scholarly journals Phytochemical and Psychotropic Research of Motherwort (Leonurus cardiaca L.) Modified Dry Extracts

Plants ◽  
2021 ◽  
Vol 10 (2) ◽  
pp. 230
Author(s):  
Oleh Koshovyi ◽  
Ain Raal ◽  
Igor Kireyev ◽  
Nadiya Tryshchuk ◽  
Tetiana Ilina ◽  
...  

The prospect of creating a new medicine with psychotropic activity is shown as a result of studying the chemical composition and pharmacological activity of modified dry extracts of motherwort (Leonurus cardiaca L.) tincture. The most promising substances were the dry extracts, modified by adding small amounts of arginine, valine, phenylalanine, glycine, lysine, and alanine. A total of 15 main phenolic substances were found in the extracts, and eight of them were identified. There were also 10 hydroxycinnamic acids in these extracts, three of which were identified (chlorogenic, caffeic, and rosmarinic acids). The dominant hydroxycinnamic acids were chlorogenic and caffeic acids. Among flavonoids, catechin, hyperoside, and rutin were identified. It should be noted that the extracts had a significant content of ellagic acid. On the basis of the results of the phytochemical analysis of the extracts, it can be concluded that the composition of phenolic compounds does not differ significantly, and the main differences are related to amino acids, which obviously have an impact on the overall pharmacological effect. The results obtained indicate the presence of anxiolytic activity in the motherwort extracts studied in complex with amino acids. The extracts with glycine, valine, and arginine were more effective in reducing anxiety in animals.

Author(s):  
O. H. Doroshenko ◽  
S. M. Marchyshyn

Chemical composition of diuretic collection was studied. The presence of phenolic substances namely flavonoids, hydroxycinnamic acids and coumarines was proved. By HPLC method rutin, hiperoside, isoquercetin, luteolin, apigenin, coumarin, umbelliferon, scopoletin, chlorogenic, rosmarinic and ferulic acids were identified and their content was set.


Author(s):  
Shweta R. Patil ◽  
Savita S. Satpute ◽  
Shitalkumar S. Patil

Couroupita guianensis Aubl is also called as “Cannon ball tree”. The tree has enormous medicinal values since most of the parts like leaves; flower, fruits and stem are used as medicine to cure various diseases. During the last few decades it has been observed that there are numerous reports on anti-inflammatory activity, antiulcer activity, anticancer activity, antioxidant activity, anthelminthic activity of this plant. It is enriched with a number of compounds such as oils, ketosteroids, glycosides, courouptine, indirubin, isatin and phenolic substances. Phytochemical analysis of the extract showed the presence of major classes of phytochemicals alkaloids, phenolic compounds such as flavonoids, tannins and saponins. Studies reveal that C. guianensis. Aubl. Is a source of medicinally active compounds and have various pharmacological effects.


2018 ◽  
Vol 19 (2) ◽  
Author(s):  
Magdalena Woźniak ◽  
Marta Babicka ◽  
Iwona Rissmann ◽  
Bogdan Kędzia ◽  
Izabela Ratajczak

Introduction. Propolis is one of bee products, which is increasingly widespread in medicine. An important aspect regarding propolis is research on the analysis of its chemical composition. Propolis extracts have been found to include phenolic compounds (flavonoids as well as phenolic acids and their esters), terpenes, amino acids, vitamins and elements. The elements analyzed in the propolis extracts include both macro- and microelements, such as: calcium, magnesium, iron or selenium. Aim. The aim of the study was to determine concentration of selected elements in commercial available ethanolic extracts of propolis. Material and methods. In three ethanolic extracts of propolis were determined concentration of 14 elements (Ca, Mg, K, Na, Zn, Si, Pb, Co, Cr, Cu, Fe, Mn, Cd and Ni) using flame atomic absorption spectrometry. Results. In all propolis extracts the highest concentration among analyzed elements was determined for sodium, and in the lowest level of concentration was analyzed for copper and manganese. The concentrations of analyzed elements in extracts differed slightly and the highest differences were observed for magnesium, potassium and copper. In all examined samples the concentration of heavy metals was under detection limit of used analytical method. Conclusions. The results of the research presented in the paper indicate that the ethanolic extracts of propolis, despite slightly differences in the concentrations of the analyzed elements, can be a rich source of macro- and microelements.


Forests ◽  
2019 ◽  
Vol 10 (7) ◽  
pp. 553
Author(s):  
Qiufang Zhang ◽  
Zhijie Yang ◽  
Tingting Chen ◽  
Xiaoying Gong ◽  
Decheng Xiong ◽  
...  

Research Highlights: Warming alters the chemical composition of Cunninghamia lanceolata (Lamb.) Hook, resulting in increased production of macromolecular compounds that protect against heat stress. Background and Objectives: Low latitude forests are experiencing obvious climatic warming; however, the plant physiological responses to warming are not well understood. As warming induces moisture stress, we hypothesized that warming activates metabolites (i.e., lipids, phenolic compounds, amino acids) and causes damage to the leaves, exemplified by the increased concentrations of reactive oxygen species. Materials and Methods: We conducted a warming experiment in a C. lanceolata plantation. Plant physiological traits associated with nutrient status, reactive oxygen species, antioxidant enzymes species, and metabolites were measured. Results: Warming altered the chemical composition of C. lanceolata as it increased C:N ratios of leaves and roots. In particular, the concentrations of N and P in leaves and roots were significantly decreased under the warming condition, which might be related to the biomass production, namely, a dilution effect. Under the warming condition, most of the phospholipid compounds and proteins significantly increased. Leaf C, carbohydrates, amino acids, organic acids, flavonoids, and phenolic compounds were identified to have significantly lower concentrations under the warming treatment than those under the control treatment. These results suggested that moisture stress under the warming treatment may drive C deficiency and metabolic restriction in plants. Conclusions: Under the warming condition, C. lanceolata changed its energy utilization strategy and invested more resources to produce macromolecular compounds for protecting against heat stress. Warming in sub-tropical forests alters plant chemical properties, and thus may have an important consequence for nutrient cycling and soil C sequestration.


Author(s):  
Dr. Sukha ram ◽  
Dr. Amit Choudhary ◽  
Prof. Mita Kotecha ◽  
Dr. Krutika Chaudhary ◽  
Dr. Sunita Dudi

Atibala (Abutilon indicum Linn.) Sweet belonging to Family Malvaceae is very important plant since long in traditional medicine of India and grows in waste places. The drug is attributed Balya Kantivardhaka, Grahi, Ojovardhaka, Brinhana, Krimighna, Dahahara, Vatahara, Rasayana, Mutrajanana, Mridurechana, Vajikara, Kasahara and Vedanahara properties in different Ayurvedic classical texts. Pharmacognostical and phytochemical studies are essential for proper identification and authentication of the drug. Various methods including microscopy, physiochemical contents and phytochemical estimation along with quantitative analysis were conducted to evaluate Pharmacognostical, physiochemical and preliminary phytochemical standards of Atibala (Abutilon indicum (Linn.) Sweet roots. These studies can be helpful to define diagnostic features for identification and standardization of both intact and powdered drug. The organoleptic examination of the intact and powdered materials of roots of Atibala revealed light brown color, odourless odour and astringent and bitter taste. After analysing result of present study, we found presence of carbohydrates, tannins, protein, alkaloid, saponin, amino acids and phenolic compounds in both alcoholic and aqueous extract. Present study will be helpful in ensuring efficacy of the drug, safety, purity and about adulteration of drug.


2019 ◽  
Vol 38 (2) ◽  
pp. 149
Author(s):  
Jasmina Petreska Stanoeva ◽  
Nina Peneva ◽  
Marina Stefova ◽  
Viktor Gjamovski

Punica granatum L. is one of the species enjoying growing interest due to its complex and unique chemical composition that encompasses the presence of anthocyanins, ellagic acid and ellagitannins, gallic acid and gallotannins, proanthocyanidins, flavanols and lignans. This combination is deemed responsible for a wide range of health-promoting biological activities.This study was focused on the analysis of flavonoids, anthocyanins and phenolic acids in eight pomegranate varieties (Punica granatum) from Macedonia, in two consecutive years. Fruits from each cultivar were washed and manually peeled, and the juice was filtered. NaF (8.5 mg) was added to 100 ml juice as a stabilizer. The samples were centrifuged for 15 min at 3000 rpm and analyzed using an HPLC/DAD/MSn method that was optimized for determination of their polyphenolic fingerprints.The dominant anthocyanin in all pomegranate varieties was cyanidin-3-glucoside followed by cyanidin and delphinidin 3,5-diglucoside. From the results, it can be concluded that the content of anthocyanins was higher in 2016 compared to 2017. But in contrast, the total content of non-colored polyphenols was around 10 times lower in 2016 compared to the amount found in the same samples in 2017.


2021 ◽  
pp. 29-57
Author(s):  
Natalia Eduardovna Kolomiets ◽  
Roman Sergeevich Boev ◽  
Lyudmila Vladimirovna Zhalnina ◽  
Valeria Andreevna Tikhomirova ◽  
Denis Radikovich Kashapov ◽  
...  

The review summarizes information from the literature on the distribution, study of the composition and biological activity of metabolites, total extracts of plants of the genus Arctium L. of the world flora. In Russia, the roots of three species are allowed to be harvested and used: A. lappa, A. tomentosum, A. minus. To date, the most studied composition of metabolites and pharmacological properties of great burdock. The chemical composition of A. atlanticum, A. debrayi, A. leiobardanum, A. neumani, A. platylepis, A. pseudarctium, A. sardaimionense, A. scanicum, A. nemorosum and A. palladini has not been studied. About 360 substances related to polysaccharides, sesquiterpenes, triterpenes, fatty acids, phenolcarbonic acids, tannins, vitamins, lignans, sterols, polyacetylenes, amino acids, alkaloids, flavonoids, macro-and microelements and other were isolated and identified from the studied species. There are only a few publications about pharmacological activity of Arctium nemorosum, A. palladini, A. tomentosum and A. minus, and there is no information for other types. Total extracts and individual compounds of the studied burdock species in the experiment have a wide range of pharmacological activity. The information provided in the review shows that plants of the genus Arctium L., are promising for creating effective medicines. In addition, the fragmentation and lack of information on the composition of metabolites, pharmacological activity of most species of the genus burdock opens up great opportunities for researchers.


2010 ◽  
Vol 2 (2) ◽  
pp. 344-350 ◽  
Author(s):  
Puja Ohri ◽  
Satinder Kaur Pannu

The term, phenolics has been used to describe a group of structurally diverse plant secondary metabolites. This group includes metabolites derived from the condensation of acetate units (terpenoids), those produced by the modification of aromatic amino acids (phenylpropanoids, cinnamic acid, lignin precursor, catechols and coumarins), flavonoids, isoflavonoids, and tannins. The occurrence and metabolism of phenolic substances in plants, in response to injury or invasion by pathogens, such as fungi, bacteria and viruses have already been studied. Oxidised compounds produced in plants after invasion by pathogens often show considerable biological activity and are a common mechanism of resistance to plant pathogens. The present review gives information regarding the effects of different phenolic compounds on nematode system. It is found that these compounds are involved in plant defense and hence provide resistance against nematode attack.


2018 ◽  
Vol 69 (8) ◽  
pp. 1976-1979
Author(s):  
Ioana Asofiei ◽  
Ioan Calinescu ◽  
Adina Ionuta Gavrila ◽  
Daniel Ighigeanu ◽  
Diana Martin

It was designed and built a laboratory experimental installation (LEI) for the microwave pretreatment of vegetable materials. To study the influence of microwave pretreatment on the total phenolic content (TPC), a conventional extraction of polyphenols from treated and untreated fresh sea buckthorn leaves was performed. For short extraction times, the amount of phenolic compounds was higher for the extracts obtained from treated leaves, but a long pretreatment time (28 s) led to a decrease in TPC. The qualitative analysis showed that the chemical composition is not affected by the microwave pretreatment.


Molecules ◽  
2019 ◽  
Vol 25 (1) ◽  
pp. 70 ◽  
Author(s):  
Natália Conceição ◽  
Bianca R. Albuquerque ◽  
Carla Pereira ◽  
Rúbia C. G. Corrêa ◽  
Camila B. Lopes ◽  
...  

Camu-camu (Myrciaria dubia (Kunth) McVaugh) is a fruit economically relevant to the Amazon region, mostly consumed in the form of processed pulp. Our aim was to perform an unprecedented comparative study on the chemical composition and bioactivities of the camu-camu pulp and industrial bio-residues (peel and seed), and then the most promising fruit part was further explored as a functionalized ingredient in yogurt. A total of twenty-three phenolic compounds were identified, with myricetin-O-pentoside and cyanindin-3-O-glucoside being the main compounds in peels, followed by p-coumaroyl hexoside in the pulp, and ellagic acid in the seeds. The peel displayed the richest phenolic profile among samples, as well as the most significant antibacterial (MICs = 0.625–10 mg/mL) and anti-proliferative (GI50 = 180 µg/mL against HeLa cells) activities. For this reason, it was selected to be introduced in a food system (yogurt). Taken together, our results suggest the possibility of using the camu-camu peel as a source of food additives.


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