scholarly journals Neoadjuvant and adjuvant doxorubicin chemotherapy in a case of feline soft tissue sarcoma

2019 ◽  
Vol 5 (2) ◽  
pp. 205511691985787
Author(s):  
Filippo Torrigiani ◽  
Giorgio Romanelli ◽  
Paola Roccabianca ◽  
Elisabetta Treggiari
Keyword(s):  
Soft Tissue ◽  
Soft Tissue Sarcoma ◽  
Surgical Excision ◽  
Mesenchymal Tumour ◽  
Tissue Mass ◽  
History Of ◽  
Local Tumour ◽  
The Right ◽  
Slow Growing

Case summary A 7-year old male neutered domestic shorthair cat was presented with a 2 month history of a slow-growing mass on the right zygomatic area. A CT scan revealed a soft tissue mass in the right zygomatic region with no alterations of the underlying bone and features of local invasiveness. Cytology was suggestive of a mesenchymal tumour and histopathology from an incisional biopsy was consistent with a soft tissue sarcoma (STS). The cat was treated with neoadjuvant intravenous doxorubicin chemotherapy at a dose of 25 mg/m2, every two weeks. The patient experienced a partial response and underwent surgical excision of the tumour. Doxorubicin was continued as an adjuvant treatment for three further chemotherapy sessions, at a dose of 25 mg/m2 every 21 days. Local tumour recurrence was detected on clinical examination and cytologically confirmed 259 days following surgery. Relevance and novel information Treatment with neoadjuvant doxorubicin can be considered in cases of inoperable STSs in order to cytoreduce the tumour and improve the chances of achieving complete surgical margins. The role of adjuvant chemotherapy in this setting remains unclear.

scholarly journals Rare Case of Servelle Martorelle Syndrome

2014 ◽  
Vol 10 (4) ◽  
pp. 91-94
Author(s):  
A Bhatnagar ◽  
M Deshpande
Keyword(s):  
Soft Tissue ◽  
Upper Limb ◽  
Rare Case ◽  
Prompt Treatment ◽  
Congenital Vascular Malformation ◽  
History Of ◽  
The Right ◽  
Scapular Region

Servelle Martorelle Syndrome is a congenital vascular malformation associated with soft tissue hypertrophy and bony hypoplasia. This rarely involves whole of an extremity, with involvement of part of limbs reported in literature. We present a case of a twelve year boy who presented to the Department of Plastic Surgery SGPGIMS in April 2011 ,with history of circumferential soft tissue hypertrophy involving whole of left upper limb, scapular region and axilla since birth. The entire left upper limb length was lesser than the right upper limb. Hence this is a very rare case of Servelle Martorelle Syndrome having extensive limb involvement at a very young age. Highlighted is the role of conservative treatment and close follow-up to understand the natural history of the diseases, with prompt treatment of complications. DOI: http://dx.doi.org/10.3126/kumj.v10i4.11011 Kathmandu Univ Med J 2012;10(4):91-94

scholarly journals Recurrent Episodic Foot-Drop Following Surgery to the Thigh

Sarcoma ◽  
2000 ◽  
Vol 4 (4) ◽  
pp. 183-184 ◽  
Author(s):  
Srinivas Maiya ◽  
Simon Tan ◽  
Robert J. Grimer
Keyword(s):  
Soft Tissue ◽  
Soft Tissue Sarcoma ◽  
Case History ◽  
Surgical Excision ◽  
Left Thigh ◽  
Foot Drop ◽  
Complete Relief ◽  
History Of

Subject.We present the case history of a 47-year-old lady who, 10 months following excision of a soft tissue sarcoma from the left thigh, was struck with recurrent episodes of foot drop.Discussion.The curious phenomenon of recurrent foot drop was found to be secondary to pressure symptoms from a tense seroma of the thigh. She underwent surgical excision of the sac and had immediate and complete relief of symptoms.

scholarly journals Benign cemento-ossifying fibroma: a rare case report

2018 ◽  
Vol 4 (2) ◽  
pp. 585
Author(s):  
Gurbax Singh ◽  
Jasmine Kaur ◽  
Jai Lal Davessar ◽  
Latika Kansal ◽  
Ajay Singh
Keyword(s):  
Sphenoid Sinus ◽  
Rare Case ◽  
Surgical Excision ◽  
Ossifying Fibroma ◽  
Computed Tomography Scan ◽  
Rare Case Report ◽  
History Of ◽  
The Right ◽  
Slow Growing ◽  
Tomography Scan

<p>Cemento-ossifying fibroma (COF) is a benign fibro-osseous lesion commonly seen in the head and neck regions. It is considered as a benign, locally aggressive neoplasm that requires surgical excision. COF has traditionally been considered to be slow growing. We report a case of 11 year-old girl who presented to the ENT Department of our hospital with 7 months history of nasal obstruction, proptosis and headache. Computed Tomography scan images showed a mass in the right nasal cavity. This case is notable because involvement of the sphenoid sinus is rare. </p>

scholarly journals Common swelling of the dorsal thoracic wall brings an unexpected finding: elastofibroma dorsi

2020 ◽  
Vol 90 (1) ◽  
Author(s):  
Sotirios Kotoulas ◽  
Konstantinos Grapatsas ◽  
Charalampos Georgiou ◽  
Zoi Tsilogianni ◽  
Vasileios Leivaditis ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Excisional Biopsy ◽  
Radical Resection ◽  
Thoracic Wall ◽  
Diagnostic Tools ◽  
Unexpected Finding ◽  
Soft Tissue Swelling ◽  
The Right ◽  
Slow Growing

Elastofibroma is a rare benign, soft-tissue slow-growing tumor seen predominantly in elderly females. We present such a case in a 46-year-old female. She presented with gradually increasing soft tissue swelling of 8×6 cm in the right inferior subscapular region. MRI showed a large intramuscular lesion with atypia. She underwent excisional biopsy and the histopathology and immunochemistry showed elastofibroma. We present this rare case to emphasize the important role of the diagnostic tools. A definitive diagnosis helps to avoid unnecessary wide and radical resection.

Floor of mouth schwannoma mimicking a salivary gland neoplasm: a report of the case and review of the literature

2021 ◽  
Vol 14 (2) ◽  
pp. e239452
Author(s):  
Yalda Nassehi ◽  
Arif Rashid ◽  
Gayani Pitiyage ◽  
Rahul Jayaram
Keyword(s):  
Oral Cavity ◽  
Soft Tissue Mass ◽  
Surgical Excision ◽  
Salivary Gland Neoplasm ◽  
Review Of The Literature ◽  
Mri Scan ◽  
Tissue Mass ◽  
Floor Of Mouth ◽  
History Of ◽  
Slow Growing

Schwannomas or neurilemmomas are slow-growing, benign and often firm lumps that are typically painless. They are extremely rare in the oral cavity, with the tongue and the palate being the most common intraoral sites. This is a case report of this pathology in the floor of the mouth. We present a case of a 28-year-old female patient with a 2-month history of a floor of mouth swelling. On clinical examination this was non-tender and appeared firm. An ultrasound of the lesion was performed which revealed a well-defined, rounded and low reflective soft tissue mass. Following an MRI scan and surgical excision of the lesion, a definitive diagnosis of a schwannoma was made. The presence of schwannoma in the oral cavity is unusual. Based on the literature and the presented case, it should be considered as a differential diagnosis until the final histopathological confirmation.

scholarly journals Recurrent neck myxofibrosarcoma: a case report 

2021 ◽  
Vol 15 (1) ◽  
Author(s):  
Chiara Pagnoni ◽  
Luca Improta ◽  
Rossana Alloni ◽  
Francesco Mallozzi Santa Maria ◽  
Irene Aprile ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Soft Tissue Sarcoma ◽  
Distant Metastasis ◽  
Disease Free Survival ◽  
Surgical Excision ◽  
High Recurrence Rate ◽  
Combined Treatments ◽  
Referral Center ◽  
History Of

Abstract Background Myxofibrosarcoma (MFS) is a rare soft tissue sarcoma with a high recurrence rate and a low risk of distant metastasis. It occurs mainly in the extremities of elderly men. Head and neck MFS is extremely rare. Surgery is the cornerstone of treatment. The role of radiotherapy (RT) and chemotherapy (CHT) on MFS is still debated. Case presentation A 67-year-old Caucasian man presented to our sarcoma referral center (SRC) with a history of MFS of the neck excised with microscopic positive surgical margins in a non-referral center. Staging imaging exams did not reveal distant metastasis. After a multidisciplinary discussion, preoperative RT was administered with a total dose of 50 Gy followed by wide surgical excision. Histological examination was negative for viable tumor cells. No relapse occurred during the 24-month postoperative follow-up. Conclusions The case described suggests the importance of planned combined treatments with both RT and surgery for high-grade soft tissue sarcoma. RT seems to be promising within this specific histotype. Close follow-up is advisable in all cases. Further studies are needed to confirm if the observed efficacy of combined treatments results in a prolonged time of disease-free survival and overall survival.

scholarly journals Non-rhabdomyosarcoma soft tissue sarcoma in a neonate, a rare and aggressive disease: case report

2018 ◽  
Vol 6 (1) ◽  
pp. 209
Author(s):  
Tanvi Khanna ◽  
Kunal Das ◽  
B. P. Kalra
Keyword(s):  
Soft Tissue ◽  
Soft Tissue Sarcoma ◽  
Anterior Abdominal Wall ◽  
Soft Tissue Mass ◽  
Soft Tissue Sarcomas ◽  
Surgical Excision ◽  
Tissue Mass ◽  
Disease Case ◽  
Variable Success ◽  
Rare Group

Neonatal soft tissue sarcomas are a rare group of tumors. The behavior and aggressiveness of neonatal STS is variable. Surgical excision has been noted to be most important factor affecting outcome. However, when non-mutilating surgery is not possible, or resection is incomplete, chemotherapy and radiotherapy have been tried with variable success. We encountered a case of a neonate having large soft tissue mass at anterior abdominal wall. Biopsy and immunohistochemistry confirmed it as undifferentiated soft tissue sarcoma. Surgical excision was incomplete with margin positivity. His disease showed recurrence in short duration of time and despite adjuvant chemotherapy, progression was noted. The child abandoned the treatment and died within 3 months of life.

Soft Tissue Sarcoma: The Important Role of Initial MRI Reports for Disease Control

2020 ◽  
Author(s):  
S Weiß ◽  
A Korthaus ◽  
K-H Frosch ◽  
C Schlickewei ◽  
M Priemel
Keyword(s):  
Soft Tissue ◽  
Soft Tissue Sarcoma ◽  
Disease Control

Hepatic brucelloma: a rare complication of a common zoonotic disease

2020 ◽  
Vol 13 (12) ◽  
pp. e237076
Author(s):  
George Vatidis ◽  
Eirini I Rigopoulou ◽  
Konstantinos Tepetes ◽  
George N Dalekos
Keyword(s):  
Rare Complication ◽  
Surgical Excision ◽  
Coombs Test ◽  
Inflammation Markers ◽  
Laboratory Findings ◽  
Ct Guided ◽  
Rare Manifestation ◽  
Bone Marrow Cultures ◽  
History Of ◽  
The Right

Hepatic brucelloma (HB), a rare manifestation of brucellosis, refers to liver involvement in the form of abscess. A 35-year-old woman stockbreeder was admitted due to 1-month history of evening fever, sweating and weight loss, while she was on 3-week course of rifampicin/doxycycline for suspected brucellosis. On admission, she had hepatosplenomegaly and a systolic murmur, while cholestasis, increased inflammation markers and a strong-positive Wright-Coombs test were the main laboratory findings. As blood and bone marrow cultures were unrevealing, further investigation with CT imaging showed a central liver calcification surrounded by heterogeneous hypodense area being compatible with HB. Material from CT-guided drainage tested negative for Brucella spp. After failure to improve on a 10-week triple regiment, surgical excision was decided and Brucella spp were identified by PCR. Our case highlights challenges in establishing HB diagnosis, which should be considered on the right epidemiological context and when serological and radiological evidence favour its diagnosis.

Role of centers with different patient volumes in the management of rhabdomyosarcoma. An analysis by the Italian Pediatric Soft Tissue Sarcoma Committee

2021 ◽  
Author(s):  
Gianni Bisogno ◽  
Giovanna Congiu ◽  
Maria Carmen Affinita ◽  
Giuseppe Maria Milano ◽  
Ilaria Zanetti ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Soft Tissue Sarcoma
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