scholarly journals Assessing the global burden of hemorrhage: The global blood supply, deficits, and potential solutions

2021 ◽  
Vol 9 ◽  
pp. 205031212110549
Author(s):  
Nakul P. Raykar ◽  
Jennifer Makin ◽  
Monty Khajanchi ◽  
Bernard Olayo ◽  
Alejandro Munoz Valencia ◽  
...  

There is a critical shortage of blood available for transfusion in many low- and middle-income countries. The consequences of this scarcity are dire, resulting in uncounted morbidity and mortality from trauma, obstetric hemorrhage, and pediatric anemias, among numerous other conditions. The process of collecting blood from a donor to administering it to a patient involves many facets from donor availability to blood processing to blood delivery. Each step faces particular challenges in low- and middle-income countries. Optimizing existing strategies and introducing new approaches will be imperative to ensure a safe and sufficient blood supply worldwide.

Vaccines ◽  
2019 ◽  
Vol 7 (1) ◽  
pp. 25
Author(s):  
Paul Licciardi ◽  
Ioanna Papadatou

Infections with the bacterium Streptococcus pneumoniae are one of the most common causes of morbidity and mortality in children less than five years of age worldwide, mostly in low- and middle-income countries (LMICs) [...]


Author(s):  
Chau Huynh ◽  
Minh NQ Huynh

Worldwide, 4.8 billion people do not have access to safe, adequate surgical care and anaesthetic management. Surgical care has been deemed “the neglected child of global health,” a startling reminder of the disparities in health services. The provision of surgical interventions can avert 11% of the global burden of disease and 1.5 million deaths each year. Many obstacles exist for low- and middle-income countries (LMIC) to progress towards accessible surgical care. The first challenge is delivering cost-effective surgical care despite financial constraints and political turmoil. Foreign aid was established to alleviate the financial burden and its contributions have been pivotal. However, based on the political climate in certain countries, funds are siphoned to government sectors other than health care. Moreover, the lack of infrastructure, equipment, and personnel in LMIC compound the issue. The other challenge is determining if surgery is as feasible and effective as non-surgical health interventions. Surgical care is crucial and this paper aims to assess the challenges that limit its stature in global health discussions. The paper will address the influence of financing, infrastructure, workforce, service delivery, and information management on surgical care, and the current resolutions, such as humanitarian aid missions.


2016 ◽  
Vol 123 (3) ◽  
pp. 739-748 ◽  
Author(s):  
Tracy Jackson ◽  
Sarah Thomas ◽  
Victoria Stabile ◽  
Matthew Shotwell ◽  
Xue Han ◽  
...  

2018 ◽  
Vol 56 (3) ◽  
Author(s):  
G. A. Roldan ◽  
A. X. Cui ◽  
N. R. Pollock

ABSTRACTIn contrast to the significant resources invested in the diagnosis and prevention ofClostridium difficileinfection (CDI) in resource-rich settings, in resource-limited settings patients with community- and hospital-acquired diarrhea may not routinely be tested for CDI. Is CDI actually less frequent or severe in resource-limited settings, or might we be missing an important opportunity to prevent CDI-related morbidity and mortality (and to promote antibiotic stewardship) in these settings? Here, we review the literature to assess the overall burden of CDI in low- and middle-income countries.


2017 ◽  
Vol 27 (S6) ◽  
pp. S3-S8 ◽  
Author(s):  
Ndidiamaka L. Musa ◽  
Vibeke Hjortdal ◽  
Bistra Zheleva ◽  
Indah K. Murni ◽  
Shunji Sano ◽  
...  

AbstractAn estimated 15 million children die or are crippled annually by treatable or preventable heart disease in low- and middle-income countries. Global efforts to reduce under-5 mortality have focused on reducing death from communicable diseases in low- and middle-income countries with little to no attention focusing on paediatric CHD and acquired heart disease. Lack of awareness of CHD and acquired heart disease, access to care, poor healthcare infrastructure, competing health priorities, and a critical shortage of specialists are important reasons why paediatric heart disease has not been addressed in low resourced settings. Non-governmental organisations have taken the lead to address these challenges. This review describes the global burden of paediatric heart disease and strategies to improve the quality of care for paediatric heart disease. These strategies would improve outcomes for children with heart disease.


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