Are women disfavoured in the estimation of Disability Adjusted Life Years and the Global Burden of Disease?

AbstractBackground:CHDs are one of the most frequent congenital malformations, affecting one in hundred live births. In total, 70% will require treatment in the first year of life, but over 90% of cases in low- and middle-income countries receive no treatment or suboptimal treatment. As a result, CHDs are responsible for 66% of preventable deaths due to congenital malformations in low- and middle-income countries. This study examines the unmet need of congenital cardiac care around the world based on the global burden of disease.Materials and methods:CHD morbidity and mortality data for 2006, 2011, and 2016 were collected from the Institute for Health Metrics and Evaluation Global Burden of Disease Results Tool and analysed longitudinally to assess trends in excess morbidity and mortality.Results:Between 2006 and 2016, a 20.7% reduction in excess disability-adjusted life years and 20.6% reduction in excess deaths due to CHDs were observed for children under 15. In 2016, excess global morbidity and mortality due to CHDs remained high with 14,788,418.7 disability-adjusted life years and 171,761.8 paediatric deaths, respectively. In total, 90.2% of disability-adjusted life years and 91.2% of deaths were considered excess.Conclusion:This study illustrates the unmet need of congenital cardiac care around the world. Progress has been made to reduce morbidity and mortality due to CHDs but remains high and largely treatable around the world. Limited academic attention for global paediatric cardiac care magnifies the lack of progress in this area.

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Trends in the prevalence and disability-adjusted life years of eating disorders from 1990 to 2017: results from the Global Burden of Disease Study 2017

Epidemiology and Psychiatric Sciences ◽

10.1017/s2045796020001055 ◽

2020 ◽

Vol 29 ◽

Author(s):

Jiayuan Wu ◽

Jie Liu ◽

Shasha Li ◽

Huan Ma ◽

Yufeng Wang

Keyword(s):

Eating Disorders ◽

Burden Of Disease ◽

High Income ◽

Global Burden Of Disease ◽

Health Concern ◽

Global Burden ◽

Disability Adjusted Life Years ◽

Disability Adjusted Life ◽

Life Years ◽

Increasing Trend

Abstract Aim Eating disorders have increasingly become a public health concern globally. This study aimed to reveal the burden of eating disorders at the global, regional and national levels using the Global Burden of Disease (GBD) Study 2017 data. Methods We extracted the age-standardised rates (ASRs) of prevalence and disability-adjusted life years (DALYs) and their 95% uncertainty intervals (UIs) of eating disorders, including anorexia nervosa and bulimia nervosa, between 1990 and 2017 from the GBD 2017 data. The estimated annual percentage changes (EAPCs) were calculated to quantify the secular trends of the burden of eating disorders. Results The ASRs of prevalence and the DALYs of eating disorders continuously increased worldwide from 1990 to 2017 by an average of 0.65 (95% UI: 0.59–0.71) and 0.66 (95% UI: 0.60–0.72), respectively. The burden of eating disorders was higher in females than in males, but the increment in ASRs was greater in males than in females over time. In 2017, the highest burden of eating disorders was observed in the high sociodemographic index (SDI) regions, especially Australasia (ASR of prevalence = 807.13, 95% UI: 664.20–982.30; ASR of DALYs = 170.74, 95% UI: 113.43–244.14, per 100 000 population), Western Europe and high-income North America. However, the most significant increment of the burden of eating disorders was observed in East Asia (EAPC for prevalence = 2.23, 95% UI: 2.14–2.32; EAPC for DALYs = 2.22, 95% UI: 2.13–2.31), followed by South Asia. An increasing trend in the burden of eating disorders at the national level was observed among most countries or territories. The countries with the top three highest increasing trends were Equatorial Guinea, Bosnia and Herzegovina and China. Positive associations were found between the burden estimates and the SDI levels in almost all geographic regions during the observed 28-year period. We also found that the human development indexes in 2017 were positively correlated with the EAPCs of the ASRs of prevalence (ρ = 0.222, P = 0.002) and DALYs (ρ = 0.208, P = 0.003). Conclusion The highest burden of eating disorders remains in the high-income western countries, but an increasing trend was observed globally and in all SDI-quintiles, especially in Asian regions that were highly populous. These results could help governments worldwide formulate suitable medical and health policies for the prevention and early intervention of eating disorders.

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Diarrhoea deaths and disability-adjusted life years attributable to suboptimal breastfeeding practices in Nigeria: findings from the global burden of disease study 2016

International Breastfeeding Journal ◽

10.1186/s13006-019-0198-9 ◽

2019 ◽

Vol 14 (1) ◽

Cited By ~ 6

Author(s):

Felix Akpojene Ogbo ◽

Anselm Okoro ◽

Bolajoko O. Olusanya ◽

Jacob Olusanya ◽

Ifegwu K. Ifegwu ◽

...

Keyword(s):

Burden Of Disease ◽

Global Burden Of Disease ◽

Global Burden ◽

Disability Adjusted Life Years ◽

Breastfeeding Practices ◽

Disability Adjusted Life ◽

Life Years ◽

Disease Study ◽

Suboptimal Breastfeeding

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Global, regional and national burden of gout, 1990–2017: a systematic analysis of the Global Burden of Disease Study

Rheumatology ◽

10.1093/rheumatology/kez476 ◽

2019 ◽

Vol 59 (7) ◽

pp. 1529-1538 ◽

Cited By ~ 10

Author(s):

Yang Xia ◽

Qijun Wu ◽

Hanyuan Wang ◽

Shuang Zhang ◽

Yuting Jiang ◽

...

Keyword(s):

Burden Of Disease ◽

Global Burden Of Disease ◽

Global Burden ◽

Disability Adjusted Life Years ◽

Annual Percent Change ◽

Percent Change ◽

Disability Adjusted Life ◽

Life Years ◽

Study Results ◽

Disease Study

Abstract Objectives The burden of gout has been increasing globally. However, little is known about the global, regional and national distribution and time trend of this disease. We present a comprehensive analysis of the Global Burden of Disease Study 2017 on gout burden estimates for 195 countries or territories between 1990 and 2017. Methods Age-standardized prevalence and disability-adjusted life-years of gout were reported between 1990 and 2017 in 195 countries and territories, and associations between these estimates and sociodemographic index (SDI) were further explored. Total and annual percent change between 1990 and 2017 were calculated to quantify the time trends of gout burden. Results Age-standardized prevalence rates (95% uncertainty interval) per 100 000 persons were 790.90 (706.10–881.90) and 253.49 (225.69–284.02) in 2017 in males and females, respectively. The annual percent change in age-standardized prevalence (males, 0.22%; females, 0.38%) and disability-adjusted life-years (males, 0.21%; females, 0.38%) of gout increased every year from 1990 to 2017, globally. The highest increase was detected in high-SDI countries, especially in high-income North America. A non-linear association was observed between burden of gout and SDI, with the lowest estimates of gout burden when SDI value was about 0.6. High BMI was the leading risk factor for the burden of gout. Conclusion These study results suggest a globally rising trajectory of gout burden between 1990 and 2017. More effective interventions, such as detailed and intensive dietary managements and other prevention strategies for reducing obesity, should be carried out to reverse this trend, especially in females and high-SDI countries.

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The trend of incidence and burden of neurological disease in Iran between 1990 and 2017: Based on global burden of disease estimations

Iranian Journal of Neurology ◽

10.18502/ijnl.v18i3.1637 ◽

2019 ◽

Author(s):

Hedayat Abbastabar ◽

Sama Bitarafan ◽

Mohammad Hossein Harirchian

Keyword(s):

Burden Of Disease ◽

Neurological Disease ◽

Neurological Diseases ◽

Age Groups ◽

Global Burden Of Disease ◽

Global Burden ◽

Disability Adjusted Life Years ◽

Disability Adjusted Life ◽

Life Years ◽

Increasing Trend

Neurological disease contributes significantly to morbidity and mortality in different ages and geographic areas around the world. The purpose of the current study was to investigate the incidence and disability-adjusted life years (DALYs) trend of neurological disease in Iran during 27 years ago. We used the data of the Global Burden of Disease (GBD) Study to estimate the incidence and DALYs of neurological disease in Iran in different age groups between 1990 and 2017. Age groups were defined in 5 groups including < 5 years, 5-14 years, 15-49 years, 50-69 years, and ≥ 70 years. The incidence number of neurological disease during 1990 to 2017 increased from 7.5 million to more than 12 million and the incidence rate grew as much as 1400 per 100000 populations in Iran. Totally, headache, epilepsy, and Alzheimer were the most common neurological diseases according to incidence and had the most values of DALY in Iran. The highest incidence and DALY of neurological disease was observed in the age group of 15-49 years. This study showed that the incidence and burden of neurological diseases had a dramatic increasing trend during 27 years ago in Iran. Consequently, it is necessary to investigate the causes of the growing trend in future studies.

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