Fatal toxic epidermal necrolysis in a patient on teriflunomide treatment for relapsing multiple sclerosis

2015 ◽  
Vol 21 (11) ◽  
pp. 1476-1477 ◽  
Author(s):  
Gaspard Gerschenfeld ◽  
Amandine Servy ◽  
Laurence Valeyrie-Allanore ◽  
Nicolas de Prost ◽  
Jérôme Cecchini
Keyword(s):  
Multiple Sclerosis ◽  
Drug Reaction ◽  
Toxic Epidermal Necrolysis ◽  
New Therapy ◽  
Relapsing Multiple Sclerosis ◽  
Cutaneous Drug Reaction

We report a case of toxic epidermal necrolysis in a 46-year-old woman on teriflunomide treatment. Such a severe adverse cutaneous drug reaction with this new therapy for relapsing forms of multiple sclerosis should be early recognized in order to ensure the rapid withdrawal of the drug.

Baclofen and trazodone: New culprits in toxic epidermal necrolysis

1996 ◽  
Vol 4 (2) ◽  
pp. 1-3
Author(s):  
N Sam Huq ◽  
Janet E Sproat
Keyword(s):  
Drug Reaction ◽  
Toxic Epidermal Necrolysis ◽  
Case Reports ◽  
Cutaneous Drug Reaction

Two case reports involving drugs suspected of causing toxic epidermal necrolysis, that have not been previously implicated in this rare cutaneous drug reaction, are presented.

scholarly journals Eczema herpeticum: A clinical diagnosis not to be missed

2020 ◽  
pp. 201010582097867
Author(s):  
Gabriel Hong Zhe Wong ◽  
Derrick Chen Wee Aw
Keyword(s):  
Atopic Dermatitis ◽  
Drug Reaction ◽  
Clinical Diagnosis ◽  
Skin Infection ◽  
Eczema Herpeticum ◽  
Cutaneous Drug Reaction ◽  
Uncommon Complication

Eczema herpeticum is an uncommon complication of atopic dermatitis, but often has a typical recognisable appearance. This report serves to highlight this feature in a patient who was misdiagnosed initially with a bacterial skin infection and then with a severe cutaneous drug reaction.

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