scholarly journals Enhanced Histochemical Detection of Iron in Paraffin Sections of Mouse Central Nervous System Tissue

ASN NEURO ◽  
2016 ◽  
Vol 8 (5) ◽  
pp. 175909141667097 ◽  
Author(s):  
Scott A. Sands ◽  
Regis Leung-Toung ◽  
Yingsheng Wang ◽  
John Connelly ◽  
Steven M. LeVine
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Central Nervous System Tissue ◽  
Paraffin Sections ◽  
Histochemical Detection ◽  
Mouse Central Nervous System

Myelination by transplanted human and mouse central nervous system tissue after long-term cryopreservation

1995 ◽  
Vol 91 (1) ◽  
pp. 82-88 ◽  
Author(s):  
D. Seilhean ◽  
A. Gansmüller ◽  
A. Baron-Van Evercooren ◽  
M. Gumpel ◽  
F. Lachapelle
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Central Nervous System Tissue ◽  
Human And Mouse ◽  
Mouse Central Nervous System

Confocal laser microscopy of impregnated central nervous system tissue

1988 ◽  
Vol 46 ◽  
pp. 94-95
Author(s):  
J.N. Turner ◽  
M. Siemens ◽  
D. Szarowski ◽  
D.N. Collins
Keyword(s):  
Electron Microscopy ◽  
Central Nervous System ◽  
Nervous System ◽  
Three Dimensional ◽  
Dimensional Structure ◽  
Confocal Laser ◽  
High Contrast ◽  
Central Nervous System Tissue ◽  
Tissue Samples ◽  
Reflected Light

A classic preparation of central nervous system tissue (CNS) is the Golgi procedure popularized by Cajal. The method is partially specific as only a few cells are impregnated with silver chromate usualy after osmium post fixation. Samples are observable by light (LM) or electron microscopy (EM). However, the impregnation is often so dense that structures are masked in EM, and the osmium background may be undesirable in LM. Gold toning is used for a subtle but high contrast EM preparation, and osmium can be omitted for LM. We are investigating these preparations as part of a study to develop correlative LM and EM (particularly HVEM) methodologies in neurobiology. Confocal light microscopy is particularly useful as the impregnated cells have extensive three-dimensional structure in tissue samples from one to several hundred micrometers thick. Boyde has observed similar preparations in the tandem scanning reflected light microscope (TSRLM).

scholarly journals CB1 and LPA1 Receptors Relationship in the Mouse Central Nervous System

2019 ◽  
Vol 12 ◽  
Author(s):  
Estíbaliz González de San Román ◽  
Iván Manuel ◽  
Catherine Ledent ◽  
Jerold Chun ◽  
Fernando Rodríguez de Fonseca ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Mouse Central Nervous System

scholarly journals Apoptotic Cells, Including Macrophages, Are Prominent in Theiler's Virus-Induced Inflammatory, Demyelinating Lesions

2003 ◽  
Vol 77 (7) ◽  
pp. 4383-4388 ◽  
Author(s):  
Brian P. Schlitt ◽  
Matthew Felrice ◽  
Mary Lou Jelachich ◽  
Howard L. Lipton
Keyword(s):  
Central Nervous System ◽  
T Cells ◽  
Nervous System ◽  
In Situ Hybridization ◽  
Apoptotic Cells ◽  
Theiler's Virus ◽  
Demyelinating Lesions ◽  
Encephalomyelitis Virus ◽  
Mouse Central Nervous System

ABSTRACT Theiler's murine encephalomyelitis virus (TMEV) persists in the mouse central nervous system principally in macrophages, and infected macrophages in culture undergo apoptosis. We have detected abundant apoptotic cells in perivascular cuffs and inflammatory, demyelinating lesions of SJL mice chronically infected with TMEV. T cells comprised 74% of apoptotic cells, while 8% were macrophages, 0.6% were astrocytes, and ∼17% remained unidentified. In situ hybridization revealed viral RNA in ∼1% of apoptotic cells.

scholarly journals Targeted DNA transfection into the mouse central nervous system using laser-induced stress waves

2005 ◽  
Vol 10 (6) ◽  
pp. 060501 ◽  
Author(s):  
Yasushi Satoh ◽  
Yasunari Kanda ◽  
Mitsuhiro Terakawa ◽  
Minoru Obara ◽  
Katsushige Mizuno ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Stress Waves ◽  
Dna Transfection ◽  
Induced Stress ◽  
Mouse Central Nervous System

HISTOPATHOLOGY OF MULTIPLE SCLEROSIS LESIONS DETECTED BY MAGNETIC RESONANCE IMAGING IN UNFIXED POSTMORTEM CENTRAL NERVOUS SYSTEM TISSUE

Brain ◽  
1991 ◽  
Vol 114 (2) ◽  
pp. 1013-1023 ◽  
Author(s):  
J. NEWCOMBE ◽  
C. P. HAWKINS ◽  
C. L. HENDERSON ◽  
H. A. PATEL ◽  
M. N. WOODROOFE ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Multiple Sclerosis ◽  
Central Nervous System ◽  
Nervous System ◽  
Magnetic Resonance ◽  
Resonance Imaging ◽  
Central Nervous System Tissue

Rapid test for the preclinical postmortem diagnosis of BSE in central nervous system tissue

2001 ◽  
Vol 149 (19) ◽  
pp. 577-582 ◽  
Author(s):  
J. Grassi ◽  
S. Simon ◽  
C. Crminon ◽  
Y. Frobert ◽  
E. Comoy ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Rapid Test ◽  
Central Nervous System Tissue ◽  
Postmortem Diagnosis
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