Serum Bovine Immunoglobulin for Chemotherapy-Induced Gastrointestinal Mucositis

2017 ◽  
Vol 35 (5) ◽  
pp. 814-817 ◽  
Author(s):  
Sowminya Arikapudi ◽  
Saima Rashid ◽  
Laith Adel Al Almomani ◽  
Jennifer Treece ◽  
Steven J. Baumrucker
Keyword(s):  
Gastrointestinal Mucositis ◽  
Bovine Immunoglobulin

Oral serum bovine immunoglobulin improves IBS-D symptoms analyzed from patient medical charts.

2017 ◽  
Vol 01 (01) ◽  
Author(s):  
Larry Good ◽  
Audrey Shaw ◽  
David Wei ◽  
Rene E. Vasquez ◽  
Raymond Panas ◽  
...  
Keyword(s):  
Bovine Immunoglobulin

scholarly journals Antigenic Crossreactivity and Lipopolysaccharide Neutralization Properties of Bovine Immunoglobulin G

1995 ◽  
Vol 78 (12) ◽  
pp. 2745-2752 ◽  
Author(s):  
G.M. Tomita ◽  
D.A. Todhunter ◽  
J.S. Hogan ◽  
K.L. Smith
Keyword(s):  
Immunoglobulin G ◽  
Bovine Immunoglobulin

scholarly journals Velafermin improves gastrointestinal mucositis following irinotecan treatment in tumor-bearing DA rats

2007 ◽  
Vol 6 (4) ◽  
pp. 541-547 ◽  
Author(s):  
Rachel J Gibson ◽  
Andrea M Stringer ◽  
Joanne M Bowen ◽  
Richard M Logan ◽  
Ann S-J Yeoh ◽  
...  
Keyword(s):  
Tumor Bearing ◽  
Gastrointestinal Mucositis

The impact of oral cryotherapy and oral and gastrointestinal mucositis after autologous stem cell transplantation

2014 ◽  
Vol 18 (2) ◽  
pp. 228-229 ◽  
Author(s):  
Samuel Vokurka ◽  
Ivana Chvojkova ◽  
Tomas Svoboda ◽  
Renata Brandejsova ◽  
Alexandra Jungova ◽  
...  
Keyword(s):  
Stem Cell ◽  
Stem Cell Transplantation ◽  
Cell Transplantation ◽  
Autologous Stem Cell Transplantation ◽  
Oral Cryotherapy ◽  
Gastrointestinal Mucositis ◽  
The Impact

scholarly journals Clinical and Pathologic Remission of Pediatric Ulcerative Colitis with Serum-Derived Bovine Immunoglobulin Added to the Standard Treatment Regimen

2017 ◽  
Vol 11 (2) ◽  
pp. 335-343 ◽  
Author(s):  
Rachelle A. Soriano ◽  
Asuncion G. Ramos-Soriano
Keyword(s):  
Ulcerative Colitis ◽  
Treatment Regimen ◽  
Pediatric Patients ◽  
Opportunistic Infections ◽  
Activity Index ◽  
Mucosal Healing ◽  
Chronic Inflammatory Bowel Disease ◽  
Medical Food ◽  
Markers Of Inflammation ◽  
Bovine Immunoglobulin

Ulcerative colitis (UC) is a chronic inflammatory bowel disease that is particularly troublesome for pediatric patients, as current therapeutic options consist of biologic agents and steroids which alter the immune response and have the harmful side effect of leaving the patient more susceptible to opportunistic infections and eventual surgery. Another option for therapy exists in the form of serum-derived bovine immunoglobulin/protein isolate (SBI), the key ingredient in a medical food, EnteraGam®. The FDA has reviewed the safety of SBI and issued a no challenge letter to the generally recognized as safe (GRAS) findings for this medical food. The product also has no known food or drug interactions, no significant adverse effects, and no contraindications, save for beef allergy. SBI has been shown to induce clinical remission in adult populations and to decrease markers of inflammation in pediatric patients. Here, we present a detailed case of pediatric UC, including documentation of mucosal healing and decrease in pediatric UC activity index in a difficult to treat pediatric patient, after the addition of SBI to this patient’s treatment regimen.

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