scholarly journals Locomotor Kinematics and Kinetics Following High-Intensity Stepping Training in Variable Contexts Poststroke

2020 ◽  
Vol 34 (7) ◽  
pp. 652-660
Author(s):  
Marzieh M. Ardestani ◽  
Christopher E. Henderson ◽  
Gordhan Mahtani ◽  
Mark Connolly ◽  
T. George Hornby
Keyword(s):  
High Intensity ◽  
Secondary Analysis ◽  
Principal Component ◽  
Joint Kinematics ◽  
Locomotor Training ◽  
Unique Identifier ◽  
Clinical Trial Registration ◽  
Paretic Limb ◽  
Principal Component Analyses ◽  
Kinematics And Kinetics

Background and Purpose. Previous studies suggest that individuals poststroke can achieve substantial gains in walking function following high-intensity locomotor training (LT). Recent findings also indicate practice of variable stepping tasks targeting locomotor deficits can mitigate selected impairments underlying reduced walking speeds. The goal of this study was to investigate alterations in locomotor biomechanics following 3 different LT paradigms. Methods. This secondary analysis of a randomized trial recruited individuals 18 to 85 years old and >6 months poststroke. We compared changes in spatiotemporal, joint kinematics, and kinetics following up to 30 sessions of high-intensity (>70% heart rate reserve [HRR]) LT of variable tasks targeting paretic limb and balance impairments (high-variable, HV), high-intensity LT focused only on forward walking (high-forward, HF), or low-intensity LT (<40% HRR) of variable tasks (low-variable, LV). Sagittal spatiotemporal and joint kinematics, and concentric joint powers were compared between groups. Regressions and principal component analyses were conducted to evaluate relative contributions or importance of biomechanical changes to between and within groups. Results. Biomechanical data were available on 50 participants who could walk ≥0.1 m/s on a motorized treadmill. Significant differences in spatiotemporal parameters, kinematic consistency, and kinetics were observed between HV and HF versus LV. Resultant principal component analyses were characterized by paretic powers and kinematic consistency following HV, while HF and LV were characterized by nonparetic powers. Conclusion. High-intensity LT results in greater changes in kinematics and kinetics as compared with lower-intensity interventions. The results may suggest greater paretic-limb contributions with high-intensity variable stepping training that targets specific biomechanical deficits. Clinical Trial Registration. https://clinicaltrials.gov/ Unique Identifier: NCT02507466

scholarly journals Treatment With Vasopressor Agents for Cardiovascular Shock Patients With Poor Renal Function; Results From the Japanese Circulation Society Cardiovascular Shock Registry

2021 ◽  
Vol 8 ◽  
Author(s):  
Tsukasa Yagi ◽  
Ken Nagao ◽  
Eizo Tachibana ◽  
Naohiro Yonemoto ◽  
Kazuo Sakamoto ◽  
...  
Keyword(s):  
Renal Function ◽  
Secondary Analysis ◽  
Disease Classification ◽  
First Line ◽  
Unique Identifier ◽  
Clinical Trial Registration ◽  
Hospital Arrival ◽  
Poor Renal Function ◽  
Vasopressor Agent ◽  
Vasopressor Agents

According to the guidelines for cardiogenic shock, norepinephrine is associated with fewer arrhythmias than dopamine and may be the better first-line vasopressor agent. This study aimed to evaluate the utility of norepinephrine vs. dopamine as first-line vasopressor agent for cardiovascular shock depending on the presence and severity of renal dysfunction at hospitalization. This was a secondary analysis of the prospective, multicenter Japanese Circulation Society Cardiovascular Shock Registry (JCS Shock Registry) conducted between 2012 and 2014, which included patients with shock complicating emergency cardiovascular disease at hospital arrival. The analysis included 240 adult patients treated with norepinephrine alone (n = 98) or dopamine alone (n = 142) as the first-line vasopressor agent. Primary endpoint was mortality at 30 days after hospital arrival. The two groups had similar baseline characteristics, including estimated glomerular filtration rate (eGFR), and similar 30-day mortality rates. The analysis of the relationship between 30-day mortality rate after hospital arrival and vasopressor agent used in patients categorized according to the eGFR-based chronic kidney disease classification revealed that norepinephrine as the first-line vasopressor agent might be associated with better prognosis of cardiovascular shock in patients with mildly compromised renal function at admission (0.0 vs. 22.6%; P = 0.010) and that dopamine as the first-line vasopressor agent might be beneficial for cardiovascular shock in patients with severely compromised renal function [odds ratio; 0.22 (95% confidence interval 0.05–0.88; P = 0.032)]. Choice of first-line vasopressor agent should be based on renal function at hospital arrival for patients in cardiovascular shock.Clinical Trial Registration:http://www.umin.ac.jp/ctr/, Unique identifier: 000008441.

scholarly journals Fast diffusion kurtosis mapping of human brain at 7 Tesla with hybrid principal component analyses

IEEE Access ◽  
2021 ◽  
pp. 1-1
Author(s):  
Fangrong Zong ◽  
Jiaxin Du ◽  
Xiaofeng Deng ◽  
Xubin Chai ◽  
Yan Zhuo ◽  
...  
Keyword(s):  
Human Brain ◽  
Principal Component ◽  
7 Tesla ◽  
Fast Diffusion ◽  
Principal Component Analyses ◽  
Diffusion Kurtosis

scholarly journals The Effects of Repetitive Drop Jumps on Impact Phase Joint Kinematics and Kinetics

2011 ◽  
Vol 27 (2) ◽  
pp. 108-115 ◽  
Author(s):  
Joshua T. Weinhandl ◽  
Jeremy D. Smith ◽  
Eric L. Dugan
Keyword(s):  
Energy Absorption ◽  
Plantar Flexion ◽  
Knee Extension ◽  
Joint Kinematics ◽  
Knee Extensors ◽  
Initial Contact ◽  
Drop Jumps ◽  
Impact Phase ◽  
The Impact ◽  
Kinematics And Kinetics

The purpose of the study was to investigate the effects of fatigue on lower extremity joint kinematics, and kinetics during repetitive drop jumps. Twelve recreationally active males (n= 6) and females (n= 6) (nine used for analysis) performed repetitive drop jumps until they could no longer reach 80% of their initial drop jump height. Kinematic and kinetic variables were assessed during the impact phase (100 ms) of all jumps. Fatigued landings were performed with increased knee extension, and ankle plantar flexion at initial contact, as well as increased ankle range of motion during the impact phase. Fatigue also resulted in increased peak ankle power absorption and increased energy absorption at the ankle. This was accompanied by an approximately equal reduction in energy absorption at the knee. While the knee extensors were the muscle group primarily responsible for absorbing the impact, individuals compensated for increased knee extension when fatigued by an increased use of the ankle plantar flexors to help absorb the forces during impact. Thus, as fatigue set in and individuals landed with more extended lower extremities, they adopted a landing strategy that shifted a greater burden to the ankle for absorbing the kinetic energy of the impact.

scholarly journals The Importance of Being Earnest about Shank and Thigh Kinematics Especially When Using Ankle-Foot Orthoses

2010 ◽  
Vol 34 (3) ◽  
pp. 254-269 ◽  
Author(s):  
Elaine Owen
Keyword(s):  
Joint Kinematics ◽  
Foot Orthoses ◽  
Traditional Beliefs ◽  
Vertical Angle ◽  
Gait Biomechanics ◽  
Normal Gait ◽  
Ankle Foot Orthoses ◽  
Pathological Gait ◽  
Kinematics And Kinetics

This paper reviews and summarizes the evidence for important observations of normal and pathological gait and presents an approach to rehabilitation and orthotic management, which is based on the significance of shank and thigh kinematics for standing and gait. It discusses normal gait biomechanics, challenging some traditional beliefs, the interrelationship between segment kinematics, joint kinematics and kinetics and their relationship to orthotic design, alignment and tuning. It proposes a description of four rather than three rockers in gait; a simple categorization of pathological gait based on shank kinematics abnormality; an algorithm for the designing, aligning and tuning of AFO-Footwear Combinations; and an algorithm for determining the sagittal angle of the ankle in an AFO. It reports the results of research on Shank to Vertical Angle alignment of tuned AFO-Footwear Combinations and on the use of ‘point loading’ rocker soles.

scholarly journals Influence of biomechanical models on joint kinematics and kinetics in baseball pitching

2018 ◽  
pp. 1-13
Author(s):  
Xavier Gasparutto ◽  
Erik van der Graaff ◽  
Frans C. T. van der Helm ◽  
Dirkjan H. E. J. Veeger
Keyword(s):  
Joint Kinematics ◽  
Biomechanical Models ◽  
Kinematics And Kinetics
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