Chemical Composition and Anti-mildew Activities of Essential Oils from Different Parts of Michelia compressa var. formosana

In this study, anti-mildew activities of the essential oils of the leaves, wood, twigs, flowers, and their constituents from Michelia compressa var. formosana were evaluated in vitro against 7 mildew fungi. The main compounds responsible for the anti-mildew activities were isolated and identified. The essential oils from the fresh leaves, wood, twigs, and flowers of M. compressa var. formosana were isolated using hydrodistillation in a Clevenger-type apparatus, and characterized by GC-FID and GC-MS. The essential oil yield from the flowers was the highest, and the oils obtained from the 4 parts of the tree were composed mainly of sesquiterpenoids. The leaf oil consisted primarily of α-cadinol (18.9%) and germacrene D (18.5%); the twig oil's main constituent was α-cadinol (19.1%); the wood oil's major components were α-cadinol (25.7%) and β-eudesmol (20.2%); and the flower oil contained α-cadinol (11.4%). Comparing the anti-mildew activities of the oils suggested that wood oil was the most effective. Further fractionation of the wood oil produced α-cadinol, β-eudesmol, τ-cadinol, and elemol. The 4 compounds exhibit very strong anti-mildew activities, and these in descending order are α-cadinol, elemol, β-eudesmol, and τ-cadinol. For the anti-mildew activities of the wood oil, the active source compounds were determined to be α-cadinol, elemol, β-eudesmol, and τ-cadinol.

Download Full-text

Essential Oil Constituents of Etlingera yunnanensis and Hornstedtia sanhan grown in Vietnam

Natural Product Communications ◽

10.1177/1934578x1501000240 ◽

2015 ◽

Vol 10 (2) ◽

pp. 1934578X1501000 ◽

Cited By ~ 1

Author(s):

Dao T. M. Chau ◽

Do N. Dai ◽

Tran M. Hoi ◽

Tran H. Thai ◽

Tran D. Thang ◽

...

Keyword(s):

Mass Spectrometry ◽

Gas Chromatography ◽

Chemical Composition ◽

Essential Oil ◽

Ionization Detector ◽

Methyl Chavicol ◽

Flame Ionization ◽

Germacrene D ◽

Leaf Oil ◽

Different Parts

The chemical composition of the essential oils obtained from the hydrodistillation of different parts of Etlingera yunnanensis (T.L. Wu &S.J. Chen) R.M. Sm. and Hornstedtia sanhan M.F. Newman (Zingiberaceae) grown in Vietnam are reported. The analysis was performed by means of a gas chromatography-flame ionization detector (GC-FID) and gas chromatography coupled with mass spectrometry (GC-MS). The essential oil of the leaves of E. yunnanensis comprised mainly germacrene D (19.2%), β-pinene (11.6%), and α-amorphene (11.2%), while that of the stems was rich in β-pinene (23.7%), 1,8-cineole (11.0%) and α-pinene (9.6%). The major components of the root oil of E. yunnanensis were β-pinene (31.9%), α-pinene (13.7%) and 1,8-cineole (9.4%). However, α-pinene (25.9%, 36.3% and 14.1% for leaves, stems and roots, respectively), β-pinene (9.7%, 11.8% and 7.2% for leaves, stems and roots, respectively) and limonene (22.1%, 24.6% and 16.2% for leaves, stems and roots, respectively) were the major compounds of H. sanhan. In addition, α-humulene (15.9%) was present in larger amounts in the leaf oil while the root oil contained the largest proportion of methyl chavicol (43.7%).

Download Full-text

Composition and in vitro Anticancer Activities of the Leaf Essential Oil of Neolitsea variabillima from Taiwan

Natural Product Communications ◽

10.1177/1934578x1300800432 ◽

2013 ◽

Vol 8 (4) ◽

pp. 1934578X1300800 ◽

Cited By ~ 2

Author(s):

Yu-Chang Su ◽

Kuan-Ping Hsu ◽

Eugene I-Chen Wang ◽

Chen-Lung Ho

Keyword(s):

Chemical Composition ◽

Essential Oil ◽

Cytotoxic Activity ◽

Cancer Cells ◽

Anticancer Activities ◽

Leaf Oil ◽

Leaf Essential Oil ◽

Main Components ◽

Type Apparatus

This study investigated the chemical composition and in vitro anticancer activities of the essential oil isolated from the leaf of Neolitsea variabillima. The essential oil was isolated using hydrodistillation in a Clevenger-type apparatus, and characterized by GC-FID and GC-MS. Sixty-seven compounds were identified, representing 100% of the oil. The main components identified were trans-β-ocimene (13.4%), α-cadinol (10.5%), terpinen-4-ol (9.3%), τ-cadinol (9.2%), β-caryophyllene (8.8%), and sabinene (6.7%). The anticancer activities of oil were evaluated. The results showed that the oil exhibited cytotoxic activity against human oral, liver, lung, colon, melanoma, and leukemic cancer cells. The presence of β-caryophyllene, τ-cadinol, and α-cadinol significantly contributed to the anticancer activities of N. variabillima leaf oil.

Download Full-text

Chemical Compositions and In Vitro Antiphytopathogenic Fungi Activities of the Leaf and Cones Essential Oils of Cunninghamia lanceolata From Taiwan

Natural Product Communications ◽

10.1177/1934578x20936971 ◽

2020 ◽

Vol 15 (8) ◽

pp. 1934578X2093697

Author(s):

Kuang-Ping Hsu ◽

Yu-Chang Su ◽

Chen-Lung Ho

Keyword(s):

Essential Oil ◽

Essential Oils ◽

Pathogenic Fungi ◽

Cunninghamia Lanceolata ◽

Chemical Compositions ◽

Plant Pathogenic Fungi ◽

Active Source ◽

Leaf Oil ◽

Type Apparatus

In this study, antiphytopathogenic fungi activities of the leaf and cones essential oils and its constituents from Cunninghamia lanceolata were evaluated in vitro against 6 plant pathogenic fungi. The main compounds responsible for the antiphytopathogenic fungi activities were isolated and identified. The essential oil from the fresh leaves and cones of C. lanceolata was isolated using hydrodistillation in a Clevenger-type apparatus, and characterized by GC-FID and GC-MS, respectively. The leaf oil consisted primarily of ferruginol (10%), τ-cadinol (8.2%), and α-cadinol (6.6%); the cones oil’s main constituents were abietadiene (42.5%), abietatriene (13.1%), and α-pinene (9.6%). Comparing the antiphytopathogenic fungi activities of the oils suggested that leaf oil was the most effective one. Further fractionation of the leaf oil produced ferruginol, τ-cadinol, and α-cadinol. The 3 compounds exhibited very strong antiphytopathogenic fungi activities. For the antiphytopathogenic fungi activities of the leaf oil, the active source compounds were determined to be ferruginol, τ-cadinol, and α-cadinol.

Download Full-text

Composition, in vitro Antibacterial and Anti-mildew Fungal Activities of Essential Oils from Twig and Fruit Parts of Eucalyptus citriodora

Natural Product Communications ◽

10.1177/1934578x1701201031 ◽

2017 ◽

Vol 12 (10) ◽

pp. 1934578X1701201

Author(s):

Yu-Chang Su ◽

Kuang-Ping Hsu ◽

Chen-Lung Ho

Keyword(s):

Essential Oil ◽

Essential Oils ◽

Caryophyllene Oxide ◽

Main Constituent ◽

Eucalyptus Citriodora ◽

Active Source ◽

Fruit Oil ◽

Type Apparatus

In this study, antibacterial and anti-mildew fungal activities of the twig and fruit essential oil and its constituents from Eucalyptus citriodora were investigated in vitro against eight bacteria and seven mildew fungi, respectively. The major ingredient responsible for the antibacterial and anti-mildew fungal activities were also identified. The essential oil from the fresh twigs and fruits of E. citriodora were isolated using hydrodistillation in a Clevenger-type apparatus, and characterized by GC–FID and GC–MS, respectively. The twig oil consisted primarily of 1,8-cineole (17.7%), p-cymene (17.1%), caryophyllene oxide (13.8%), and isopulegol (12.2%); the fruit oil's main constituent was p-cymene (23.2%), α-pinene (16.1%), α-cadinol (11.5%), and τ-cadinol (8.4%). In addition, comparing the antibacterial and anti-mildew fungal activities of the oils showed that the fruit oil was the most effective. For the antibacterial and anti-mildew fungal activities of the fruit oil, the active source compounds were determined to be τ-cadinol and τ-cadinol.

Download Full-text

Chemical Composition and Anti-Trypanosoma cruzi Activity of Essential Oils Obtained from Leaves of Xylopia frutescens and X. laevigata (Annonaceae)

Natural Product Communications ◽

10.1177/1934578x1300800332 ◽

2013 ◽

Vol 8 (3) ◽

pp. 1934578X1300800 ◽

Cited By ~ 5

Author(s):

Thanany Brasil da Silva ◽

Leociley Rocha Alencar Menezes ◽

Marília Fernanda Chaves Sampaio ◽

Cássio Santana Meira ◽

Elisalva Teixeira Guimarães ◽

...

Keyword(s):

Chemical Composition ◽

Trypanosoma Cruzi ◽

Essential Oils ◽

Trypanocidal Activity ◽

Germacrene D ◽

Main Components ◽

Type Apparatus

Essential oils from leaves of Xylopia frutescens (XFMJ) and two specimens of Xylopia laevigata (XLMC and XLSI) were obtained by hydrodistillation using a Clevenger-type apparatus, and analyzed by GC-MS and GC-FID. Sesquiterpenes dominated the essential oils. The main constituents of XFMJ were ( E)-caryophyllene (24.8%), bicyclogermacrene (20.8%), germacrene D (17.0%), β-elemene (7.9%), and ( E)-β-ocimene (6.8%). XLMC contained significant quantities of germacrene D (18.9%), bicyclogermacrene (18.4%), β-elemene (9.5%), 5-selinene (9.2%), ( E)-caryophyllene (8.5%), germacrene B (5.7%) and γ-muurolene (5.7%), while germacrene D (27.0%), bicyclogermacrene (12.8%), ( E)-caryophyllene (8.6%), γ-muurolene (8.6%), 5-cadinene (6.8%), and germacrene B (6.0%) were the main components of XLSI. The essential oils had trypanocidal activity against the Y strain of Trypanosoma cruzi. with IC50 values lower than 30 μg.mL−1 and 15 μg.mL−1 against epimastigote and trypomastigote forms of T. cruzi. respectively, and were also able to reduce the percentage in vitro of T. cruzi-infected macrophages and the intracellular number of amastigotes at concentrations that were non-cytotoxic to macrophages.

Download Full-text

Essential Oil Compositions and Cytotoxic Activities of Dendropanax capillaris, Oreopanax Nubigenus, and Schefflera Rodrigueziana from Monteverde, Costa Rica

Natural Product Communications ◽

10.1177/1934578x0900400221 ◽

2009 ◽

Vol 4 (2) ◽

pp. 1934578X0900400 ◽

Cited By ~ 4

Author(s):

Justin D. Richmond ◽

Brittany R. Agius ◽

Brenda S. Wright ◽

William A. Haber ◽

Debra M. Moriarity ◽

...

Keyword(s):

Costa Rica ◽

Essential Oil ◽

Essential Oils ◽

In Vitro Cytotoxicity ◽

Cytotoxic Activities ◽

Sesquiterpene Hydrocarbons ◽

Germacrene D ◽

Leaf Oil ◽

High Concentrations

The leaf essential oils of Dendropanax capillaris, Oreopanax nubigenus and Schefflera rodrigueziana (Araliaceae) were isolated by hydrodistillation and analyzed by GC-MS. The leaf oil of Dendropanax capillaris was composed of only four compounds, β-pinene (25.3%), δ-3-carene (44.7%), daucene (17.1%), and dauca-5,8-diene (12.9%). Oreopanax nubigenus leaf oil was dominated by the sesquiterpene hydrocarbons germacrene D (70.1%) and β-caryophyllene (11.8%), while Schefflera rodrigueziana leaf oil was made up entirely of sesquiterpene hydrocarbons, mostly germacrene D (27.6%), β-cubebene (27.2%), β-caryophyllene (12.2%), α-cubebene (11.1%), and α-copaene (10.8%). Both O. nubigenus and S. rodrigueziana leaf oils showed notable in-vitro cytotoxicity on MDA-MB-231 cells, which may be attributable to the relatively high concentrations of germacrene D and β-caryophyllene in those oils.

Download Full-text

Chemical Composition and Cytotoxic Activity of the Leaf Essential Oil of Ocotea tonduzii from Monteverde, Costa Rica

Natural Product Communications ◽

10.1177/1934578x0700200716 ◽

2007 ◽

Vol 2 (7) ◽

pp. 1934578X0700200 ◽

Cited By ~ 9

Author(s):

Anita Bansal ◽

Debra M. Moriarity ◽

Sayaka Takaku ◽

William N. Setzer

Keyword(s):

Costa Rica ◽

Chemical Composition ◽

Essential Oil ◽

Cytotoxic Activities ◽

Germacrene D ◽

Leaf Oil ◽

Leaf Essential Oil ◽

Oil Components ◽

Mcf 7

The leaf essential oil of Ocotea tonduzii from Monteverde, Costa Rica has been obtained by hydrodistillation and analyzed by GC-MS. The principal constituents of O. tonduzii leaf oil were the monoterpenes α-pinene (41.4%) and pinene (25.1%) and the sesquiterpenes α-humulene (6.9%), β-caryophyllene (5.8%), and germacrene D (3.8%). O. tonduzii leaf oil was notably cytotoxic on MCF-7, MDA-MB-231, MDA-MB-468, and UACC-257 cells in vitro. The major essential oil components showed cytotoxic activities comparable to doxorubicin ( LC50, 20–70 μg/mL).

Download Full-text

Composition, in vitro Cytotoxicity, and Anti-mildew Activities of the Leaf Essential Oil of Machilus thunbergii from Taiwan

Natural Product Communications ◽

10.1177/1934578x1501001153 ◽

2015 ◽

Vol 10 (11) ◽

pp. 1934578X1501001

Author(s):

Yu-Chang Su ◽

Kuan-Ping Hsu ◽

Shu-Ching Li ◽

Chen-Lung Ho

Keyword(s):

Chemical Composition ◽

Essential Oil ◽

In Vitro Cytotoxicity ◽

Active Source ◽

Leaf Oil ◽

Machilus Thunbergii ◽

Leaf Essential Oil ◽

Main Components ◽

Type Apparatus

This study investigated the chemical composition, in-vitro cytotoxicity, and anti-mildew fungal activities of the essential oil isolated from the leaf of Machilus thunbergii from Taiwan. The essential oil was isolated using hydrodistillation in a Clevenger-type apparatus, and characterized by GC–FID and GC–MS. Eighty-three compounds were identified, representing 99.8% of the oil. The main components identified were n-decanal (26.6%), β-caryophyllene (15.8%), α-humulene (10.8%), and β-eudesmol (10.5%). The oil exhibited cytotoxic activity against human oral, liver, lung, colon, melanoma, and leukemic cancer cells. The active source compounds were β-caryophyllene, α-humulene, and β-eudesmol. The anti-mildew activity of the leaf oil was also evaluated. Results showed that the leaf oil had excellent anti-mildew activity. For the anti-mildew activity of the leaf oil, the active source compound was determined to be β-eudesmol.

Download Full-text

Chemical Composition of the Essential Oils of Some Central Asian Nepeta Species (Lamiaceae) by GLC-MS

Natural Product Communications ◽

10.1177/1934578x1601101229 ◽

2016 ◽

Vol 11 (12) ◽

pp. 1934578X1601101

Author(s):

Nilufar Z. Mamadalieva ◽

Farukh S. Sharopov ◽

Prabodh Satyal ◽

Shahnoz S. Azimova ◽

Michael Wink

Keyword(s):

Chemical Composition ◽

Essential Oil ◽

Essential Oils ◽

Radical Scavenging Activity ◽

Radical Scavenging ◽

Free Radical Scavenging ◽

Aerial Parts ◽

Central Asian ◽

Germacrene D

The chemical composition of the essential oils obtained from aerial parts of Nepeta alatavica Lipsky, N. nuda L., and N. olgae Regel (Lamiaceae), growing wild in Central Asia (Tajikistan and Uzbekistan), were analyzed by GLC and GLC-MS. The main constituents of the essential oil from N. nuda were 1,8-cineole (24.6%), 4a-α,7-β,7a-α-nepetalactone (21.0%), germacrene D (13.5%), and β-caryophyllene (12.7%), whereas those of N. alatavica were thymol (48.5%), verbenone (7.7%), and carvacrol (7.5%). In the essential oil of N. olgae the most abundant compounds were acetylcyclohexene (31.5%), 4-tridecyne (13.2%), 2-methyl cyclopentanone (6.8%) and 1,8-cineole (6.0%). The potential antioxidant activity of these essential oils was studied by using DPPH, ABTS and FRAP assays. The essential oil of N. alatavica showed the highest in vitro free radical scavenging activity, probably due to its high thymol and carvacrol content.

Download Full-text

Tephrosia Toxicaria Pers Essential Oil: Chemical Composition and Larvicidal Activity

Natural Product Communications ◽

10.1177/1934578x0600100509 ◽

2006 ◽

Vol 1 (5) ◽

pp. 1934578X0600100 ◽

Cited By ~ 1

Author(s):

Walber H. F. Ribeiro ◽

Jackson N. Vasconcelos ◽

Angela M. C. Arriaga ◽

Maria C. F. de Oliveira ◽

Manoel Andrade-Neto ◽

...

Keyword(s):

Chemical Composition ◽

Essential Oil ◽

Aedes Aegypti ◽

Essential Oils ◽

Larvicidal Activity ◽

Mosquito Larvae ◽

Main Constituent ◽

Germacrene D

The essential oils obtained by hydrodistillation of the leaves, stems, and shoots of Tephrosia toxicaria Pers (Papilionaceae) were analyzed using GC and GC/MS. Germacrene D was the major component (20.7-33.3 %) of the oils of leaves and shoots, whereas spathulenol was the main constituent (42.3%) of the stem oil. The essential oils from the leaves and stems, when tested for activity against mosquito larvae (Aedes aegypti), gave LC 50 values of 81.3 ± 2.9 and 63.1 ± 1.0 ppm, respectively.

Download Full-text