scholarly journals Lignans from the Whole Plants of Hedyotis uncinella

2016 ◽  
Vol 11 (8) ◽  
pp. 1934578X1601100
Author(s):  
Yaping Pan ◽  
Yan Zhang ◽  
Chao Fan ◽  
Yu Zhang ◽  
Shikai Yan ◽  
...  
Keyword(s):  
2D Nmr ◽  
Esi Ms ◽  
H Nmr ◽  
Whole Plants ◽  
C Nmr

Two new lignans, named (7R, 8 S)-balanophonin (1) and (7R, 8 S)-tomentosanan A (2), together with eight known lignans, burselignan (3), (+)-isolariciresinol (4), (+)-lyoniresinol (5), 5-methoxy-(+)-isolariciresinol (6), (-)-syringaresinol (7), (+)-epipinoresinol (8), (-)-(7′ S, 8 S, 8′ R)-4,4′-dihydroxy-3, 3′, 5, 5′-tetramethoxy-7, 9-epoxy-lignan-9′-ol-7-one (9), and (-)-(7 R, 8 S)-dihydrodehydrodiconiferyl alcohol (10) were isolated from the whole plants of Hedyotis uncinella Hook. et Arn. Structures of these compounds were elucidated through 1H NMR, 13C NMR, 2D NMR, ESI-MS and CD data.

Flavonoids from Achillea nobilis L.

2003 ◽  
Vol 58 (1-2) ◽  
pp. 11-16 ◽  
Author(s):  
Liselotte Krenn ◽  
Anca Miron ◽  
Enne Pemp ◽  
Ursula Petr ◽  
Brigitte Kopp
Keyword(s):  
Methyl Ether ◽  
Methanolic Extract ◽  
2D Nmr ◽  
Spectroscopic Methods ◽  
Esi Ms ◽  
H Nmr ◽  
Aerial Parts ◽  
Nmr Techniques ◽  
C Nmr

The detailed investigation of a methanolic extract of aerial parts of Achillea nobilis resulted in the isolation of 10 flavonoids. A new C-glycosylflavone, luteolin-6-C-apiofuranosyl-(1‴→2″)-glucoside, was isolated besides orientin, isoorientin, vitexin, isoschaftoside, luteolin- 7-O-β-glucuronide, luteolin-4′-O-β-glucoside and quercetin-3-O-methyl ether and two rare flavonolglycosides, quercetin-3-O-α-arabinosyl-(1‴→6″ )-glucoside and quercetin-3-O-methylether-7-O-β-glucoside. The structures were established either by comparison with authentic substances or by UV, 1H NMR and 13C NMR spectroscopic methods including 2ᴅ-NMR techniques and ESI-MS

Flavon- and Flavonolglycosides from Achillea pannonica Scheele

2001 ◽  
Vol 56 (7-8) ◽  
pp. 521-525 ◽  
Author(s):  
Denata Kasaj ◽  
Liselotte Krenn ◽  
Sonja Prinz ◽  
Antje Hüfner ◽  
Shi Shan Yuc ◽  
...  
Keyword(s):  
Methanolic Extract ◽  
2D Nmr ◽  
Flavonoid Glycosides ◽  
Spectroscopic Methods ◽  
Esi Ms ◽  
Aerial Parts ◽  
Nmr Techniques ◽  
Chemotaxonomic Study ◽  
First Time ◽  
C Nmr

The detailed investigation of a methanolic extract of aerial parts of Achillea pannonica SCHEELE. within a chemotaxonomic study led to the isolation of 6 flavonoid glycosides. Besides rutin, apigenin-7-O-glucopyranoside, luteolin-7-O-glucopyranoside, apigenin-7-O-rutinoside and acacetin-7-O-rutinoside, an unusual flavondiglucoside was isolated. Its structure was established by UV, 1HNMR and 13C NMR spectroscopic methods including 2D-NMR techniques and ESI-MS as luteolin-7,4′-O-β-diglucoside. This substance is reported for the first time in the genus Achillea. Chemotaxonomic aspects are discussed briefly

E-Homolupane Derivatives Substituted in Position 17 and 22a. 1H NMR, 13C NMR and IR Spectra

1995 ◽  
Vol 60 (4) ◽  
pp. 619-635 ◽  
Author(s):  
Václav Křeček ◽  
Stanislav Hilgard ◽  
Miloš Buděšínský ◽  
Alois Vystrčil
Keyword(s):  
Nmr Spectra ◽  
2D Nmr ◽  
Coupling Constants ◽  
Side Chain ◽  
Oxidation Reactions ◽  
H Nmr ◽  
Complete Assignment ◽  
Nmr Techniques ◽  
Intramolecular Association ◽  
C Nmr

A series of derivatives with various oxygen functionalities in positions 17,22a or 19,20 was prepared from diene I and olefin XVI by addition and oxidation reactions. The structure of the obtained compounds was confirmed by 1H NMR, 13C NMR and IR spectroscopy. The kind of intramolecular association of the 17α-hydroxy group was studied in connection with modification of the side chain and substitution in position 22a. Complete assignment of the hydrogen signals and most of the coupling constants was accomplished using a combination of 1D and 2D NMR techniques. The 1H and 13C NMR spectra are discussed.

scholarly journals Two New Glycosides from Conyza bonariensis

2010 ◽  
Vol 5 (7) ◽  
pp. 1934578X1000500 ◽  
Author(s):  
Aqib Zahoor ◽  
Imran Nafees Siddiqui ◽  
Afsar Khan ◽  
Viqar Uddin Ahmad ◽  
Amir Ahmed ◽  
...  
Keyword(s):  
2D Nmr ◽  
Mass Spectrometric ◽  
Spectroscopic Techniques ◽  
H Nmr ◽  
Alkyl Glycoside ◽  
Conyza Bonariensis ◽  
C Nmr

Studies on Conyza bonariensis (L.) Cronq. led to the isolation of two new glycosides trivially named as erigeside E and F (1–2), along with two new source compounds; benzyl-β-D-glucopyranoside (3) and 2-phenylethyl-β-D-glucopyranoside (4). Compounds 1, 3, and 4 are aromatic glycosides, while compound 2 is an alkyl glycoside. Their structures were elucidated through mass spectrometric, and 1D- and 2D-NMR spectroscopic techniques, including 1H NMR, 13C NMR, HMQC, HSQC and HMBC.

scholarly journals Reactions of 3-(p-substituted-phenyl)-5-chloromethyl-1,2,4-oxadiazoles with KCN leading to acetonitriles and alkanes via a non-reductive decyanation pathway

2018 ◽  
Vol 14 ◽  
pp. 3011-3017
Author(s):  
Akın Sağırlı ◽  
Yaşar Dürüst
Keyword(s):  
Nmr Spectra ◽  
2D Nmr ◽  
Synthetic Route ◽  
X Ray ◽  
H Nmr ◽  
2D Nmr Spectra ◽  
Tof Ms ◽  
C Nmr

The present work describes an unfamiliar reaction of 5-(chloromethyl)-3-substituted-phenyl-1,2,4-oxadiazoles with KCN affording trisubstituted 1,2,4-oxadiazol-5-ylacetonitriles and their parent alkanes, namely, 1,2,3-trisubstituted-1,2,4-oxadiazol-5-ylpropanes. To the best of our knowledge, the current synthetic route leading to decyanated products will be the first in terms of a decyanation process which allows the transformation of trisubstituted acetonitriles into alkanes by the incorporation of KCN with the association of in situ-formed HCN and most likely through the extrusion of cyanogen which could not be detected or isolated. In addition, the plausible mechanisms were proposed for both transformations. The structures of the title compounds were identified by means of IR, 1H NMR, 13C NMR, 2D NMR spectra, TOF–MS and X-ray measurements.

scholarly journals Three New Biflavonoids from Chinese Dragon's Blood, Dracaena cochinchinensis

2012 ◽  
Vol 7 (5) ◽  
pp. 1934578X1200700 ◽  
Author(s):  
Jing Guan ◽  
Shun-Xing Guo
Keyword(s):  
Quantum Chemical Calculation ◽  
Quantum Chemical ◽  
Chemical Calculation ◽  
Dragon’S Blood ◽  
Esi Ms ◽  
H Nmr ◽  
Cd Spectrum ◽  
The Absolute ◽  
Circular Dichroïsm ◽  
C Nmr

Three new biflavonoids, named (2 Rγ S)-3′-methoxy-8-methylsocotrin-4′-ol (1), (2 Sγ R)-3′-methoxy-8-methylsocotrin-4′-ol (2), and (2 Rγ R)-8-methylsocotrin-4′-ol (3), were isolated from Chinese Dragon's blood [Dracaena cochinchinensis (Lour.) S. C. Chen], together with two known ones. The structures of these new biflavonoids were elucidated by a combination of HR-ESI-MS, 1H NMR, 13C NMR, HMQC, and HMBC spectra. The absolute configurations of compounds 1-4 were determined by quantum chemical calculation of the circular dichroism spectrum and comparison with the experimental CD spectrum.

Synthesis and Purification of L-Phenylalanine Oligo-Peptides Assisted by Phosphorus Oxychloride

2011 ◽  
Vol 365 ◽  
pp. 150-154
Author(s):  
Ming Xiu Lv ◽  
Li Ming Qiang ◽  
Kui Lu ◽  
Ying Yan Yao
Keyword(s):  
Self Assembly ◽  
Phosphorus Oxychloride ◽  
Inorganic Phosphorus ◽  
The Self ◽  
Reaction Products ◽  
Esi Ms ◽  
H Nmr ◽  
Rp Hplc ◽  
Proper Condition ◽  
C Nmr

Oligo-peptides have been focused on by chemists recently because of the strong bioactivity an activity as drug or precursor of drug. α-Amino acid could self-assemble into oligo-peptides with the assistance of inorganic phosphorus reagents, so it could provide a new method to synthesize peptides. In this paper, the self-assembly reaction of L-Phenylalanine mediated by phosphorus oxychloride were studied by using ESI-MS. The proper condition of self-assembly reaction of L-Phe was reported. The reaction products were purified by RP-HPLC and Phe-Phe dipeptide was characterized by the means of IR, 1H-NMR, 13C-NMR and ESI-MS/MS.

Anwendungen der 2 D-NMR-Spektroskopie in der Organophosphorchemie Beispiel: L-Menthyldichlorphosphan / Applications of the 2D NMR Spectroscopy in the Organophosphorus Chemistry Example: L-Menthyldichlorophosphine

1982 ◽  
Vol 37 (12) ◽  
pp. 1661-1664 ◽  
Author(s):  
Martin Feigel ◽  
Gerhard Hägele ◽  
Axel Hinke ◽  
Gudrun Tossing
Keyword(s):  
Nmr Spectroscopy ◽  
2D Nmr ◽  
2D Nmr Spectroscopy ◽  
H Nmr ◽  
Nmr Parameters ◽  
Nmr Data ◽  
Organophosphorus Chemistry ◽  
C Nmr

2D NMR ist used to determine the 1H NMR parameters of L-Menthyldichlorophosphine. 13C NMR data are given

scholarly journals Bioguided Fraction and Isolation of the Antitumor Components fromPhyllanthus niruriL.

2016 ◽  
Vol 2016 ◽  
pp. 1-7 ◽  
Author(s):  
Zhi-Zhong Zheng ◽  
Liang-Hua Chen ◽  
Shao-Song Liu ◽  
Yuan Deng ◽  
Guo-Hua Zheng ◽  
...  
Keyword(s):  
Antitumor Activity ◽  
Ethyl Acetate Fraction ◽  
2D Nmr ◽  
Phyllanthus Niruri ◽  
Lower Toxicity ◽  
H Nmr ◽  
Cytotoxicity Assays ◽  
Antitumor Potential ◽  
Maximum Content ◽  
C Nmr

Phyllanthus niruriL., a well-known medicinal plant, has been used as a folk antitumor remedy in the worldwide scale. However, the antitumor components inP. nirurihave not been reported. In order to verify the antitumor components ofP. niruriand the plants which have the high content of these components, we isolated the antitumor components with bioguided fraction and isolation, by different chromatographic methods from the ethyl acetate fraction ofP. niruri., and identified them as ethyl brevifolincarboxylate and corilagin by1H-NMR,13C-NMR, 2D-NMR, and mass spectrometric analyses. Cell cytotoxicity assays showed that corilagin has broad-spectrum antitumor activity, a better antitumor potential, and lower toxicity in normal cells. Besides, the coefficient of drug interaction (CDI) of 10 μM corilagin and 20 μM cDDP reached up to 0.77, which means corilagin can promote the antitumor activity of cDDP. Furthermore, by the extensive screening among 10 species of plants reported to contain corilagin, we found thatDimocarpus longanLour. has the maximum content of corilagin. In conclusion, corilagin is the major active antitumor composition inP. niruri.L. on HCC cells and has high content inD. longan.

scholarly journals Synthesis and spectroscopic properties of β-meso directly linked porphyrin–corrole hybrid compounds

2018 ◽  
Vol 14 ◽  
pp. 187-193 ◽  
Author(s):  
Baris Temelli ◽  
Hilal Kalkan
Keyword(s):  
Fluorescence Spectroscopy ◽  
Condensation Reaction ◽  
2D Nmr ◽  
Spectroscopic Properties ◽  
H Nmr ◽  
Hybrid Compounds ◽  
Absorption And Fluorescence Spectroscopy ◽  
First Time ◽  
C Nmr

The preparation of β-meso directly linked porphyrin–corrole hybrids was realized for the first time via an InCl3-catalyzed condensation reaction of 2-formyl-5,10,15,20-tetraphenylporphyrins with meso-substituted dipyrromethanes. Hybrid compounds have been characterized by 1H NMR, 13C NMR, 2D NMR, UV–vis absorption and fluorescence spectroscopy.

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