MULTIDRUG-RESISTANT TUBERCULOSIS: A REVIEW OF THE 23 CASES TREATED BY THE SAINT-PIERRE UNIVERSITY HOSPITAL (BRUSSELS)

2009 ◽  
Vol 64 (2) ◽  
pp. 113-119 ◽  
Author(s):  
V. Jacob ◽  
L. Robert ◽  
C. Lebrun ◽  
Y. Van Laethem ◽  
R. Sergysels
Keyword(s):  
Multidrug Resistant ◽  
University Hospital ◽  
Resistant Tuberculosis ◽  
Multidrug Resistant Tuberculosis

GeneXpert contribution in the diagnosis of multi-resistant tuberculosis in new cases at the National University Hospital Centre of Pneumo-Phtisiology of Cotonou (Benin)

2021 ◽  
Vol 1 (2) ◽  
pp. 038-042
Author(s):  
Hebert Dedehouanou ◽  
Yazid Taïrou Toure ◽  
Laurence Yehouenou
Keyword(s):  
Pulmonary Tuberculosis ◽  
Multidrug Resistant ◽  
University Hospital ◽  
Molecular Diagnostic ◽  
The Third ◽  
Resistant Tuberculosis ◽  
Multidrug Resistant Tuberculosis ◽  
National University ◽  
Age Range ◽  
Limited Sensitivity

The diagnosis of bacteriologically confirmed pulmonary tuberculosis in Benin and in other developing countries relies on the search for acid-fast bacilli through microscopy despite its limited sensitivity. The objective of this study is to evaluate the contribution of the Xpert test in the diagnosis of multidrug-resistant tuberculosis in all new suspects received at the Centre National Hospitalier Universitaire de Pneumo-Phtisiologie de Cotonou (CNHU-PPC) of Benin. The biological material consisted of sputum from new suspected TB patients received at CNHU-PPC during the third quarter of 2018. A total of two thousand three hundred and seventy-five (2375) suspected patients were included in the study, of which 52% were men and 48% were women. The most representative age range was 15-24 years, 28%. GeneXpert was able to diagnose pulmonary tuberculosis in 10.02% of patients, including 9.7% rifampicin-susceptible and 0.3% rifampicin-resistant patients who could not be detected by microscopy. This molecular diagnostic tool is of great value for the diagnosis of multidrug-resistant tuberculosis in new suspects.

scholarly journals Profil De Résistance Des Mycobabcterium Tuberculosis Des Malades En Retraitement Dans La Région De Haute Matsiatra, Madagascar

2017 ◽  
Vol 13 (18) ◽  
pp. 465
Author(s):  
Ravahatra Kiady ◽  
Rakotondrabe Iantsotiana Davidson ◽  
Rasoafaranirina Marie Odette ◽  
Tiaray Harison Michel ◽  
Nandimbiniaina Anjara ◽  
...  
Keyword(s):  
Mycobacterium Tuberculosis ◽  
Control Program ◽  
Multidrug Resistant ◽  
University Hospital ◽  
Tuberculosis Control ◽  
Resistant Tuberculosis ◽  
Multidrug Resistant Tuberculosis ◽  
Study Results ◽  
Resistant Strains ◽  
The University

Introduction: Relapse, failure and defaulted treatment are a risk factor for Mycobacterium tuberculosis resistance to anti-tuberculosis. The objective of our study is to determine the resistance profile of Mycobacterium tuberculosis of patients in retreatment at the Haute Matriatra area. Method: This is a retrospective, descriptive study carried out on the basis of the data contained in the register of the Haute Matsiatra Regional Tuberculosis Laboratory of the University Hospital of Fianarantsoa, from May 2014 to December 2016 (31 months). We included patients with retreatment in the study. Results: We found 138 patients in retreatment. The average age was 39.32 years with a sex ratio of 2.11. Resistance to Rifampicin and Isoniazid was respectively 2.17% and 2.82%, The prevalence of multidrug-resistant tuberculosis was 0.72%. Conclusion: Tuberculosi resistance, monoresistance or multidrug resistance is a reality in the region of Haute Matsiatra with a prevalence that is still low, reflecting the effectiveness of the tuberculosis control program. However, monoresistances require special attention and monitoring to avoid the emergence of multidrug resistant strains.

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