scholarly journals An image analysis system for cervical cytology automation using nuclear DNA content.

1979 ◽  
Vol 27 (1) ◽  
pp. 613-620 ◽  
Author(s):  
J H Tucker

An experimental computer/image analysis system has been used to investigate cytology automation techniques based on nuclear DNA measurement and morphological artefact rejector tests. The system automatically measures and normalizes the integrated optical density of cell nuclei in specially prepared cervical cytology specimens, and selects any objects with abnormally high values for further analysis. These are then analyzed by morphological and densitometric tests designed to eliminate false positive signals caused by non-nuclear artefacts. The coordinates of the remaining abnormal nuclei are recorded so that they can subsequently be relocated and examined by a cytotechnician. Preliminary results are given showing the measurement accuracy of the system and the performance of the artefact rejection tests.

2006 ◽  
Vol 37 (8-9) ◽  
pp. 321-325 ◽  
Author(s):  
Mario Ribeiro De Melo ◽  
Jorge Luiz Araújo Filho ◽  
Vasco José Ramos Patu ◽  
Marcos Cezar Feitosa Machado ◽  
Luciano Albuquerque Mello ◽  
...  

2019 ◽  
Vol 13 (1) ◽  
pp. 109-116 ◽  
Author(s):  
Yuki Fujihara ◽  
Shigeo Fukunishi ◽  
Tomokazu Fukui ◽  
Shoji Nishio ◽  
Yu Takeda ◽  
...  

Introduction: We have developed and utilized the Gravity-guide (G-guide) as a simple manual instrument for intraoperative assessment and adjustment of stem anteversion (AV). Since 2013, we simultaneously measured stem AV using the G-guide and image-free navigation during THA procedure. The purpose of this study was to compare the measurement accuracy of the G-guide and navigation system using the postoperative CT results as a reference. Methods: In total, 59 hips in 56 patients who underwent primary THA using both the G-guide and image-free navigation system were included in the study. All patients underwent postoperative CT examination, and the femoral stem AV was assessed using a 3D image analysis system (Zed hip, LEXI, Japan). The AV angle derived from the postoperative CT image analysis was used as the reference value to assess the accuracy of the two intraoperative measurement systems. Results: The discrepancy between the G-guide and the postoperative CT-measured values averaged 5.0° ± 3.9°, while the corresponding value for the navigation system was 5.2° ± 4.1°. Acceptable accuracy with a measurement error of less than 10° was achieved in 86% and 90% of the cases for the G-guide and navigation measurements respectively. Conclusion: Consequently, it was shown that both navigation and G-guide measurements can achieve comparative accuracy and are clinically useful.


2021 ◽  
Vol 2021 ◽  
pp. 1-11
Author(s):  
Chunfeng Wang ◽  
Caigang Peng ◽  
Yepo Hou ◽  
Minmin Chen

The important application of computer imaging technology in the medical field is a necessary auxiliary method for clinical diagnosis and treatment. At present, many people are affected by various factors and have various problems caused by the dental cellular bone. Traditional treatment methods are complex and long, which can cause damage to body tissues. Based on this problem, this paper takes the augmented reality measurement of X-ray dental film as the research object. Based on the in-depth measurement algorithm of the computer image analysis system, two three-dimensional reconstruction methods based on the center of gravity and the matching of the front and side positions are proposed. These two methods only need two X-rays of the front and side of the dental film, the three-dimensional parameters are obtained through calculation and analysis of each spine in the X-ray film, and these parameters are used to fit the dental alveolar bone model. The experimental results prove that the computer-based image analysis system has a great effect on the measurement of X-ray dental film alveolar bone. The positive correlation coefficient reaches 0.87. Compared with the cerebral infarction caused by other methods, the proportion of people with dental film alveolar bone injury is about 15%; after treatment, the functional recovery rate reaches more than 80%. Studies have found that there is a great difference in the age of the population that needs to be treated for dental slices and alveolar bone. The grade of patients is generally under 20 and over 60. This shows that the measurement of X-ray dental film alveolar bone based on computer image analysis system can play an important role in protecting people's oral health.


Open Medicine ◽  
2011 ◽  
Vol 6 (5) ◽  
pp. 665-671
Author(s):  
Suzana Otasevic ◽  
Jovana Đorđević ◽  
Gordana Ranđelović ◽  
Aleksandra Ignjatović ◽  
Predrag Stojanović ◽  
...  

AbstractThe aim of the study is to investigate the most frequent cause of superficial mycoses in patients from the territory of city Niš Southeast Serbia in the period from 1998 to 2010. A total of 3223 samples from 2887 patients with suspected dermatomycoses were examined. Superficial mycoses were diagnosed using standard microbiology techniques (conventional microscopy and cultivation). Dermatophytes were determined on the basis of their macroscopic and microscopic morphological and morphometric characteristics. Morphometric characteristics were obtained by Laboratory Universal Computer Image Analysis system (Lucia M, 1996). Species of genus Candida were identified using the test of production of germ tube in sera, by growth on comertial chromatogen medium (Chromotogenic Candida, Liofichem/Bacteriology products, Italy) and by using Auxacolor TMBioRad, France. The results were elaborated with the statistical method of descriptive and quantitative analysis (SPSS 14.0 for Windows 2003). The prevalence of superficial mycoses was 25,1%. Dermatophytes were identified in 67.6% of all positive cultures. Microsporum canis was the most prevalent (50.3%) dermatophyte isolated, followed by Trichophyton metagrophytes var. mentagrophytes (35.4%). Yeast genus Candida has become a more frequent cause of superficial fungal infection since 2001. and C. albicans was the dominant yeast (61.1%).


2005 ◽  
Vol 79 (3) ◽  
pp. 217-225 ◽  
Author(s):  
M.A. Valero ◽  
M. Panova ◽  
S. Mas-Coma

AbstractKnowledge of the morphological phenotypes of the liver fluke Fasciola hepatica (Trematoda: Digenea) is analysed. The influence of parasite age on its dimensions, the adult fluke growth model, variation in a biometric variable versus time, and variation in a biometric variable versus another biometric variable (allometric model) are revised. The most useful allometric model appears to be (y2m]#x2212;y2)/y2=c [(y1m−y1)/y1]b, where y1=body area or body length, y2=one of the measurements analysed, y1m, y2m=maximum values towards which y1 and y2, respectively, tend, and c, b=constants. A method based on material standardization, the measurement proposal and allometric analysis is detailed. A computer image analysis system (CIAS), which includes a colour video-camera connected to a stereomicroscope (for adult studies) and a microscope (for egg studies), facilitates the processing of digital imaging. Examples of its application for the analysis of the influence of different factors on the liver fluke phenotype are shown using material from the Northern Bolivian Altiplano, where human and domestic animal fascioliasis is caused by F. hepatica only. Comparisons between the development of livestock fluke populations from highlands and lowlands are discussed and the relationships between host species and liver fluke morphometric patterns is analysed.


2012 ◽  
Vol 5 (1) ◽  
pp. 58-61 ◽  
Author(s):  
Gholamreza Mowlavi ◽  
Mitra Salehi ◽  
Mohammadreza Eshraghian ◽  
Mohammad Bagher Rokni ◽  
Majid Fasihi-Harandi ◽  
...  

1979 ◽  
Vol 27 (1) ◽  
pp. 629-634 ◽  
Author(s):  
I Al ◽  
J S Ploem

In slide based automation of cervical cytology the first stage of analysis involves finding possibly suspicious cells, or areas on the slide with these types of cells. By using a television based system such as the Leyden Television Analysis System (LEYTAS), a number of detection methods can be applied to rapidly screen a large number of fields automatically for suspicious cells. In this paper, results using a parameter based on increased nuclear DNA content of cells are given and a second detection method based on a chromatin pattern feature, called chromatin contrast, is discussed. Two blind trials on 41 positive and 22 negative cervical slides, using the Leyden Television Analysis System to detect suspicious cells with an increased nuclear DNA content, were promising. In 1 of the 41 positive cases no suspicious cells were found. In the negative specimens, suspicious cells were detected in 1 of 9 cases and 1 of 13 cases, with the two detection parameters investigated. These findings are discussed and some automatic artefact rejection procedures with preliminary results are given.


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