This chapter adopts an interpretive, case based research strategy to discuss the centrality of meaning in implementing an Internet-based self-service technology. Actor-Network theory (ANT) is used to describe the complex evolution of a Web-based service at a healthcare insurance firm. Using processes of inscribing, translating and framing, this chapter explores the emergence of the technology from 1999 – 2005 using three technological frames, ‘channel of choice’, ‘dazzle the customer’, and ‘complementary channel’ as episodes of translation. ANT demonstrates that the Internet-based self-service technology at this particular healthcare context emerged out of many unplanned negotiations and mediations with both human and non human actors. Finally, this chapter argues that ANT’s socio-technical lens provides a richer understanding of the meaning of Internet-based self-service technology within a multi-channel context.