scholarly journals Bioactive Phytochemicals from Mercurialis spp. Used in Traditional Spanish Medicine

Plants ◽  
2019 ◽  
Vol 8 (7) ◽  
pp. 193
Author(s):  
Blanco-Salas ◽  
Vazquez ◽  
Hortigón-Vinagre ◽  
Ruiz-Tellez
Keyword(s):  
Biological Activity ◽  
Chemical Composition ◽  
Medicinal Plant ◽  
Scientific Evidence ◽  
Herbal Remedies ◽  
Medicinal Uses ◽  
History Of ◽  
Bioactive Phytochemicals ◽  
History Of Use ◽  
Antihypertensive Properties

Plants from the genus Mercurialis have a long history of use as herbal remedies in traditional Spanish medicine. The growing interest in the conservation of knowledge related to biodiversity has encouraged us to review the bioactive phytochemicals from the four most widespread Mercurialis species in the Iberian Peninsula (M. annua L., M. ambigua L., M. perennis L., and M. tomentosa L.). First, the medicinal uses of these four species throughout Spain were compiled, and then a bibliographical search on their chemical composition was conducted in an attempt to justify their reported traditional uses. We found that most of the medicinal uses of Mercurialis spp. are supported by scientific evidence. This includes its antidiabetic and antihypertensive properties attributable to the flavonoid rutin and narcissin, respectively; its benefits in the treatment of skin dark spots, attributable to mequinol; and its anti-inflammatory activity, attributable to scopoletin, kaempferol, squalene, and cycloartenol. This review contributes to the validation of the medicinal uses of Mercurialis spp. in Spain and provides some new avenues for further investigations on the biological activity of this interesting medicinal plant.

scholarly journals Ethnobotanical Research and Compilation of the Medicinal Uses in Spain and the Active Principles of Chiliadenus glutinosus (L.) Fourr. for the Scientific Validation of Its Therapeutic Properties

Plants ◽  
2021 ◽  
Vol 10 (3) ◽  
pp. 584
Author(s):  
Nadia Las Heras Las Heras Etayo ◽  
Félix Llamas ◽  
Carmen Acedo
Keyword(s):  
Scientific Evidence ◽  
Medicinal Species ◽  
Medicinal Uses ◽  
Organic Systems ◽  
Therapeutic Uses ◽  
Therapeutic Properties ◽  
Botanical Diversity ◽  
Bioactive Phytochemicals ◽  
Effective Drugs ◽  
Scientific Validation

The species Chiliadenus glutinosus (L.) Fourr. has a large number of therapeutic uses reported in the traditional Spanish medicine. The growing interest in preserving the ethnopharmacological knowledge related to the botanical diversity existing in Spain and the interest in achieving scientific validation of the therapeutic properties of medicinal species has led to the development of this study. To do it, all the known medicinal uses of Ch. glutinosus in Spain were compiled, then an exhaustive bibliographic research on its chemical composition was carried out, and finally, an in silico validation of the bioactive phytochemicals present in a higher proportion in the essential oil of Ch. glutinosus: camphor, borneol, lucinone, glutinone, quercetin, kutdtriol, and kaempferol; in an attempt to justify the reported traditional uses of the species. It was found that much of the traditional medicinal uses of Ch. glutinosus, along with the biological activity of its phytochemicals, are supported by scientific evidence. The results place this species in a prominent position to initiate possible lines of research to develop new, more effective drugs and improve therapies to treat conditions and diseases that affect the different organic systems of the human being.

scholarly journals Achillea Species as Sources of Active Phytochemicals for Dermatological and Cosmetic Applications

2021 ◽  
Vol 2021 ◽  
pp. 1-14
Author(s):  
Marcelina Strzępek-Gomółka ◽  
Katarzyna Gaweł-Bęben ◽  
Wirginia Kukula-Koch
Keyword(s):  
Scientific Evidence ◽  
Antimicrobial Properties ◽  
Environmental Stressors ◽  
World Health ◽  
Cosmetic Products ◽  
Cosmetic Ingredients ◽  
The World ◽  
History Of ◽  
History Of Use ◽  
Wound Healing Activity

Achillea spp. is well known for its broad range of applications and long history of use in traditional medicine around the world. Health benefits of Achillea extracts result from the multitude of secondary metabolites identified in the plants from this genus that include flavonoids, phenolic acids, terpenes, guaianolides, phytosterols, fatty acids, and organic acids. The properties of several Achillea extracts meet also the expectations of a vividly developing cosmetic market. An increasing number of studies on the dermatological properties of Achillea spp. are observed in the recent years, with Achillea millefolium L. being the most studied and used representative of the genus. There is strong scientific evidence showing that also other yarrow species might be rich sources of effective cosmetic ingredients, with skin calming and rejuvenating properties, wound healing activity, and anti-inflammatory potential. Several Achillea extracts and isolated compounds were also shown to display significant tyrosinase inhibitory, antioxidant, and antimicrobial properties and thus are interesting candidates for active ingredients of medications and cosmetic products protecting the skin from the harmful impact of environmental stressors. The aim of this review is to collect the current information on the composition and cosmeceutical significance of different Achillea species.

scholarly journals Traditional Chinese Medicine for Senile Dementia

2012 ◽  
Vol 2012 ◽  
pp. 1-13 ◽  
Author(s):  
Zhihong Lin ◽  
Jie Gu ◽  
Jin Xiu ◽  
Tingyan Mi ◽  
Jie Dong ◽  
...  
Keyword(s):  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Senile Dementia ◽  
Scientific Evidence ◽  
Sinapic Acid ◽  
Frequency Of Use ◽  
History Of ◽  
History Of Use

Traditional Chinese Medicine (TCM) has a 3000 years' history of human use. A literature survey addressing traditional evidence from human studies was done, with key result that top 10 TCM herb ingredients includingPoria cocos,Radix polygalae,Radix glycyrrhizae,Radix angelica sinensis, andRadix rehmanniaewere prioritized for highest potential benefit to dementia intervention, related to the highest frequency of use in 236 formulae collected from 29 ancient Pharmacopoeias, ancient formula books, or historical archives on ancient renowned TCM doctors, over the past 10 centuries. Based on the history of use, there was strong clinical support thatRadix polygalaeis memory improving. Pharmacological investigation also indicated that all the five ingredients mentioned above can elicit memory-improving effectsin vivoandin vitrovia multiple mechanisms of action, covering estrogen-like, cholinergic, antioxidant, anti-inflammatory, antiapoptotic, neurogenetic, and anti-Aβ activities. Furthermore, 11 active principles were identified, including sinapic acid, tenuifolin, isoliquiritigenin, liquiritigenin, glabridin, ferulic acid, Z-ligustilide, N-methyl-beta-carboline-3-carboxamide, coniferyl ferulate and 11-angeloylsenkyunolide F, and catalpol. It can be concluded that TCM has a potential for complementary and alternative role in treating senile dementia. The scientific evidence is being continuously mined to back up the traditional medical wisdom.

scholarly journals Shiitake Mushroom: A Tool of Medicine

2013 ◽  
Vol 5 (1) ◽  
pp. 24-32 ◽  
Author(s):  
Taufiqur Rahman ◽  
MBK Choudhury
Keyword(s):  
Blood Cholesterol ◽  
Gastric Ulcers ◽  
Shiitake Mushroom ◽  
Medicinal Mushrooms ◽  
Medicinal Uses ◽  
Nutritional Values ◽  
Patients With Diabetes ◽  
History Of ◽  
History Of Use

Medicinal mushrooms have an established history of use in traditional oriental therapies. Contemporary research has validated and documented much of the ancient knowledge. Over the last three decades, the interdisciplinary fields of science that study medicinal mushrooms has sprung up and has increasingly demonstrated the potent and unique properties of compounds extracted from a range of species. Currently, the field is being developed into a very fruitful area. Modern clinical practice in Japan, China, Korea and other Asian countries rely on mushroom-derived preparations.Mushrooms have been studied for nutritional and medical purposes for its various potential anti-tumoral and immunomodulatory componests like polysaccharides that have been identified. For medical purposes, mushrooms have been consumed to prevent cancer and cardiac diseases, to improve blood circulation and to reduce blood cholesterol level. Some of these mushrooms have also been used for the treatment of physical and emotional stress, osteoporosis, gastric ulcers and chronic hepatitis, for the improvement of the quality of life of patients with diabetes and especially for the stimulation of immunity.Shiitake has a history of medicinal uses. The mushroom is used as anticarcinogenic, antiinflammatory, antioxidant, antifungal, antibacterial, antiviral as well as antithrombotic in cardiovascular disorders. This article has been written to throw some light on Shiitake mushroom which has many nutritional values. Many Shiitake preparations came in market containing the active ingredients which can replace many other marketed synthetic medicines and may prove to have promising results with fewer side effects. DOI: http://dx.doi.org/10.3329/bjmb.v5i1.13428 Bangladesh J Med Biochem 2012; 5(1): 24-32

scholarly journals Chemical Composition and Antibacterial Activity of Extracts of Helleborus bocconei Ten. subsp. intermedius

2007 ◽  
Vol 2 (6) ◽  
pp. 1934578X0700200
Author(s):  
Sergio Rossellia ◽  
Antonella Maggio ◽  
Carmen Formisano ◽  
Francesco Napolitano ◽  
Felice Senatore ◽  
...  
Keyword(s):  
Antibacterial Activity ◽  
Biological Activity ◽  
Chemical Composition ◽  
Medicinal Plant ◽  
Respiratory Diseases ◽  
Light Petroleum ◽  
Aerial Parts

Helleborus bocconei Ten. subsp. intermedius (Ranunculaceae) is a Sicilian medicinal plant used for the treatment of pneumonia affecting cows and horses and for the removal of human decayed molars. The goal of our study was to assess the biological activity of Helleborus bocconei subsp. intermedius by testing its extracts for their activity against bacteria known to cause respiratory diseases. The two more active extracts (light petroleum from roots and aerial parts), as well as the dichloromethane extracts, were analyzed by GC/MS and their composition is reported.

Skuteczność i bezpieczeństwo stosowania korzenia Symphytum officinale L. – przegląd danych literaturowych

2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Katarzyna Kimel ◽  
Mirosława Krauze-Baranowska
Keyword(s):  
Clinical Trials ◽  
Chemical Composition ◽  
Raw Materials ◽  
Biologically Active ◽  
Herbal Products ◽  
Plant Raw Materials ◽  
Beneficial Effects ◽  
History Of ◽  
Ancient Times ◽  
History Of Use

Comfrey root – Symphyti radix has been present in medicine since ancient times. Nowadays, European Medicine Agency (EMA) restricts its only for external use, in short therapies not exceeding 10 days. The last decade has been characterized by the progress in research on the chemical composition and metabolism of biologically active compounds present in the root and leaves. The result is the presence of herbal medicinal products containing comfrey root extracts with reduced content or free of toxic pyrrolizidine alkaloids on the European market of herbal products. Moreover, the medicinal properties of leaves from another Symphytum species, namely Russian comfrey, are also in the use. The results of clinical trials indicate the beneficial effects of plant raw materials obtained from comfreys in musculoskeletal system disorders – comfrey root and skin inflammations – leaves of Russian comfrey. The paper presents the history of use, chemical composition, therapeutic effect and toxicity of comfrey, as well as characterizes clinical trials on products containing comfrey extracts from root and leaves.

scholarly journals A Graded Approach for Evaluating Health Claims about Plant-Based Food Supplements: Application of a Case Study Methodology

Nutrients ◽  
2021 ◽  
Vol 13 (8) ◽  
pp. 2684
Author(s):  
Hélène Chevallier ◽  
Florent Herpin ◽  
Hélène Kergosien ◽  
Gabrielle Ventura ◽  
François-André Allaert
Keyword(s):  
Scientific Evidence ◽  
Red Clover ◽  
Blood Lipid ◽  
Food Supplements ◽  
Health Claims ◽  
Case Study Methodology ◽  
History Of ◽  
Study Methodology ◽  
History Of Use

The implementation of REGULATION (EC) No 1924/2006 has led to the formation of a list of health claims that can be used in food supplements (EU 432/2012). However, such supplements are often composed of plant preparations with claims omitted from this list. The peculiarity of plants is related to their long history of use, that could allow claims based on traditionally recognized health effects. In addition, the scientific literature has been enriched over the years through clinical studies that have assessed the bioavailability and efficacy of bioactive components, and investigated their mechanisms of action. Based on existing recognized models which aim to classify research according to the level of scientific evidence, Synadiet developed a three-grade model (A, B or C) for assessing plants health claims. In this paper, the applicability of the model is illustrated through an example for which a Grade B health claim attesting the possible contribution of red clover isoflavones to the improvement of blood lipid levels in postmenopausal women has been attributed. The model appears able to be easily extrapolated to claims pertaining to other plants. If adopted by consensus at European level, this model could initiate the implementation of a positive list of health claims on plant preparations.

Anethumgraveolens: Physicochemical Properties, Medicinal Uses, Antimicrobial Effects, Antioxidant Effect, Anti-Inflammatory and Analgesic Effects: A Review

2017 ◽  
Vol 8 (03) ◽  
Author(s):  
Huda Jasim Altameme ◽  
Imad Hadi Hameed ◽  
Lena Fadhil Hamza
Keyword(s):  
Antimicrobial Activity ◽  
Moderate Activity ◽  
Medicinal Uses ◽  
Analgesic Effects ◽  
Wide Range ◽  
The Family ◽  
History Of ◽  
Annual Herb ◽  
History Of Use ◽  
Acetone Extracts

Anethumgraveolens, belong to the family Umbelliferae, is indigenous to southern Europe. It is an annual herb growing in the Mediterranean region, central and southern Asia.Now it is cultivated widely throughout the world. It is used traditionally as a popular aromatic herb and spice that has a very long history of use going back to more than 5,000 years. It was used as a remedy for indigestion and flatulence and as milk secretion stimulant. The essential oil and different extracts of Anethumgraveolensseeds exerted antimicrobial activity against wide range of microorganisms. The essential oils and acetone extracts shown antimicrobial activity against Staphylococcus aureus, Bacillus cereus, Enterococcus faecalis, Listeria monocytogenes, Escherichia coli, Yersinia enterocolitica, Salmonella choleraesuis, S. typhimurium, Shigellaflexneri, Salmonella typhii, Pseudomonas aeruginosa, and Mycobacterium. Anethumgraveolens seed extracts exerted moderate activity against Helicobacter pylori.

scholarly journals Cichorium intybus: Traditional Uses, Phytochemistry, Pharmacology, and Toxicology

2013 ◽  
Vol 2013 ◽  
pp. 1-13 ◽  
Author(s):  
Renée A. Street ◽  
Jasmeen Sidana ◽  
Gerhard Prinsloo
Keyword(s):  
Cichorium Intybus ◽  
Medicinal Uses ◽  
Traditional Uses ◽  
Toxicological Data ◽  
Coffee Substitute ◽  
History Of ◽  
Pharmacology And Toxicology ◽  
Pharmacological Potential ◽  
History Of Use ◽  
Scientific Validation

The genusCichorium(Asteraceae) is made up of six species with major geographical presence in Europe and Asia.Cichorium intybus, commonly known as chicory, is well known as a coffee substitute but is also widely used medicinally to treat various ailments ranging from wounds to diabetes. Although this plant has a rich history of use in folklore, many of its constituents have not been explored for their pharmacological potential. Toxicological data onC. intybusis currently limited. This review focuses on the economic and culturally important medicinal uses ofC. intybus. Traditional uses, scientific validation, and phytochemical composition are discussed in detail.

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