scholarly journals Icacina trichantha, A Tropical Medicinal Plant

2016 ◽  
Vol 11 (7) ◽  
pp. 1934578X1601100
Author(s):  
Chun-Tao Che ◽  
Ming Zhao ◽  
Brian Guo ◽  
Michael M. Onakpa
Keyword(s):  
Chemical Composition ◽  
Animal Models ◽  
Chemical Analysis ◽  
Medicinal Plant ◽  
West Africa ◽  
Pharmacological Properties ◽  
Good Source ◽  
Pharmacological Activities

This is a review on the pharmacological properties and chemical composition of Icacina trichantha (Icacinaceae), a food and medicinal plant native to West Africa. The tuber is a good source of nutrients such as starch; it also exhibits a variety of pharmacological activities in animal models. Chemical analysis has revealed the presence of a series of unusual pimarane-type diterpenes.

Pharmacological Importance of Chromolaena odorata: a review

2021 ◽  
pp. 8-11
Author(s):  
Angitha Ajay ◽  
Rupesh Kumar M ◽  
Shamal Badhusha PA ◽  
Abhishek K ◽  
Sanjay K Gowda ◽  
...  
Keyword(s):  
Medicinal Plant ◽  
West Africa ◽  
Pharmacological Properties ◽  
Conventional System ◽  
Chromolaena Odorata ◽  
Pharmacological Activities ◽  
Tropical Asia ◽  
Clinical Investigations ◽  
Medicinal Use ◽  
Medicinal Properties

Chromolaena odorata (Asteraceae) is commonly referred to as Siam Weed, a major medicinal plant found in tropical Asia, Australia, and West Africa. The medicinal use of Chromolaena odorata had been documented in the conventional system such as the Siddha, Unani, Ayurveda. The pharmacological properties of this plant are widely varying. A wide variety of attractive but limited compounds were extracted from this Chromolaena odorata and the pharmacological  activities   were   screened   out.   This   review   the   various   properties  of Chromolaena odorata and focus on its various medicinal properties. It is an attractive subject for further experimental and clinical investigations. This article will give an exhaustive summary and analysis of Chromolaena odorata pharmacological activities. The present article including the detailed exploration of pharmacological properties of C. odorata is an attempt to provide a direction for further research.

scholarly journals HING (Ferula foetida Regel): A potent Unani Herb with its descriptive parameters of pharmacognosy and pharmacology: A Review

2020 ◽  
Vol 10 (5) ◽  
pp. 362-367
Author(s):  
Rasikh Javaid ◽  
Ghazala Javed ◽  
Raheela Javaid ◽  
, Anju ◽  
Farah Ahmed ◽  
...  
Keyword(s):  
Medicinal Plant ◽  
Central Asia ◽  
Present Review ◽  
Pharmacological Properties ◽  
Pharmacological Activities ◽  
Unani Medicine ◽  
Traditional Uses ◽  
Pharmacological Studies ◽  
Botanical Description ◽  
Biological And Pharmacological Activities

Hing (Family- Umbelliferae) or asafoetida is the latex obtained from living rootstocks or taproots of several species of Ferula, e.g. F. alliacea Boiss, F. rubricaulis Boiss, F. assafoetida Linn and F. narthex Boiss found in central Asia. Asafoetida occurs in three forms, viz Tears, Mass and Paste. Hing has shown diverse biological and pharmacological activities. It has been used in Unani Medicine (Tibb-e-Unani) and other Traditional Systems of Medicine from time immemorial and it is described as diuretic, anti-diabetic, emmenagogue etc. The present review highlights the botanical description, traditional uses, pharmacognositcal features, pharmacological properties and pharmacological studies conducted on this Medicinal plant used in Unani system of medicine. Keywords: Hing; Ferula foetida; Unani Medicine; Traditional Uses; Pharmacological Properties

scholarly journals Sorrel (Rumex acetosa L.): Not Only a Weed but a Promising Vegetable and Medicinal Plant

2020 ◽  
Vol 86 (3-4) ◽  
pp. 234-246
Author(s):  
Helena Korpelainen ◽  
Maria Pietiläinen
Keyword(s):  
Medicinal Plant ◽  
Oxalic Acid ◽  
Bioactive Compounds ◽  
Rumex Acetosa ◽  
Good Source ◽  
Pharmacological Activities ◽  
Plant Parts ◽  
Cultivated Plant ◽  
Ancient Times ◽  
Folk Remedies

AbstractSorrel (Rumex acetosa L.) is a perennial, dioecious herb occupying a variety of habitats. Sorrel has been utilized as a wild gathered plant for thousands of years and as a cultivated plant for centuries. Primarily roots but also other tissues have been used in folk remedies since ancient times. In recent investigations, different phytochemical and pharmacological activities of Rumex have been analyzed, and many bioactive compounds have been detected. Sorrel is also a tasty plant and its leaves are a good source of macronutrients and micronutrients. However, the presence of high levels of oxalic acid reduces the bioavailability of some minerals, especially calcium, when using uncooked plant parts. Further investigations on different sorrel compounds are needed to show their true effect. It is beneficial that sorrel is easily propagated and there are no serious insect or disease problems. A few types of R. acetosa seeds are presently available commercially, including wild types and a few cultivars.

scholarly journals Pharmacological Properties of Polyphenols: Bioavailability, Mechanisms of Action, and Biological Effects in In Vitro Studies, Animal Models, and Humans

Biomedicines ◽  
2021 ◽  
Vol 9 (8) ◽  
pp. 1074
Author(s):  
Kristine Stromsnes ◽  
Rudite Lagzdina ◽  
Gloria Olaso-Gonzalez ◽  
Lucia Gimeno-Mallench ◽  
Juan Gambini
Keyword(s):  
Molecular Structure ◽  
Animal Models ◽  
Biological Effects ◽  
Mechanisms Of Action ◽  
Pharmacological Properties ◽  
Concomitant Treatment ◽  
State Of Health ◽  
Pharmacological Activities ◽  
Chemical Structures

Drugs are bioactive compounds originally discovered from chemical structures present in both the plant and animal kingdoms. These have the ability to interact with molecules found in our body, blocking them, activating them, or increasing or decreasing their levels. Their actions have allowed us to cure diseases and improve our state of health, which has led us to increase the longevity of our species. Among the molecules with pharmacological activity produced by plants are the polyphenols. These, due to their molecular structure, as drugs, also have the ability to interact with molecules in our body, presenting various pharmacological properties. In addition, these compounds are found in multiple foods in our diet. In this review, we focused on discussing the bioavailability of these compounds when we ingested them through diet and the specific mechanisms of action of polyphenols, focusing on studies carried out in vitro, in animals and in humans over the last five years. Knowing which foods have these pharmacological activities could allow us to prevent and aid as concomitant treatment against various pathologies.

scholarly journals Eriosema (Fabaceae) Species Represent a Rich Source of Flavonoids with Interesting Pharmacological Activities

2015 ◽  
Vol 10 (7) ◽  
pp. 1934578X1501000 ◽  
Author(s):  
Maurice Ducret Awouafack ◽  
Pierre Tane ◽  
Michael Spiteller ◽  
Jacobus Nicolaas Eloff
Keyword(s):  
Erectile Dysfunction ◽  
Chemical Composition ◽  
Secondary Metabolites ◽  
Total Synthesis ◽  
Biological Activities ◽  
Chemical Diversity ◽  
Pharmacological Properties ◽  
Pharmacological Activities ◽  
Natural Sources ◽  
Synthetic Derivatives

Many flavonoids have so far been isolated as main secondary metabolites in plant species of the genus Eriosema (Fabaceae), which contains approximately 160 species. A total of 52 flavonoids including isoflavones, dihydroflavonols, flavonols, flavanones, dihydrochalcones, isoflavanone and their pyrano or glucoside derivatives were isolated and characterized from the five species of this genus investigated to date. Total synthesis and semi-synthesis (acetylation, methylation, hydrogenation, and cyclization) of some isolated flavonoids were reported. Due to several significant pharmacological properties (antimicrobial, cytotoxicity, anti-mycobacterial, antioxidant, antiviral, erectile-dysfunction, vasodilatory and hypoglycemic) of the isolated flavonoids and derivatives, more scientists should be interested in investigating Eriosema species. The present review is the first to document all flavonoids that have been reported from the genus Eriosema to date together with their synthetic and semi-synthetic derivatives, and their pharmacological properties. Dihydrochalcones, which are precursors of other classes of flavonoids, are very rare in natural sources and their isolation from Eriosema species may explain the large number of flavonoids found in this genus. It appears that isoflavone could be a marker for species in this genus. The 83 flavonoids (1–83) documented include 52 isolates, 31 semi-synthetic and 3 totally synthetic derivatives. Data were obtained from Google scholar, Pubmed, Scifinder, Sciencedirect, and Scopus. With 52 different flavonoids isolated from only 5 of the approximately 160 species it shows the remarkable chemical diversity of this genus. This compilation of the biological activities and chemical composition may renew the interest of pharmacologists and phytochemists in this genus.

scholarly journals Actual Aspects of Medical Application of Black Nut – Juglans Nigra L. (Review)

2019 ◽  
Vol 8 (3) ◽  
pp. 21-28
Author(s):  
A. V. Korochinsky ◽  
Ja. V. Daironas ◽  
V. V. Vernikovsky ◽  
I. N. Zilfikarov ◽  
E. F. Stepanova ◽  
...  
Keyword(s):  
Chemical Composition ◽  
Medicinal Plant ◽  
Raw Materials ◽  
Black Walnut ◽  
Juglans Nigra ◽  
Biologically Active ◽  
Raw Material ◽  
Pharmacological Properties ◽  
Plant Raw Material ◽  
Made In

Introduction. Herbal drugs of black walnut (Juglans nigra L.) are not registered on the territory of the Russian Federation at the present time. However, the State Register of Medicinal Products includes an extract of unripe fruits of a related species walnut (Juglans regia L.) «Yuglanex» (made in Russia) and the complex herbal drug «Tonsilgon» (made in Germany). A number of biologically active food supplements from black walnut raw materials have been registered by Russian Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing. They are an additional source of phenolic compounds as tannins and flavonoids. The purpose of the article is to study and systematize up-to-date information on the chemical composition of the medicinal plant raw material of black walnut and the pharmacological properties of its main biologically active compounds.Text. All parts of the black walnut are used in the ethnomedicine of the indigenous population of North America according to indications similar to the walnut in Asia and the Manchurian nut in the Far East: snake bites, fever and disorders of the gastrointestinal tract.The chemical composition of the medicinal plant raw material of black walnut is dencently walnut by its qualitative composition. Fruits, bark and leaves of black walnut contain a rich polyphenol complex (naphthoquinones, in particular, juglon and its derivatives, tannins, flavonoids, phenolic acids), vitamins, essential oil, organic acids. However, the quantitative analysis revealed a higher content of biologically active substances in the raw black walnut, especially in relation to polyphenolic compounds.The scientific literature describes the results of experiments on animals, confirming antioxidant, antimicrobial, antifungal, antiviral, antiparasitic, hypoglycemic, antispasmodic, and anti-tumor effect on certain cell lines.Conclusion. As a result of studying the literature and systematizing the current information on the chemical composition of the medicinal plant raw material of the black nut and the pharmacological properties of its main biologically active compounds, it has been established that the main properties are related to the presence of the phenol complex. However, a deeper study of the chemical composition is required. Both the total extracts of the black walnut from plant raw materials and individual compounds show predominantly antimicrobial, antifungal, antioxidant, antiviral, hypotensive, immunomodulatory, antitumor and antispasmodic activities in preclinical trials.

The effect of different extraction methods on chemical composition profile and pharmacological activities of essential oils and hydrosols

Planta Medica ◽  
2016 ◽  
Vol 81 (S 01) ◽  
pp. S1-S381
Author(s):  
F Ghavidel ◽  
MM Zarshenas ◽  
A Sakhteman ◽  
A Gholami ◽  
Y Ghasemi ◽  
...  
Keyword(s):  
Chemical Composition ◽  
Essential Oils ◽  
Extraction Methods ◽  
Composition Profile ◽  
Pharmacological Activities

Tamarix articulata (T. articulata) - An Important Halophytic Medicinal Plant with Potential Pharmacological Properties

2019 ◽  
Vol 20 (4) ◽  
pp. 285-292 ◽  
Author(s):  
Abdullah M. Alnuqaydan ◽  
Bilal Rah
Keyword(s):  
Medicinal Plant ◽  
Biological Activities ◽  
Wide Spectrum ◽  
Biological Properties ◽  
In Vivo Model ◽  
Drug Candidate ◽  
Phytochemical Analysis ◽  
Pharmacological Properties

Background:Tamarix Articulata (T. articulata), commonly known as Tamarisk or Athal in Arabic region, belongs to the Tamaricaece species. It is an important halophytic medicinal plant and a good source of polyphenolic phytochemical(s). In traditional medicines, T. articulata extract is commonly used, either singly or in combination with other plant extracts against different ailments since ancient times.Methods:Electronic database survey via Pubmed, Google Scholar, Researchgate, Scopus and Science Direct were used to review the scientific inputs until October 2018, by searching appropriate keywords. Literature related to pharmacological activities of T. articulata, Tamarix species, phytochemical analysis of T. articulata, biological activities of T. articulata extracts. All of these terms were used to search the scientific literature associated with T. articulata; the dosage of extract, route of administration, extract type, and in-vitro and in-vivo model.Results:Numerous reports revealed that T. articulata contains a wide spectrum of phytochemical(s), which enables it to have a wide window of biological properties. Owing to the presence of high content of phytochemical compounds like polyphenolics and flavonoids, T. articulata is a potential source of antioxidant, anti-inflammatory and antiproliferative properties. In view of these pharmacological properties, T. articulata could be a potential drug candidate to treat various clinical conditions including cancer in the near future.Conclusion:In this review, the spectrum of phytochemical(s) has been summarized for their pharmacological properties and the mechanisms of action, and the possible potential therapeutic applications of this plant against various diseases discussed.

Exploring the Chemistry and Therapeutic Potential of Triazoles: A Comprehensive Literature Review

2019 ◽  
Vol 19 (16) ◽  
pp. 1298-1368 ◽  
Author(s):  
Ankit Jain ◽  
Poonam Piplani
Keyword(s):  
Oxidative Stress ◽  
Drug Discovery ◽  
Literature Review ◽  
Structural Modification ◽  
Therapeutic Potential ◽  
Pharmacological Properties ◽  
Pharmacological Activities ◽  
Triazole Derivatives ◽  
Comprehensive Literature Review ◽  
The Common

: Triazole is a valuable platform in medicinal chemistry, possessing assorted pharmacological properties, which could play a major role in the common mechanisms associated with various disorders like cancer, infections, inflammation, convulsions, oxidative stress and neurodegeneration. Structural modification of this scaffold could be helpful in the generation of new therapeutically useful agents. Although research endeavors are moving towards the growth of synthetic analogs of triazole, there is still a lot of scope to achieve drug discovery break-through in this area. Upcoming therapeutic prospective of this moiety has captured the attention of medicinal chemists to synthesize novel triazole derivatives. The authors amalgamated the chemistry, synthetic strategies and detailed pharmacological activities of the triazole nucleus in the present review. Information regarding the marketed triazole derivatives has also been incorporated. The objective of the review is to provide insights to designing and synthesizing novel triazole derivatives with advanced and unexplored pharmacological implications.

The chemical composition of leucoxene in Cainozoic bauxite from Boolarra, Victoria

1942 ◽  
Vol 26 (179) ◽  
pp. 273-274 ◽  
Author(s):  
A. B. Edwards
Keyword(s):  
Chemical Composition ◽  
Chemical Analysis ◽  
Olivine Basalt ◽  
Pure Sample ◽  
Residual Structure ◽  
Aluminium Titanate

During a petrological examination of samples of bauxite from Boolarra, in south Gippsland, Victoria, it was noted that some specimens of the bauxite, which is largely derived from Tertiary olivine-basalt, contained numerous grains of yellow-brown to amber-yellow leucoxene. The leucoxene is clearly pseudo-morphous after ilmenite, residual particles of ilmenite being enclosed in many of the leucoxene grains. Most of the leucoxene grains are opaque, but occasional grains are translucent to transparent, though isotropic. Some of them show parallel markings suggestive of cleavage, but probably a residual structure from the replaced ilmenite. In view of the highly aluminous nature of the enclosing rock, there seemed some possibility that this mineral might be the little-known aluminium titanate, xanthitane. It was thought, therefore, that if a pure sample of the mineral could be prepared, a chemical analysis would establish its identity.

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