scholarly journals Sero-Prevalence of HBV and its Associated Factors Among Healthcare Providers in Public Health Facilities in Eastern Ethiopia

2022 ◽  
Vol 15 ◽  
pp. 117863372110626
Author(s):  
Degu Abate ◽  
Abebe Tolera ◽  
Behailu Hawulte ◽  
Tewodros Tesfa ◽  
Ayele Geleto

Background: Healthcare providers are in high occupational risk of Hepatitis B virus infection than that of the general population because of the high risk of occupational exposure to patients’ body fluids and accidental sharp injuries. There are no large facility-based studies conducted on the prevalence of HBV infection and its associated factors among health care providers in eastern Ethiopia. Objective: This study aimed at investigating the seroprevalence of Hepatitis B Virus and its associated factors among the healthcare providers in public health facilities in eastern Ethiopia. Methods: A facility-based cross-sectional study was conducted among 438 randomly selected healthcare providers in eastern Ethiopia from March to June 2018. Pretested structured questionnaire was used to collect data on socio-demographic characteristics and other risk factors. In addition, a 2.5 ml blood was collected and the serum was analyzed for Hepatitis B surface antigen using the Instant Hepatitis B surface antigen kit. Data were entered using Epidata version 3.1 and analyzed using SPSS statistical packages version 22. Descriptive summary measures were used. Bivariate and multivariable logistic regression was conducted at 95% CI. An association at P-value <.05 was considered statistically significant. Results: A total of 438 (92.02% response rate) health care providers have participated in this study. The prevalence of hepatitis B virus infection was 9.6%. There were no significant differences in the HBV infection rates among healthcare providers with respect to socio-demographic characteristics ( P-value >.05). After adjusting for some variables, the following variables remained statistically significantly associated with HBsAg positive result in the multivariable analysis: exposure to body fluids (AOR = 3.0; 95% CI [1.25, 7.05]), history of needle stick injury (AOR = 4.70; 95% CI [2.10, 10.55]), history of operation/surgery (AOR = 4.88, 95% CI [1.43, 16.62]), history of multiple sexual partner (AOR = 7.48; 95% CI [2.08, 26.96]), and being unvaccinated (AOR = 6.09; 95% CI [2.75, 13.51]). Conclusion: This study showed a high prevalence of HBV infection among health care providers in eastern Ethiopia. This is significant because health professionals may be at increased risk of chronic complications and may also be source of infection for their clients and general population during their healthcare practice. Management commitment that should focus on occupational safety and health promotions is necessary.

2017 ◽  
Vol 40 (2) ◽  
pp. 103-114
Author(s):  
Md Rukunuzzaman ◽  
ASM Bazlul Karim ◽  
Mohammed Nurullah ◽  
Md Wahiduzzaman Mazumder ◽  
Md Atiar Rahman ◽  
...  

This guideline has been written to make familiar childhood hepatitis B virus (HBV) infection management for the pediatrician of Bangladesh. To develop this guideline, local & international data reviewing and several international practice guideline on the management of HBV infection were searched webs. This guideline has been developed to assist pediatric gastroenterologists, pediatricians and other health care providers for the management of HBV in Bangladesh. Objective of these guidelines is to give updated information in the management of HBV infection.Bangladesh J Child Health 2016; VOL 40 (2) :103-114


2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Degu Abate Mengiste ◽  
Abebe Tolera Dirbsa ◽  
Behailu Hawulte Ayele ◽  
Tewodros Tesfa Hailegiyorgis

Abstract Background The risk of hepatitis B virus infection among medical waste handlers who undergo collection, transportation, and disposal of medical wastes in the health institutions is higher due to frequent exposure to contaminated blood and other body fluids. There is limited evidence on the seroprevalence of hepatitis B among medical waste handlers in eastern Ethiopia. The study was aimed at studying the seroprevalence of Hepatitis B Virus and associated risk factors among medical waste collectors at health facilities of eastern Ethiopia. Methods A facility-based cross-sectional study was conducted among randomly selected medical waste collectors from public health facilities in eastern Ethiopia from March to June 2018. A pre-tested and well-structured questionnaire was used to collect data on socio-demographic characteristics and hepatitis B infection risk factors. A2.5ml venous blood was also collected, centrifuged and the serum was analyzed for hepatitis B surface antigen using the instant hepatitis B surface antigen kit. Descriptive summary measures were done. Chi-square and Fisher exact tests were used to assess the risk of association. Multivariate logistic regression was conducted with 95% CI and all value at P-value < 0.05 was declared statistically significant. Results From a total of 260 (97.38%) medical waste collectors participated, HBV was detected in 53 (20.4%) of the participants [95%CI; 15.8, 25.6]. No significant differences were observed in the detection rates of HBV with respect to socio-demographic characteristics. In both bivariate and multivariable logistic regression analysis, being unvaccinated (AOR = 6.35; 95%CI = [2.53–15.96], P = 0.001), history of blood transfusion (receiving) (AOR; 3.54; 95%CI; [1.02–12.24], P = 0.046), history of tattooing (AOR = 2.86; 95%CI = [1.12–7.27], p = 0.03), and history of multiple sexual partner (AOR = 10.28; 95%CI = [4.16–25.38], P = 0.001) remained statistically significantly associated with HBsAg positivity. Conclusion This cross-sectional study identified that HBV infection is high among medical waste collectors in eastern Ethiopia. Immunization and on job health promotion and disease prevention measures should be considered in order to control the risk of HBV infection among medical waste collectors in eastern Ethiopia.


Author(s):  
Naif Tawfiq Alnwany

Aim: This study was conducted to determine the prevalence of hepatitis B virus (HBV) and associated factors. Method: A cross-sectional study was conducted on randomly (simple random sample according to previous seroprevalence HBV in population) selected 500 blood donors from who came to the blood bank service in 48 Hospital in Sana'a between October 2016 to Aug 2016 and were interviewed face to face, then data was collected by using questionnaire and blood samples collected after that using enzyme-linked immunosorbent assay technique. the questionnaire consisted of three sections (A) demographics, (B) associated factors and (C) blood sample results. Results and conclusion: The prevalence of hepatitis B virus infected was 2.6%. Only three factors in simple and multiple logistic regression were statistically significant with prevalence of HBsAG. Multiple logistic regression analysis showed that blood donors who had history of: dental treatment, cupping and malaria infection were more likely to infect with hepatitis B virus infected compared to those without history of: dental treatment, cupping and malaria infection 7.8%, 7.3 % and 7.5 % respectively. The rest of factors failed to achieve any statistical significant with prevalence of HBsAG. Hepatitis b is hyper endemic in Yemen, this need application of infection control policies in dental clinics, cupping centers, inject Hepatitis B virus vaccine and control of malaria in endemic areas.


PLoS ONE ◽  
2020 ◽  
Vol 15 (10) ◽  
pp. e0241226
Author(s):  
Nefsu Awoke ◽  
Henok Mulgeta ◽  
Tsegaye Lolaso ◽  
Tiwabwork Tekalign ◽  
Serawit Samuel ◽  
...  

2019 ◽  
Author(s):  
Haile Workye Agazhu ◽  
Melese Niguse Robele ◽  
Ijigu Tadesse Ayele ◽  
Amin A/Karim Mohammed

Abstract Background; Hepatitis B virus (HBV) is the world’s most common and highly contagious liver infection. Its transmission methods are: mother to child, via open wounds, sexual contact, blood transfusion and other blood contact related activities. Prevalence of HBV among pregnant women in Africa ranges from 3.67 - 16.5% and in Ethiopia 2.4 to 8.4%. Hepatitis B infection leads to high morbidity and mortality for mother as well as for their infants due to the vertical transmission. Hence assessing the prevalence and associated factors of Hepatitis B Virus infection is a priority. Methodology : An institution based cross sectional study was conducted with a total of 194 of pregnant women attending antenatal care at Agena health center from May 1-30/2019. Frequency analysis and Logistic regression test was used to determine the associated factors associated with Hepatitis B virus by using SPSS version 25. Results: The prevalence of HBV in Agena health center among pregnant women were 4.1% and it was associated with marital status, history of hospital admission and history of abortion. Conclusion : The prevalence of HBV in Agena health center among pregnant women was intermediate. Since routine screening and immunization of all pregnant women is mandatory. Key words : Hepatitis B infection, pregnant women, Agena health center


2005 ◽  
Vol 18 (4) ◽  
pp. 295-309
Author(s):  
Naomi S. Boston ◽  
Judianne C. Slish

Co-infection with hepatitis C virus (HCV) and/or hepatitis B virus (HBV) is becoming a rampant disparity in HIV-infected patients. The advent of antiretroviral therapy has led to agents that are effective for suppression of both HIV and HBV; however, this can not be extrapolated to patients who are coinfected with HCV. Treatment of HCV disease is often strenuous and can lead to untoward adverse effects. Co-infection with HIV often leads to higher rates of cirrhosis and liver failure in patients with HBV or HCV, compromising antiretroviral treatment in this patient population due to the hepatotoxicity of these agents. The purpose of this review is to familiarize health care providers to the management of HIV infection in patients who are also co-infected with HBV or HCV.


2020 ◽  
Author(s):  
Mhiret Belay Tadiwos ◽  
Girum Gebremeskel Kanno ◽  
Abereham Shiferaw Areba ◽  
Mekonnen Birhanie Aregu

Abstract Background: Hepatitis B virus infection is a major public health problem worldwide which is a major cause of morbidity and mortality. This study aimed to assess the prevalence of hepatitis B virus infection and associated factors among pregnant mothers in Gedio Zone, southern Ethiopia.Methods: Institutional based cross-sectional study was conducted in governmental and private health facilities in Gedeo zone from January to April 2019. The study participants were selected using stratified random sampling techniques. Eugene strip test was used to determine hepatitis B virus infection among pregnant mothers. The status of HIV was collected from the records. Other variables were collected from the mothers using interviewer administered questionnaires. Logistic regression was used for the analysis. Adjusted Odds Ratios and their 95% Confidence Interval were calculated to determine association between HBsAg Sero-positivity and various factors. A p-value less than 0.05 were considered as significant. The data was analyzed using the SPSS version 25 statistical software. Results: Prevalence of hepatitis B virus among pregnant mothers was 9.2% in Gedio Zone. Previous birth at health institution [AOR=4.4, 95% CI: 1.7, 11.2], blood transfusions [AOR=4.4, 95% CI: 1.8, 10.5], previous history of Hospital admission [AOR=3.3, 95% CI: 1.5, 7.5], ear piercing practice [AOR=5.7, 95% CI: 1.1, 29.0], current Gestational age [AOR=3.6, 95% CI: 1.2, 11.2], and HIV status of the mother [AOR=6.1, 95% CI: 1.3, 30.0] had statistical significant association with HBsAg Sero-positivity.Conclusions: Hepatitis B virus infection was found to have higher endemicity (9.2%) in the Gedio Zone. History of blood transfusion, hospital admissions, ear piercing, being HIV positive, gestational age and institutional delivery were significant predictors for HBsAg sero-positivity. Early initiation of antenatal care service that integrate awareness creation about the risks of hepatitis B infection and mother to child transmission of the disease must be implemented by the health facilities in Gedio Zone.


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