scholarly journals Cross-reactivity in Skin Prick Test Results of Members Within Pooideae Subfamily

OTO Open ◽  
2021 ◽  
Vol 5 (1) ◽  
pp. 2473974X2098656
Author(s):  
Brette C. Harding ◽  
Brian P. Kinealy ◽  
Christine B. Franzese
Keyword(s):  
Allergic Rhinitis ◽  
Skin Prick Test ◽  
Skin Prick Testing ◽  
Cross Reactivity ◽  
Positive Skin Prick Test ◽  
Test Results ◽  
Positive Skin ◽  
Prick Test ◽  
Timothy Grass ◽  
Representative Member

Objective Molecular similarities of grass pollen antigens have led to the view that cross-reactivity exists within members of the Pooideae subfamily of grasses. This has resulted in testing for only the most antigenically representative member of Pooideae, Timothy grass ( Phleum pratense), despite little literature to support the claim that Phleum is the most representative member or that in vitro cross-reactivity correlates with in vivo cross-reactivity. The aim of the study was to determine if patients with allergic rhinitis symptoms and positive skin prick test results to meadow fescue ( Festuca pratensis) also have positive results to Timothy grass. Study Design Retrospective cross-sectional study. Setting Tertiary care center in middle Missouri. Methods A retrospective chart review identified patients ≥12 years old with a diagnosis of allergic rhinitis who underwent skin prick testing between March 2016 and July 2018, by using a search with CPT code 95004 ( Current Procedural Terminology). Positive skin prick test results were based on wheal produced ≥3 mm than the negative control. Results After review of 2182 charts, 1587 patients met criteria to test for Phleum and Festuca. In total, 1239 patients had a positive result for Phleum or Festuca. Of these, 479 (38.6%) tested positive for Festuca alone, while 342 (27.6%) and 418 (33.7%) tested positive for Phleum alone and Phleum+ Festuca, respectively. Conclusion Clinical cross-reactivity among Pooideae members may not be as complete as traditionally thought. P pratense may not be the most antigenically representative subfamily member, and other grasses may need to be included in skin prick testing.

scholarly journals Food allergies in children: a comparison of parental reports and skin prick test results

2018 ◽  
Vol 58 (2) ◽  
pp. 59-65
Author(s):  
Camilia Metadea Aji Savitri ◽  
Azwin Mengindra Putera Lubis ◽  
Gatot Soegiarto
Keyword(s):  
Skin Prick Test ◽  
Skin Prick Testing ◽  
Food Allergies ◽  
P Value ◽  
Positive Skin Prick Test ◽  
Test Results ◽  
Cross Sectional ◽  
Positive Skin ◽  
Prick Test ◽  
Parental Reports

Background Food allergy is common in children and its prevalence is generally on the rise. Imprecise parental reports about reactions to particular foods can lead to unnecessary restrictions. Since children have specific growth requirements, such nutritional restrictions may have disturbing effects on children’s growth and development.Objective To compare parental reports on food reactions to skin prick test results in their children.Method Retrospective, cross sectional study using patient’s medical record data during one-year study period. Data were analyzed manually and statistically, to assess the degree of agreement (Kappa’s coefficient) and significance (P).Results We collected data from 154 subjects aged 0-18 years. For every allergen assessed, parents reported more food reactions than positive skin prick test results. Allergy incidence were caused, in order, by cow’s milk and chicken (25.3%), eggs (22.1%), chocolate (20.1%), fruits (14.3%), seafood (13%), and saltwater fish (1.9%). Kappa coefficient are all poor (<0.2) and P value are all >0.05 except for chicken (P=0.02).Conclusion Most parents tend to overestimate which food cause reactions in their children, as reactions reported were not necessarily allergenic. Therefore, every patient experiencing allergy reactions should undergo skin prick testing to confirm the possibility of allergy.

scholarly journals Soy Skin Prick Test in Patients with Physician-Diagnosed Atopic Disorders

QJM ◽  
2020 ◽  
Vol 113 (Supplement_1) ◽  
Author(s):  
S M Reda ◽  
N M Radwan ◽  
H R Abdelghany
Keyword(s):  
Allergic Rhinitis ◽  
Skin Prick Test ◽  
Soy Protein ◽  
Total Serum ◽  
Positive Skin Prick Test ◽  
Positive Skin ◽  
Female Ratio ◽  
Serum Ige ◽  
Prick Test ◽  
Protein Sensitization

Abstract Background Soy protein is an important component of soybeans and is one the 8 most significant food allergens. Yet, the prevalence of soy allergy in the pediatric population is not well defined. Objectives To evaluate the incidence of IgE mediated soy protein sensitization among children with clinical manifestation of atopic disorders by the use of skin prick test (SPT) for soy protein. Methods Two hundred patients with atopic manifestations attending the Pediatric Allergy and Immunology Clinic at the Pediatric Department of Ain shams University, were recruited between January 2017 till January 2018. They were subjected to SPT to soy protein, measurement of total serum IgE and eosinophilic count in the peripheral blood. Results Of the 200 patients, 108 (54%) were males and 92 (46%) were females with a male to female ratio of 1.17:1. Their ages ranged between 2 years and 15 years (mean±SD; 6.0±33.3 years). Seven patients (3.5%) had positive skin prick test to soy protein. The mean value for the absolute eosinophilic count was 0.4x109/L. The median for the total serum IgE level was 50 IU/L. According to age, the highest percentage of soy protein sensitivity was elicited among patients less than 3 years (57.14%), followed by those between 3 to 6 years (28.5%) and those between 6 and 15 years (14.28%). A positive family history of atopy was recorded in 122 (61%) of all cases. In terms of gender, incidence of soya sensitivity was higher among males than females but with no statistical difference. Although the most common allergic manifestations of all studied patients were respiratory (83%), and atopic dermatitis (22.5%), yet positive SPT to soy proteins was elicited in 43% in allergic rhinitis cases, in 29% of asthma patients, in 14% of patients with combined asthma and allergic rhinitis, and 14.3% of patients having eczema. Conclusion Soy protein sensitization is not uncommon in children especially in those with atopic manifestations. Large scale studies are needed to evaluate the actual incidence of soy protein hypersensitivity in children.

The effect of allergic rhinitis with positive skin prick test on choroidal thickness

2017 ◽  
Vol 274 (6) ◽  
pp. 2477-2481
Author(s):  
Alper Yenigun ◽  
Ahmet Elbay ◽  
Remzi Dogan ◽  
Orhan Ozturan ◽  
Mehmet Hakan Ozdemir
Keyword(s):  
Allergic Rhinitis ◽  
Skin Prick Test ◽  
Choroidal Thickness ◽  
Positive Skin Prick Test ◽  
Positive Skin ◽  
Prick Test

Maternal positive skin prick test results and asthma prediction after early childhood wheezing

2007 ◽  
Vol 98 (6) ◽  
pp. 540-545 ◽  
Author(s):  
Arnon Elizur ◽  
Noam Pollack ◽  
Sarah E. Boslaugh ◽  
Yakar Kannai ◽  
Yitzhak Katz
Keyword(s):  
Early Childhood ◽  
Skin Prick Test ◽  
Positive Skin Prick Test ◽  
Test Results ◽  
Positive Skin ◽  
Prick Test

scholarly journals Comparison of skin prick allergy test in urban and rural children

2011 ◽  
Vol 51 (2) ◽  
pp. 84
Author(s):  
Fakhri Widyanto ◽  
Rita Evalina Rusli ◽  
Muhammad Ali ◽  
Melda Deliana ◽  
Lily Irsa ◽  
...  
Keyword(s):  
Skin Prick Test ◽  
House Dust ◽  
Urban Areas ◽  
House Dust Mites ◽  
Rural Children ◽  
Positive Skin Prick Test ◽  
Test Results ◽  
Positive Skin ◽  
Prick Test ◽  
Allergy Test

Background Children who grow up in rural areas have a lower incidence of atopy and other allergic manifestations than children in urban areas. Several recent studies have suggested that agricultural exposure may protect children from developing asthma and atopy, but these findings are inconsistent.Objective To examine an association between living in rural or urban areas and skin prick allergy test results in children and to detennine associated risk factors for atopy.Methods We conducted a cross-sectional study in Karo district (rural) and Medan (urban) in October-December 2009. We enrolled primary school children who had a history of atopy in their families. Skin prick testing was done on the volar side of the forearm and included eight aero-allergens: house dust mites, house dust, cotton, chicken feathers, cat dander, cockroaches, mould, and pollen. We analyzed the folloMng risk factors forassociation Mth atopy: tobacco smoke, pets, livestock exposure, and having older sibling(s).Results We recruited 49 children from the Karo district and 52 children from the city of Medan. There were significant associations between living in an urban area and positive skin prick test results for house dust mites and house dust compared to living in a rural area (P=0.04, 95% CI: 1.11 to 5.91; P=0.04, 95% CI: 1.13 to 12.45, respectively). The reverse was true for cockroach allergens (P=0.02, 95% CI: 0.16 to 0.81). Tobacco smoke and livestock exposure were associated Mth negative skin prick test results in rural children (P=O.03, 95% CI: 0.03 to 0.81 and P=0.002, 95% CI: 0.02 to 0.42, respectively). Multivariate analysis revealed that lack of livestock exposure was the major risk factor associated Mth any positive skin prick test results in rural children (P=0.004; 95% CI ; 0.02 to 0.49).Conclusion There were differing associations between living in rural and urban areas to various skin prick test results in children. Lack of livestock exposure was the risk factor associated with positive skin prick test results in rural children.

Impact of Allergic Rhinitis on Voice in Children

ORL ◽  
2021 ◽  
pp. 1-6
Author(s):  
Serap Sahin Onder ◽  
Fatih Savran ◽  
Burak Karabulut ◽  
Mehmet Surmeli ◽  
Aysen Cetemen
Keyword(s):  
Allergic Rhinitis ◽  
Skin Prick Test ◽  
Fundamental Frequency ◽  
Diagnostic Process ◽  
Control Group ◽  
Positive Skin Prick Test ◽  
Voice Change ◽  
Positive Skin ◽  
Prick Test ◽  
Maximum Phonation Time

Introduction: The purpose of the present study was to determine the possible effect of allergic rhinitis (AR) on voice change in children with acoustic analysis and Turkish children’s voice handicap index-10 (TR-CVHI-10). Methods: This is a case-control study. Forty-one children with AR, and a positive skin prick test, as well as 39 children of controls who had produced a negative skin prick test and lacked a history of allergic disease, were selected for the study. Each assessment included recordings for the purposes of acoustic voice analysis (fundamental frequency [f0], jitter %, shimmer %, and harmonics-to-noise ratio (HNR)), and aerodynamic analysis (maximum phonation time (MPT) and s/z ratio). All participants completed TR-CVHI-10. Results: The mean TR-CVHI-10 score of the AR group was significantly higher than the control group (p = 0.013). No difference was observed between the AR and control groups in terms of jitter, shimmer, HNR, and MPT values and s/z ratio (p > 0.05). Conversely, the f0 value was more pronounced in controls (270.9 ± 60.3 Hz) than in the AR group (237.7 ± 54.3 Hz) (p = 0.012). Conclusion: The study’s results revealed that AR can have an effect on fundamental frequency and voice quality in children. The diagnostic process should include AR as a potential cause of voice disorders in children.

scholarly journals Utilising a Skin Prick Test for the determination of the presence of allergic rhinitis in divers

2018 ◽  
Vol 65 (4) ◽  
pp. 49-54
Author(s):  
Romuald Olszański ◽  
Zbigniew Dąbrowiecki ◽  
Dorota Niewiedział ◽  
Krzysztof Gadomski ◽  
Ewa Zieliński
Keyword(s):  
Allergic Rhinitis ◽  
Skin Prick Test ◽  
Allergic Diseases ◽  
House Dust Mites ◽  
Type I ◽  
Positive Skin Prick Test ◽  
List Type ◽  
Positive Skin ◽  
Prick Test ◽  
Diving Accidents

Abstract Allergic rhinitis occurs in various regions of the world and affects from 10 to 40% of the population. The skin prick test is the “gold standard” for the detection of type I allergic diseases according to the Gella and Coombs classification, which is mediated by IgE. For our experiment, skin prick tests were performed on 60 divers aged between 30 and 40 years of age. The following tests for airborne allergens were used: tests for pollen from trees, grasses, cereals, weeds, proteins from house dust mites, animal hair and epidermis, and moulds. On the basis of an interview and a positive skin prick test allergic rhinitis was diagnosed in 17 divers. Conclusions: Allergic rhinitis can cause health problems in divers and be the cause of diving accidents. The application of the skin prick test during the health qualification in the Military Maritime Health Commission, would allow the exclusion of diver candidates suffering from allergies.

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