scholarly journals Single-cell molecular analysis defines therapy response and immunophenotype of stem cell subpopulations in CML

Blood ◽  
2017 ◽  
Vol 129 (17) ◽  
pp. 2384-2394 ◽  
Author(s):  
Rebecca Warfvinge ◽  
Linda Geironson ◽  
Mikael N. E. Sommarin ◽  
Stefan Lang ◽  
Christine Karlsson ◽  
...  

Key Points Single-cell gene expression analysis reveals CML stem cell heterogeneity and changes imposed by TKI therapy. A subpopulation with primitive, quiescent signature and increased survival to therapy can be high-purity captured as CD45RA−cKIT−CD26+.

2017 ◽  
Vol 27 (11) ◽  
pp. 1783-1794 ◽  
Author(s):  
Jiaxu Wang ◽  
Piroon Jenjaroenpun ◽  
Akshay Bhinge ◽  
Vladimir Espinosa Angarica ◽  
Antonio Del Sol ◽  
...  

2010 ◽  
Vol 18 (4) ◽  
pp. 675-685 ◽  
Author(s):  
Guoji Guo ◽  
Mikael Huss ◽  
Guo Qing Tong ◽  
Chaoyang Wang ◽  
Li Li Sun ◽  
...  

2013 ◽  
Vol 15 (4) ◽  
pp. 363-372 ◽  
Author(s):  
Victoria Moignard ◽  
Iain C. Macaulay ◽  
Gemma Swiers ◽  
Florian Buettner ◽  
Judith Schütte ◽  
...  

2017 ◽  
Vol 97 (1) ◽  
pp. 5-17 ◽  
Author(s):  
Qingqing Wei ◽  
Liang Zhong ◽  
Shaopeng Zhang ◽  
Haiyuan Mu ◽  
Jinzhu Xiang ◽  
...  

RSC Advances ◽  
2015 ◽  
Vol 5 (7) ◽  
pp. 4886-4893 ◽  
Author(s):  
Hao Sun ◽  
Tim Olsen ◽  
Jing Zhu ◽  
Jianguo Tao ◽  
Brian Ponnaiya ◽  
...  

Gene expression analysis at the single-cell level is critical to understanding variations among cells in heterogeneous populations.


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