scholarly journals SITUATION OF DRUGS FOR TREATMENT INTESTINAL INFECTION

2021 ◽  
Vol 62 (4) ◽  
Author(s):  
Lam Hoang Khanh ◽  
Nguyen Huu Phuc ◽  
Bui Tung Hiep ◽  
Bui Dang Minh Tri
Keyword(s):  
Medical Records ◽  
Pediatric Patients ◽  
Antibiotic Regimen ◽  
Intestinal Infection ◽  
Beta Lactam ◽  
Cross Sectional ◽  
Children's Hospital ◽  
Frequency Of Use ◽  
Children’S Hospital ◽  
Can Tho City

Objective: To survey the use of drugs to treat intestinal infection at Can Tho Children’s Hospital. Objects and methods: Cross-sectional retrospective descriptive study on 400 medical records of pediatric patients diagnosed with intestinal infection in Can Tho City Children’s Hospital in 2019. Result: There were 353 pediatric patients using rehydration and electrolytes measeurement, ORS with the highest frequency was 38.66%. The antibiotic with the highest frequency of use was the beta-lactam 3rd group. In which, Cefotaxim had the most use frequency. Single regimen of cefotaxim used the most with a frequency of 70.06%. Meanwhile, the antibiotic regimen cefotaxime combined with tobramycin was the highest in the combined regimen with 57.14%. Up to 70 cases changed the regimen due to ineffective results and 22 cases changed the regimen due to its effectiveness, reducing the amount of antibiotics. The first regimen with the highest frequency of change was the cefotaxim regimen with 33 cases. The 2nd regimens changed with the highest frequency were cefotaxim regimen and regimen of cefotaxim combined with tobramycin with 5 cases. The third change of regimen was mostly from combination antibiotic regimen to single regimen. Conclusion: Rehydration and electrolyte measures were mainly ORS. Antibiotics used mainly in the beta-lactam 3rd group, Cefotaxim had the highest frequency of use. Cefotaxim was used the most frequency in a single regimen. The antibiotic combined regimen between cefotaxime and tobramycin was the highest use in all combined regimens. Changing treatment regimen was mainly due to the ineffective effect.

scholarly journals THE REASONABLENESS OF USING DRUGS TO TREAT PNEUMONIA

2021 ◽  
Vol 62 (4) ◽  
Author(s):  
Nguyen Viet Dang ◽  
Tri Kim Ngoc ◽  
Bui Tung Hiep ◽  
Bui Dang Minh Tri
Keyword(s):  
Treatment Regimen ◽  
Medical Records ◽  
Initial Treatment ◽  
Descriptive Study ◽  
Antibiotic Regimen ◽  
Children's Hospital ◽  
Children’S Hospital ◽  
Antibiotic Dose ◽  
Very High ◽  
Antibiotic Delivery

Objective: To investigate the reasonableness of using drugs to treat pneumonia at Can Tho Children’s Hospital. Subjects and methods: a retrospective-descriptive study on 384 inpatient medical records at Can Tho Children’s Hospital from January 2019 to December 2019 was diagnosed pneumonia. Results: The percentage of the initial treatment regimen that was not reasonable with the recommended antibiotic regimen was relatively high at 84.11%. The proportion of antibiotics with inappropriate dose was only 1.71% of the total number of surveyed cases. The appropriate rate of antibiotic dose was 98.29%. The proportion of adjuvants with high appropriate doses such as Salbutamol, Hydrocortison and Prednisolon accounted for 100%. The rate of taking antibiotics in accordance with recommendations accounted for 94.67%. The rate of adjuvanvt drug delivery was very high, there were only a few cases that did not comply with recommendations such as Ibuprofen with 14 cases, accounting for 37.84%, Acetylcysteine ​​and Hydrocortison accounted for 14.58% with 7 cases, and Prednisolon and Budesonid accounted for the very low percentage. Conclusion: The proportion of the initial treatment regimen that was not compatible with the antibiotic regimen was relatively high. The appropriate rate of antibiotic dose was high. The proportion of adjuvants with suitable doses was high such as Salbutamol, Hydrocortison and Prednisolon. The antibiotic delivery rate was consistent with recommendations. The rate of adjuvant delivery was very high.

THE CHARACTERISTICS OF CLINICLA AND PARACLINICAL IN ACUTE DIARRHEA CHILDREN PATIENT AT VIETNAM NATIONAL CHILDREN'S HOSPITAL

2020 ◽  
Vol 4 (3) ◽  
Author(s):  
Hoàng Ngọc Anh
Keyword(s):  
Escherichia Coli ◽  
Acute Diarrhea ◽  
Pediatric Patients ◽  
Cross Sectional ◽  
Fishy Odor ◽  
Children's Hospital ◽  
Children’S Hospital ◽  
Mild Fever

Objectives: To descriptive of clinical and subclinical characteristics of pediatric patients with acute diarrhea at Vietnam national children's hospital in 2019. Subjects: Children diagnosed with acute diarrhea at Vietnam national children's hospital from January 2019 to December 2019. Method: Cross-sectional description. Results and conclussion: 63.7% of children had vomiting, of which 59.2% vomited 5-10 times / day. 55.7% had a mild fever. 20.7% had dehydration. 76.7% of yellow feces and 77.3% of feces had no fishy odor. The majority of children had leukocytes, increased hematocrit. 55.1% of children had Escherichia coli in their stool.  

Efficacy and duration of propranolol therapy for pediatric parotid hemangiomas

2018 ◽  
pp. 1-5
Keyword(s):  
Electronic Medical Records ◽  
Retrospective Review ◽  
Medical Records ◽  
Pediatric Patients ◽  
Vascular Anomalies ◽  
Children's Hospital ◽  
Children’S Hospital ◽  
Anatomic Locations ◽  
Propranolol Therapy

Objective: To assess the efficacy and duration of propranolol therapy in pediatric patients with parotid hemangiomas, and compare the results with the efficacy and duration of propranolol therapy in patients with infantile hemangiomas in other anatomic locations. Methods: In this retrospective review, we analyzed the electronic medical records of 21 patients with parotid hemangiomas seen at the Children’s Hospital of Orange County’s Vascular Anomalies Clinic between 2009 and 2015. We compared the duration of propranolol therapy and rate of re-growth after completion of therapy with established data for these parameters in the literature for patients with other infantile hemangiomas. Results: In our cohort, 13 of the 21 patients had completed therapy, with a mean duration of 26 months of propranolol therapy. Eighteen patients (85.7%) were treated with the goal dose of propranolol (2 mg/kg/day). Three patients required a higher dose in order to achieve significant improvement in the size of the hemangioma. All patients had some response to propranolol. Eight of the 13 patients (61.5%) who completed propranolol therapy saw regrowth once initial propranolol therapy was either weaned or stopped. Conclusion: Pediatric patients with parotid hemangiomas require longer duration of propranolol therapy than patients with other infantile hemangiomas, and a greater percentage may have regrowth after completion of therapy.

scholarly journals SỰ PHÙ HỢP TRONG SỬ DỤNG THUỐC ĐIỀU TRỊ BỆNH TAY CHÂN MIỆNG

2021 ◽  
Vol 62 (2) ◽  
Author(s):  
Bùi Đặng Lan Hương ◽  
Bùi Đặng Phương Chi ◽  
Trần Thị Kiều Trinh
Keyword(s):  
Immunoglobulin G ◽  
Foot And Mouth Disease ◽  
Utilization Rate ◽  
Disease Treatment ◽  
Cross Sectional ◽  
Children's Hospital ◽  
Oral Medications ◽  
Significant Difference ◽  
Children’S Hospital ◽  
Can Tho City

Objective: To evaluate the appropriateness in using drugs of hand, foot and mouth disease treatment at the Children’s Hospital of Can Tho city in 2019. Subjects and methods: Retrospective cross-sectional descriptive study on 400 medical records of inpatients at Can Tho Children’s Hospital during the period from January 2019 to December 2019. Results: There was a statistically significant difference between the group of patients using the dose appropriate to the prescribed dose (P = 0.000 <0.005). Drugs with the most suitable delivery rhythm were Paracetamol, Midazolam, Diazepam, Adrenalin, Dobutamim, Immunoglobulin G, Cefuroxim with 100% as recommended. The lowest rate of used drugs compared to the recommendations was Cefotaxim (89.9%) and Ceftriaxon (83.3%). The most used oral medications: Paracetamol, Ibuprofen, Phenobarbital, Chlorpheniramine, Diazepam, Adrenalin, Dobutamim, Immunoglobulin G were suitable to the 100% recommendation. The lowest appropriate rate compared with the recommendation was Cefuroxime, which accounted for 6.7%, using the injection route in accordance with the recommendation. The more common pair of interactions was Paracetamol and Phenobabital concomitantly accounted for 90.6% of the total 149 of the recorded interactions and a lower proportion was the pair of Midazolam with Phenobabital, accounting for 9.4%. Conclusion: Most drugs with highly suitable indications for use, of which the highest were Paracetamol, Diazepam, Adrenalin, Dobutamim, Immunoglobulin G. Antibiotics had the lowest appropriate utilization rate.

Utilization of Pain Rating Scales in Peadiatric Care Among Health Professionals in A Tertiary Children’s Hospital in Kenya

2021 ◽  
Vol 2 (2) ◽  
pp. 47-64
Author(s):  
Godfrey Mbaabu Limungi ◽  
Dr Drusilla Makworo ◽  
Dr Sherry Oluchina ◽  
Dr Patrick M. Mburugu
Keyword(s):  
Health Professionals ◽  
Medical Records ◽  
Qualitative Data ◽  
Rating Scales ◽  
Unique Contribution ◽  
Pain Rating ◽  
Cross Sectional ◽  
Children's Hospital ◽  
Qualitative Approaches ◽  
Children’S Hospital

Purpose: The study assessed utilization of pain rating scales at a children’s hospital as a basis for making recommendation for their adoption by the ministry of health, Kenya. Methodology: This was a descriptive cross-sectional study utilizing both quantitative and qualitative approaches, conducted in a tertiary children’s hospital in Nairobi-Kenya. Data was collected using semi- structured self-administered questionnaire, key informant interview guide (KII) and observation check list from a sample size of 160 Health Professionals and 71 patients’ medical records sampled from a study population of 280 Health professionals and 88 patients’ medical records. Quantitative data was analyzed using descriptive statistics where by data was summarized using frequency tables and presented using pie chart, and bar graphs. A content analysis was performed on qualitative data based on stages of qualitative data analysis.Results: The hospital was found to have adopted four pain rating scales which included Neonatal guide score, FLACC, Wong Baker faces scale, and Numerical pain scale. Utilization of these tools among Health Professionals was found to be excellent, with nurses being the main health professionals who utilized them at 99%. Unique contribution to theory, practice and policy:  This study aims at improving pain management in child health care in Kenya, where many paediatric units do not assess and measure pain in paediatric patients. Though nurses were the main Health Professionals who utilized pain rating scales in the hospital, inclusion of pain guidelines in all patient’s medical records would promote their utilization among other Health Professionals

scholarly journals A Retrospective Review of Hospital-Acquired Venous Thromboembolism at a Large Pediatric Tertiary Care Center

Blood ◽  
2019 ◽  
Vol 134 (Supplement_1) ◽  
pp. 3471-3471
Author(s):  
Marissa A. Just ◽  
Joanna Robles ◽  
Karan R. Kumar ◽  
Andrew Yazman ◽  
Jennifer A. Rothman ◽  
...  
Keyword(s):  
Retrospective Review ◽  
Research Funding ◽  
Pediatric Patients ◽  
Central Venous ◽  
Vte Prophylaxis ◽  
Children's Hospital ◽  
Congenital Cardiac Disease ◽  
Children’S Hospital ◽  
Icd 10 ◽  
Hospital Acquired

Introduction: The incidence of venous thromboembolism (VTE) in hospitalized pediatric patients is increasing secondary to the growing medical complexity of pediatric patients and the increasing use of central venous catheters. Pediatric patients diagnosed with VTE have up to 2% mortality associated directly with their thromboses. While incidence, risk factor identification and preventive strategies are well established in hospitalized adults, this information is limited in the pediatric population. There are currently no standardized VTE risk screening tools or thromboprophylaxis guidelines for children at Duke Children's Hospital. The incidence of hospital acquired VTE (HA-VTE), as well as their associated risk factors were investigated in a retrospective review. Methods: Medical records of pediatric patients hospitalized at Duke Children's Hospital during June 2018 through November 2018 were reviewed. The EPIC SlicerDicer tool was used to identify patients with ICD-10 diagnoses codes related to thrombosis or treated with anticoagulants. Included patients were diagnosed with HA-VTE during their hospitalization or within 14 days of discharge. Data collected included demographics, thrombosis characteristics, family history, mobility, and acute or chronic co-morbid conditions. The characteristics of the study population were described by median (with 25th and 75th percentiles) for continuous variables and frequencies (with percentages) for binary or categorical variables. Results: Out of 4,176 total pediatric admissions to all units of Duke Children's Hospital (ages 0-18.99 years) during the inclusion timeframe, 33 VTE events were identified. The incidence of VTE events per 1000 patient days was 0.98. The complete patient and VTE event characteristics are listed in Tables 1 and 2. The median age of patients with VTE events was 0.4 years. Of the identified cohort, 73% had an associated central venous line (CVL). Neonates with congenital cardiac disease comprised the majority of the cohort. Other common patient characteristics observed in this cohort included impaired mobility, recent major surgery, and recent mechanical ventilation. Of the 33 VTE diagnoses, 70% received therapeutic anticoagulation with enoxaparin or unfractionated heparin. Only 2 patients (8%) received prophylactic anticoagulation prior to their diagnosis of VTE. Conclusions: The retrospective review of HA-VTE events at Duke Children's Hospital identified that the majority of the events occurred in neonates with congenital cardiac disease and the presence of CVLs. It was also noted that there was no standardization among the use of anticoagulation agents that were initiated for treatment of VTE. Furthermore, few patients received VTE prophylaxis during the hospitalization. A limitation of this review was that it was retrospective and the documentation of family history of thrombosis was inconsistent. It is also possible that several VTE events were missed due to inadequate ICD-10 coding. Based on the results of this review, there is a need to implement a risk stratification tool and develop standardized recommendations of VTE prophylaxis and treatments for pediatric patients admitted to Duke Children's Hospital. There is an additional quality improvement phase of this project and the goal is to implement a risk calculator that is based on information learned from the retrospective review. Ultimately, this risk calculator will help to decrease the incidence of VTE events at Duke Children's Hospital. Disclosures Rothman: Agios: Honoraria, Research Funding; Pfizer: Consultancy, Honoraria, Research Funding; Novartis: Honoraria, Research Funding.

scholarly journals Improving Pediatric Adverse Drug Event Reporting through Clinical Pharmacy Services

2011 ◽  
Vol 16 (4) ◽  
pp. 285-290
Author(s):  
David M. Crowther ◽  
Marcia L. Buck ◽  
Michelle W. McCarthy ◽  
Virginia W. Barton
Keyword(s):  
Causative Agent ◽  
Adverse Drug Event ◽  
Pediatric Patients ◽  
Drug Event ◽  
University Of Virginia ◽  
Children's Hospital ◽  
Therapeutic Class ◽  
Children’S Hospital ◽  
The University

OBJECTIVES The purpose of this study was to summarize adverse drug event (ADE) reporting and to characterize the type of healthcare practitioners involved in reporting over a 10-year period at a 120-bed university-affiliated children's hospital. METHODS The University of Virginia Children's Hospital ADE database was analyzed for records involving pediatric patients. Data from patients &lt;18 years of age who were admitted to the University of Virginia Children's Hospital between January 1, 2000, and December 31, 2009, were analyzed. Data collected included drug name and therapeutic class of the suspected causative agent, description of the event, severity, causality, outcome, and the type of healthcare practitioner reporting the event. RESULTS A total of 863 ADEs were reported over the 10-year period. The 5 most common types reported were extravasation injury (10%), rash (8%), hypotension (5%), pruritus (5%), and renal failure (3%). A total of 196 (21%) cases were categorized as mild, 436 (47%) cases as moderate, and 296 (32%) cases as severe. Further characterization of extravasations was performed to identify trends relating to potential causes. In 45 (57%) reports, parenteral nutrition was identified as the causative agent. Full recovery was documented in 21 (47%) extravasations. Of the total events reported, 83% were reported by pharmacists, 16% by nurses, and &lt;1% by other healthcare practitioners. CONCLUSIONS Results of this study are consistent with those of previous studies involving ADE reporting in children's hospitals. This consistency is due in part to system design and use of unit-based pharmacists as the primary reporters.

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