A monoclonal antibody-defined membrane antigen complex is required for neutrophil-neutrophil aggregation
Keyword(s):
Abstract We examined the aggregation responses of normal neutrophils treated with the murine monoclonal antibody (MoAb) 60.3. Addition of MoAb 60.3 to normal neutrophils produced dose-dependent inhibition of neutrophil aggregation in response to phorbol myristate acetate, zymosan-activated plasma, and N-formyl-methionylleucylphenylalanine. We conclude that the membrane glycoprotein complex recognized by MoAb 60.3--designated CDw18- -is required for neutrophil-neutrophil aggregation in vitro.
2015 ◽
Vol 59
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pp. 2867-2874
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1986 ◽
Vol 22
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pp. 443-447
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2014 ◽
Vol 2014
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pp. 1-9
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2000 ◽
Vol 44
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pp. 3302-3305
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1988 ◽
Vol 255
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pp. F43-F48
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1993 ◽
Vol 264
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pp. F882-F890
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