subjects off methadone, days of these activities also decreased, but the decreases appeared in large part to be an effect of increased days of incarceration. Among those on methadone, days of productive activity increased markedly. Subjects with more years of intravenous drug use were more likely to be on methadone at the end of the year, and subjects under compulsory supervision were less likely to be on methadone. The findings confirm previous reports of decreased illicit opioid use, decreased crime, and decreased needle risk for infection with the human immunodeficiency virus among opioid users who remain on methadone.


PLoS ONE ◽  
2012 ◽  
Vol 7 (9) ◽  
pp. e45632 ◽  
Author(s):  
Xuyi Wang ◽  
Linxiang Tan ◽  
Yi Li ◽  
Yao Zhang ◽  
Dongyi Zhou ◽  
...  

1995 ◽  
Vol 30 (6) ◽  
pp. 685-698 ◽  
Author(s):  
John R. M. Caplehorn ◽  
Michael W. Ross

2014 ◽  
Vol 13 (2) ◽  
pp. 128-134 ◽  
Author(s):  
Saad Salman ◽  
Muhammad Idrees ◽  
Muhammad Anees ◽  
Jawaria Idrees ◽  
Fariha Idrees ◽  
...  

Objectives: To study the association of attention-deficit hyperactivity disorder (ADHD) with heroin addiction. Study design: A cross-sectional, hospital based study. Place and duration of study: The study was carried out at Lady Reading Hospital and Khyber Teaching Hospital, Peshawar, Pakistan from 4th April 2012 to 13th September 2012. Subjects and Methods: A sample of 137 adult heroin addicts were analyzed that whether they were ADHD and that childhood problem continues to manifest symptoms in adults. For retrospective assessment of childhood ADHD, the Wender Utah Rating Scale (WURS) as well as the Diagnostic and Statistical Manual of Mental Disorders (DSM-IV) symptom checklist for ADHD was used. The Conners’ Adult ADHD Rating Scales (CAARS) was used to assess the persisting symptoms of ADHD in adults. Inclusion criteria: Patient diagnosed with heroin addiction according to ICD-9 and DSM-IV. Exclusion criteria: Patient has co-morbid with any other mental illnesses. Results: The difference between the mean score of WURS and CAARS of ADHD patients were significantly greater than the normal patients. Heroin addicts showed 41.6% (WURS) and 38.6% (DSM-IV diagnostic criteria) that indicated evidence of retrospective ADHD affliction in childhood. 22.6% were IV users. CAARS was presented in 37.9% heroin addicts who exhibited a substantiation of ADHD persistent in adulthood. The difference between the mean score of WURS and CAARS of ADHD patients were significantly greater (P = 0.003), than the normal patients. Conclusions: These results revealed that addiction is associated with co-morbidity with ADHD, expressed in the form of heroin addiction. DOI: http://dx.doi.org/10.3329/bjms.v13i2.18294 Bangladesh Journal of Medical Science Vol.13(2) 2014 p.128-134


1981 ◽  
Vol 12 (4) ◽  
pp. 453-460 ◽  
Author(s):  
Sharon Martinelli Hall ◽  
Peter Loeb ◽  
Michel LeVois ◽  
James Cooper

2004 ◽  
Vol 29 (7) ◽  
pp. 1312-1320 ◽  
Author(s):  
Francesco Leri ◽  
Annie Tremblay ◽  
Robert E Sorge ◽  
Jane Stewart

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