Effects of Preactivated MC540 in the Treatment of Lymphocytic Plasmacytic Stomatitis in Feline Leukemia virus and Feline Immunodeficiency virus Positive Cats

1993 ◽  
Vol 10 (1) ◽  
pp. 9-13 ◽  
Author(s):  
Robert B. Wiggs ◽  
Heidi B. Lobprise ◽  
James L. Matthews ◽  
Kripal S. Gulliya
Keyword(s):  
Feline Immunodeficiency Virus ◽  
Dosage Regimen ◽  
Antitumor Agents ◽  
Leukemia Virus ◽  
Feline Leukemia Virus ◽  
Short Term ◽  
Merocyanine 540 ◽  
Immunodeficiency Virus

Photoactive compounds and drugs are used therapeutically as antibacterial, antiviral and antitumor agents. This report examines the use of a photoactive compound, preactivated merocyanine 540 (pMC540), in the treatment of stomatitis in two cats that are both feline immunodeficiency virus (FIV) positive. One of the cats was also feline leukemia virus (FeLV) positive. Dramatic short term improvement is reported with the dosage regimen and complications.

scholarly journals Prevalence of feline coronavirus, feline leukemia virus, and feline immunodeficiency virus in client-owned cats in Croatia

2021 ◽  
Vol 8 ◽  
pp. 24-38
Author(s):  
Jelena Raukar
Keyword(s):  
Veterinary Medicine ◽  
Feline Immunodeficiency Virus ◽  
Leukemia Virus ◽  
Feline Leukemia Virus ◽  
Antibody Prevalence ◽  
Blood Samples ◽  
Proviral Dna ◽  
Immunodeficiency Virus ◽  
Feline Coronavirus

This study aimed to determine prevalences for anti-FCoV antibody, FeLV antigen, FeLV proviral DNA, and anti-FIV antibody among client-owned cats from the cities of Zagreb and Varaždin in Croatia. Subjects included 106 client-owned cats tested at the Faculty of Veterinary Medicine, Vienna, Austria. Blood samples were tested with IFA for anti-FCoV antibody and IFA FCoV antibody titeres, with ELISA for FeLV p27 antigen, with PCR for FeLV proviral DNA, and with RIM for anti-FIV antibody. Prevalence of FCoV and FeLV was 41.51% and 6.60%, respectively. A coinfection with FeLV/FCoV and FIV/FCoV prevalence was 7.55% and 5.66%. No cats were coinfected with FIV and FeLV. All three viruses were detected, confirming their presence in Croatia. The seroepidemiological findings demonstrate that both feline retroviruses and feline coronavirus are important feline pathogens in Croatia.

Prevalence and Risk Factors for Heartworm Infection in Cats From Northern Florida

2003 ◽  
Vol 39 (6) ◽  
pp. 533-537 ◽  
Author(s):  
Julie K. Levy ◽  
Patti S. Snyder ◽  
Larissa M. Taveres ◽  
Jennifer L. Hooks ◽  
Mike J. Pegelow ◽  
...  
Keyword(s):  
Risk Factors ◽  
Feline Immunodeficiency Virus ◽  
Leukemia Virus ◽  
Clinical Disease ◽  
Feline Leukemia Virus ◽  
Risk Of Infection ◽  
Serological Evidence ◽  
Immunodeficiency Virus ◽  
Heartworm Infection ◽  
Adult Cats

Necropsies were performed on 630 adult cats in northern Florida to determine the prevalence and risk factors for heartworm infection in cats of this region. Heartworms were identified in 4.9% of cats, and serological evidence of heartworm exposure was present in 17% of cats. Not all cats from which heartworms were recovered were seropositive for heartworm antigen or antibody. There was no association between heartworm infection and co-infection with feline leukemia virus (FeLV) or feline immunodeficiency virus (FIV). Male cats were at higher risk of infection with heartworm, FeLV, or FIV than were females. Because even a single heartworm can cause clinical disease or death in cats, the authors conclude that cats in this region should receive heartworm prophylaxis to prevent heartworm infection.

Feline immunodeficiency virus diagnosis after vaccination

2004 ◽  
Vol 5 (2) ◽  
pp. 327-330 ◽  
Author(s):  
Philip R. Andersen ◽  
Phyllis Tyrrell
Keyword(s):  
Western Blot ◽  
Feline Immunodeficiency Virus ◽  
American Association ◽  
Leukemia Virus ◽  
Virus Antigen ◽  
Feline Leukemia Virus ◽  
Antibody Detection ◽  
Predictive Values ◽  
Virus Diagnosis ◽  
Immunodeficiency Virus

AbstractPrior to the widespread use of vaccination for the control of feline immunodeficiency virus (FIV) infection, diagnosis was made by the detection of antibodies against FIV. A number of commercial animal side tests perform quite well for this determination, with positive predictive values between 91 and 100% and negative predictive values between 96 and 100%. Furthermore, results of these tests could be confirmed by western blot analysis of FIV test-positive sera. Currently, a killed whole virus FIV vaccine has been made available to practitioners. Vaccinated cats seroconvert by ELISA and western blot, making presently available diagnostic tests, which rely on antibody detection, useless in cats after vaccination. The advisory panels of the American Association of Feline Practitioners and Academy of Feline Medicine both recommend testing for feline leukemia virus antigen and FIV antibody before vaccination.

scholarly journals Histologic Classification and Immunophenotype of Lymphosarcomas in Cats with Naturally and Experimentally Acquired Feline Immunodeficiency Virus Infections

1996 ◽  
Vol 33 (3) ◽  
pp. 264-272 ◽  
Author(s):  
J. J. Callanan ◽  
B. A. Jones ◽  
J. Irvine ◽  
B. J. Willett ◽  
I. A. P. McCandlish ◽  
...  
Keyword(s):  
B Cell ◽  
Feline Immunodeficiency Virus ◽  
Cell Activation ◽  
Polyclonal Antibodies ◽  
Leukemia Virus ◽  
Feline Leukemia Virus ◽  
B Cell Activation ◽  
Virus Infections ◽  
Histologic Classification ◽  
Immunodeficiency Virus

Lymphosarcoma (malignant lymphoma) is the commonest hematopoietic tumor in the cat. Many cases are associated with feline leukemia virus (FeLV) infection, but epidemiologic and experimental data suggest that feline immunodeficiency virus (FIV) may also have a role in lymphomagenesis. In this paper, we describe the clinical presentation, histologic classification, and immunophenotype of lymphosarcoma in eight domestic cats with natural or experimental FIV infections. The tumors were often of unusual distribution, with the majority of cases conforming to the least common anatomic classification of “miscellaneous.” Histopathologic and immunophenotypic analysis using a panel of anti-cat and cross-reactive anti-human monoclonal and polyclonal antibodies identified seven of these tumors as high-grade B cell lymphomas of the centroblastic or immunoblastic subtypes. The remaining case was a T-cell tumor associated with a concurrent FeLV infection. Our findings, together with the results of an analysis of FIV proviral DNA in these tumors, indicate that the B-cell lymphosarcomas were comparable to those observed in human and simian immunodeficiency virus infections and that the role of FIV in lymphomagenesis is indirect and related to the potential for malignant transformation during polyclonal B cell activation.

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