scholarly journals Assessment of oxygen-uptake efficiency slope in healthy children and children with heart disease: Generation of appropriate reference values for the OUES variable

2018 ◽  
Vol 26 (2) ◽  
pp. 177-184 ◽  
Author(s):  
Carlos AC Hossri ◽  
Isabela PM Alves de Souza ◽  
Joana ST de Oliveira ◽  
Luiz E Mastrocola
Keyword(s):  
Heart Disease ◽  
Oxygen Uptake ◽  
Children And Adolescents ◽  
Surface Area ◽  
Reference Values ◽  
Functional Capacity ◽  
Body Surface ◽  
Congenital Heart ◽  
Reference Value ◽  
Oxygen Uptake Efficiency Slope

Background Oxygen-uptake efficiency slope (OUES) is an objective measure of functional capacity that does not require a maximal effort but is considerably dependent on anthropometric variables and requires the generation of an appropriate reference value in children. This study aimed to establish normal reference values for OUES/kg in children with and without congenital heart diseases. Besides that, reference values are presented secondarily for OUES per body surface area (OUES/BSA). Design Cross-sectional. Methods Six hundred and seventy-six children and adolescents performed a maximal cardiopulmonary exercise test (305 healthy controls and 371 individuals with congenital heart defect), between four and 21 years old (481 males and 195 females, with a mean age of 12 years). Results The OUES reference value for the classification of children and adolescents with normal functional capacity (>80% of predicted maximum oxygen uptake) was 34.63 (sensitivity 77% and specificity 83%, p < 0.05). Regarding the body surface area, considering healthy patients and those with heart disease, the cutoff value of the OUES/BSA was 1151 with sensitivity of 79% and specificity of 79%. Conclusions OUES/kg may be an important marker tool in the differentiation between preserved or abnormal functional capacity in children and adolescents with and without congenital heart disease, even at the submaximal level of exercise.

Accuracy of oxygen uptake efficiency slope in adults with congenital heart disease

2009 ◽  
Vol 133 (1) ◽  
pp. 74-79 ◽  
Author(s):  
Alessandro Giardini ◽  
Salvatore Specchia ◽  
Gaetano Gargiulo ◽  
Diego Sangiorgi ◽  
Fernando M. Picchio
Keyword(s):  
Congenital Heart Disease ◽  
Heart Disease ◽  
Oxygen Uptake ◽  
Congenital Heart ◽  
Uptake Efficiency ◽  
Oxygen Uptake Efficiency Slope

Maximal versus sub-maximal effort during cardiopulmonary exercise testing in adults with congenital heart disease: outcome analysis of short-term cardiac-related events

2020 ◽  
pp. 1-6
Author(s):  
Bibhuti B. Das ◽  
Aliana Godoy ◽  
Talya Kadish ◽  
Jianli Niu
Keyword(s):  
Congenital Heart Disease ◽  
Oxygen Consumption ◽  
Heart Disease ◽  
Oxygen Uptake ◽  
Congenital Heart ◽  
Respiratory Exchange Ratio ◽  
Adult Congenital Heart Disease ◽  
Short Term ◽  
Adult Congenital ◽  
Oxygen Uptake Efficiency Slope

Abstract Peak respiratory exchange ratio is an objective marker of patient effort during cardiopulmonary exercise testing. We evaluated exercise variables in 175 adult congenital heart disease patients and the impact of respiratory exchange ratio on the prognostic value of exercise variables for short-term cardiac-related events. Of 175 patients, 110 completed the exercise test with a peak respiratory exchange ratio of ≥1.10 and the remaining 65 had a peak respiratory exchange ratio of <1.10. Peak oxygen consumption, the percentage of oxygen consumption at the ventilatory threshold, peak heart rate, percentage predicted peak heart rate, double product, oxygen uptake efficiency slope, and the number of patients with exercise oscillatory ventilation were reduced significantly in patients with a respiratory exchange ratio of <1.10 compared to those with a respiratory exchange ratio of ≥1.10. After a median follow-up of 21 months, total cardiac-related events occurred in 37 (21%) patients. Multivariate Cox proportional hazard analysis showed that the percentage predicted peak oxygen consumption, and oxygen uptake efficiency slope were independent predictors of cardiac-related events only in patients with a peak respiratory exchange ratio of ≥1.10. Sub-maximal exercise performance can be preserved in adult congenital heart disease patients. The percentage predicted oxygen consumption and the oxygen uptake efficiency slope are two independent predictors for short-term cardiac-related events in adult congenital heart disease patients.

scholarly journals Oxygen uptake efficiency slope in children with congenital heart disease versus healthy children

2019 ◽  
Vol 11 (4) ◽  
pp. e383-e384
Author(s):  
Arthur Gavotto ◽  
D’arcy Vandenberghe ◽  
Hamouda Abassi ◽  
Helena Bertet ◽  
Valerie Macioce ◽  
...  
Keyword(s):  
Congenital Heart Disease ◽  
Heart Disease ◽  
Oxygen Uptake ◽  
Congenital Heart ◽  
Healthy Children ◽  
Uptake Efficiency ◽  
Oxygen Uptake Efficiency Slope

scholarly journals FUNCTIONAL CAPACITY IN CHILDREN AND ADOLESCENTS WITH CONGENITAL HEART DISEASE

2019 ◽  
Vol 37 (1) ◽  
pp. 65-72
Author(s):  
Camila Wohlgemuth Schaan ◽  
Gabriela Feltez ◽  
Beatriz D’Agord Schaan ◽  
Lucia Campos Pellanda
Keyword(s):  
Physical Activity ◽  
Congenital Heart Disease ◽  
Heart Disease ◽  
Children And Adolescents ◽  
Functional Capacity ◽  
Congenital Heart ◽  
Heart Defects ◽  
Activity Level ◽  
Short Version ◽  
Blood Collection

ABSTRACT Objective: To evaluate the physical activity level and functional capacity of children and adolescents with congenital heart disease and to describe correlations between functionality, surgical and echocardiographic findings, metabolic and inflammatory profile and differences between acyanotic and cyanotic heart defects. Methods: A cross-sectional study including children and adolescents with congenital heart disease between six and 18 years old that were evaluated with the 6-minute walk test (6MWT) to assess functional capacity. The short version form of the International Physical Activity Questionnaire (IPAQ) was performed to evaluate physical activity levels. Also, echocardiography and blood collection, to evaluate the metabolic (blood glucose, lipids, insulin) and inflammatory markers (C-reactive protein), were assessed. Results: Twenty-five individuals were evaluated. Of them, 14 had acyanotic heart defects and 11 cyanotic heart defects. Mean age was 12.0±3.7 years, and 20 (80%) were male. IPAQ showed that six (24%) individuals were very active, eight (32%) were active, nine (36%) had irregular physical activity, and two (8%) were sedentary. The mean distance walked in the 6MWT, considering all studied individuals, was 464.7±100.4 m, which was 181.4±42.0 m less than the predicted (p=0.005). There was a positive correlation between Z score 6MWT and the number of surgical procedures (r=-0.455; p=0.022). Conclusions: Children and adolescents with congenital heart disease have low functional capacity, but they are not completely sedentary.

Pubertal status of children with congenital heart disease

2021 ◽  
pp. 1-5
Author(s):  
Zahra Ghaemmaghami ◽  
Zahra Khajali ◽  
Mohammad Dalili ◽  
Zahra Fotovati ◽  
Maryam Moradian ◽  
...  
Keyword(s):  
Congenital Heart Disease ◽  
Heart Disease ◽  
Children And Adolescents ◽  
Congenital Heart ◽  
Normal Population ◽  
Large Sample Size ◽  
Pubertal Status ◽  
Major Aspect ◽  
Pubertal Onset ◽  
Pubertal Stages

Abstract Background: CHD influences many aspects of life in affected individuals. Puberty, a major aspect of development, is a concern for patients and families. Objectives: We investigated pubertal status in children and adolescents with CHD. Methods: Patients with CHD aged 6–18 were enrolled. Cardiac diagnoses were confirmed using history, examination, and paraclinical tools including echocardiography. An endocrinologist determined pubertal stages, and the second Tanner stages for pubarche (P2), thelarche (B2), and gonadarche (G2) were considered as the pubertal onset. A study with a large sample size on pubertal onset in a normal population was used for comparison. Results: Totally, 451 patients (228 girls and 223 boys) at a median (10th–90th percentile) age of 10.79 (8.02–14.28) years for the girls and 10.72 (8.05–14.03) years for the boys were enrolled. The median (10th–90th percentile) ages at B2 and P2 in the girls with CHD were 10.77 (9.55–12.68) and 10.53 (9.39–12.28) years, respectively, which were higher than the median ages of 9.74 (8.23–11.94) and 10.49 (8.86–12.17) years in the normal girls. The median (10th–90th percentile) ages at G2 and P2 in the boys with CHD were 11.04 (8.85–13.23) and 11.88 (9.78–13.46) years, correspondingly, which were higher than the median ages of 9.01 (6.00–11.84) and 10.34 (6.84–13.10) years in the normal boys. Conclusions: Pubertal onset could be delayed in children with CHD when compared with the normal population.

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