Effects of subacute exposure to 1,2-dichloroethane on mouse behavior and the related mechanisms

2012 ◽  
Vol 32 (9) ◽  
pp. 983-991 ◽  
Author(s):  
G. Wang ◽  
Y. Qi ◽  
L. Gao ◽  
G. Li ◽  
X. Lv ◽  
...  
Keyword(s):  
Mouse Behavior ◽  
Subacute Exposure

Development of a Rat Model for Subacute Exposure to the Toxic Organophosphate VX

1996 ◽  
Vol 15 ◽  
pp. 69-77 ◽  
Author(s):  
D. E. Lenz ◽  
D. M. Maxwell ◽  
L. W. Austin
Keyword(s):  
Rat Model ◽  
Subacute Exposure

Enantiomers of 4‐aminopentanoic acid act as false GABAergic neurotransmitters and impact mouse behavior

2021 ◽  
Author(s):  
Adam M. Wawro ◽  
Chandresh R. Gajera ◽  
Steven A. Baker ◽  
Robert K. Leśniak ◽  
Kathleen S. Montine ◽  
...  
Keyword(s):  
Mouse Behavior

Effect of Subacute Exposure to Lead and Estrogen on Immature Pre-Weaning Rat Leukocytes

1997 ◽  
Vol 58 (2) ◽  
pp. 190-197 ◽  
Author(s):  
R. Villagra ◽  
N. N. Tchernitchin ◽  
A. N. Tchernitchin
Keyword(s):  
Subacute Exposure

Alterations in Electrocardiographic Parameters after Subacute Exposure of Fluoride and Ameliorative Action of Aluminium Sulphate in Goats

2009 ◽  
Vol 134 (2) ◽  
pp. 188-194 ◽  
Author(s):  
Vinay Kant ◽  
Anil Kumar Srivastava ◽  
Pawan Kumar Verma ◽  
Rajinder Raina ◽  
Nrip Kishore Pankaj
Keyword(s):  
Aluminium Sulphate ◽  
Electrocardiographic Parameters ◽  
Subacute Exposure

scholarly journals Repeated Cortico-Striatal Stimulation Generates Persistent OCD-Like Behavior

Science ◽  
2013 ◽  
Vol 340 (6137) ◽  
pp. 1234-1239 ◽  
Author(s):  
Susanne E. Ahmari ◽  
Timothy Spellman ◽  
Neria L. Douglass ◽  
Mazen A. Kheirbek ◽  
H. Blair Simpson ◽  
...  
Keyword(s):  
Obsessive Compulsive Disorder ◽  
Orbitofrontal Cortex ◽  
Progressive Increase ◽  
Repetitive Behaviors ◽  
Mouse Behavior ◽  
First Line ◽  
Obsessive Compulsive ◽  
Compulsive Disorder ◽  
Chronic Fluoxetine

Although cortico-striato-thalamo-cortical (CSTC) circuit dysregulation is correlated with obsessive compulsive disorder (OCD), causation cannot be tested in humans. We used optogenetics in mice to simulate CSTC hyperactivation observed in OCD patients. Whereas acute orbitofrontal cortex (OFC)–ventromedial striatum (VMS) stimulation did not produce repetitive behaviors, repeated hyperactivation over multiple days generated a progressive increase in grooming, a mouse behavior related to OCD. Increased grooming persisted for 2 weeks after stimulation cessation. The grooming increase was temporally coupled with a progressive increase in light-evoked firing of postsynaptic VMS cells. Both increased grooming and evoked firing were reversed by chronic fluoxetine, a first-line OCD treatment. Brief but repeated episodes of abnormal circuit activity may thus set the stage for the development of persistent psychopathology.

Quantitative Genetics and Mouse Behavior

2001 ◽  
Vol 24 (1) ◽  
pp. 845-867 ◽  
Author(s):  
Jeanne M Wehner ◽  
Richard A Radcliffe ◽  
Barbara J Bowers
Keyword(s):  
Quantitative Genetics ◽  
Mouse Behavior
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