scholarly journals Ethnopharmacological, Phytochemical, Pharmacological and Toxicological Aspects of Bauhinia forficata: A Mini-Review Covering the Last Five Years

2018 ◽  
Vol 13 (7) ◽  
pp. 1934578X1801300 ◽  
Author(s):  
Camile Cecconi Cechinel-Zanchett ◽  
Sérgio Faloni de Andrade ◽  
Valdir Cechinel-Filho

This mini review focuses on the ethnopharmacology, phytochemical, and biological/pharmacological activity and toxicology of the medicinal plant, Bauhinia forficata reported during 2012–2016. The results confirmed the continuous use of this plant, especially the leaves, for medicinal purposes, particularly as remedies for the treatment of diabetes and other ailments. Other new biological potential was evidenced, including anti-ulcerogenic, hypocholesterolemic, hepatoprotective and diuretic effects. Clinical and toxicological studies have advanced gradually, requiring more detailed experiments, to ensure the safe use of this plant for medication. Some new flavonoids were detected in this species, but significant differences were observed when comparing the chemical composition of its sub-species.

2000 ◽  
Vol 55 (5-6) ◽  
pp. 478-480 ◽  
Author(s):  
Karina L. da Silva ◽  
Maique Weber Biavatti ◽  
Silvana Nair Leite ◽  
Rosendo A. Yunes ◽  
Franco Delle Monache ◽  
...  

We have isolated two phytoconstituents present in the B. forficata leaves, a medicinal plant employed in folk medicine specially for the treatment of diabetes. These compounds were isolated by column chromatography and identified as β-sitosterol and kaempferol-3,7-dirhamnoside (kaempferitrin) by spectroscopical data and comparison with authentic samples. A comparative study with different parts of the plant indicated that the latter is present only in the leaves, suggesting that it might be useful for a suitable quality control of phytotherapeutics which contain this organ of B. forficata in its composition.


Plants ◽  
2021 ◽  
Vol 10 (2) ◽  
pp. 230
Author(s):  
Oleh Koshovyi ◽  
Ain Raal ◽  
Igor Kireyev ◽  
Nadiya Tryshchuk ◽  
Tetiana Ilina ◽  
...  

The prospect of creating a new medicine with psychotropic activity is shown as a result of studying the chemical composition and pharmacological activity of modified dry extracts of motherwort (Leonurus cardiaca L.) tincture. The most promising substances were the dry extracts, modified by adding small amounts of arginine, valine, phenylalanine, glycine, lysine, and alanine. A total of 15 main phenolic substances were found in the extracts, and eight of them were identified. There were also 10 hydroxycinnamic acids in these extracts, three of which were identified (chlorogenic, caffeic, and rosmarinic acids). The dominant hydroxycinnamic acids were chlorogenic and caffeic acids. Among flavonoids, catechin, hyperoside, and rutin were identified. It should be noted that the extracts had a significant content of ellagic acid. On the basis of the results of the phytochemical analysis of the extracts, it can be concluded that the composition of phenolic compounds does not differ significantly, and the main differences are related to amino acids, which obviously have an impact on the overall pharmacological effect. The results obtained indicate the presence of anxiolytic activity in the motherwort extracts studied in complex with amino acids. The extracts with glycine, valine, and arginine were more effective in reducing anxiety in animals.


Author(s):  
P.L. Palatty ◽  
A.R. Shivashankara ◽  
M.S. Baliga ◽  
A. Jaiswal ◽  
P. Pankaj ◽  
...  

2020 ◽  
Vol 152 ◽  
pp. 104420 ◽  
Author(s):  
Svetlana Đogo Mračević ◽  
Marko Krstić ◽  
Aleksandar Lolić ◽  
Slavica Ražić

2008 ◽  
Vol 3 (4) ◽  
pp. 1934578X0800300
Author(s):  
Patrícia Walter Rosa ◽  
Marina Da Silva Machado ◽  
Rivaldo Niero ◽  
Susana Zacchino ◽  
Maria De Los Ángeles Gette ◽  
...  

Epidendrum mosenii is a Brazilian medicinal plant, traditionally used to treat infections and pains. This study reports on the chemical composition and microbiological properties of different parts and in different seasons of this plant. Results demonstrate that 4,3′,5′-trihydroxy-3-methoxy-dihydrostilbene (1), 4,5-dihydroxy-3,3-dimethoxy-dihydrostilbene (2) and pholidotin (3) were mainly present in the roots in all seasons, and the yield of mass extract increased their recovery in other parts, such as the stem and leaves for compounds (2) and (3), in summer and winter, respectively. The antifungal results indicate that compounds (1) and (2) have interesting activity against Cryptococcus neoformans, Microsporum gypseum, Trychophyton rubrum and Trychophyton mentagrophytes with MIC values between 62.5 and 125 μg/mL. Taken together, these results strongly suggest that the antifungal properties of E. mosenii are related, at least in part, to the presence of dihydrostilbenes 1 and 2, and this is useful for quality control of phytopreparations based on this plant, justifying the popular use of this plant to treat infections.


Plants ◽  
2019 ◽  
Vol 8 (7) ◽  
pp. 193
Author(s):  
Blanco-Salas ◽  
Vazquez ◽  
Hortigón-Vinagre ◽  
Ruiz-Tellez

Plants from the genus Mercurialis have a long history of use as herbal remedies in traditional Spanish medicine. The growing interest in the conservation of knowledge related to biodiversity has encouraged us to review the bioactive phytochemicals from the four most widespread Mercurialis species in the Iberian Peninsula (M. annua L., M. ambigua L., M. perennis L., and M. tomentosa L.). First, the medicinal uses of these four species throughout Spain were compiled, and then a bibliographical search on their chemical composition was conducted in an attempt to justify their reported traditional uses. We found that most of the medicinal uses of Mercurialis spp. are supported by scientific evidence. This includes its antidiabetic and antihypertensive properties attributable to the flavonoid rutin and narcissin, respectively; its benefits in the treatment of skin dark spots, attributable to mequinol; and its anti-inflammatory activity, attributable to scopoletin, kaempferol, squalene, and cycloartenol. This review contributes to the validation of the medicinal uses of Mercurialis spp. in Spain and provides some new avenues for further investigations on the biological activity of this interesting medicinal plant.


2016 ◽  
Vol 11 (7) ◽  
pp. 1934578X1601100
Author(s):  
Chun-Tao Che ◽  
Ming Zhao ◽  
Brian Guo ◽  
Michael M. Onakpa

This is a review on the pharmacological properties and chemical composition of Icacina trichantha (Icacinaceae), a food and medicinal plant native to West Africa. The tuber is a good source of nutrients such as starch; it also exhibits a variety of pharmacological activities in animal models. Chemical analysis has revealed the presence of a series of unusual pimarane-type diterpenes.


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