Delayed sputum smear conversion due to cigarette smoking in active pulmonary tuberculosis

2016 ◽  
Author(s):  
Islam Mejri Ep Ajili ◽  
Soumaya Ben Saad ◽  
Achref Ben Tkhayet ◽  
Hafaoua Daghfous ◽  
Fatma Tritar
Keyword(s):  
Cigarette Smoking ◽  
Pulmonary Tuberculosis ◽  
Sputum Smear ◽  
Active Pulmonary Tuberculosis

scholarly journals Effect of cigarette smoking on sputum smear conversion in adults with active pulmonary tuberculosis

2005 ◽  
Vol 99 (4) ◽  
pp. 415-420 ◽  
Author(s):  
A.T. Abal ◽  
B. Jayakrishnan ◽  
S. Parwer ◽  
A. El Shamy ◽  
E. Abahussain ◽  
...  
Keyword(s):  
Cigarette Smoking ◽  
Pulmonary Tuberculosis ◽  
Sputum Smear ◽  
Active Pulmonary Tuberculosis

Nutrient Supplementation as Adjunct Therapy in Pulmonary Tuberculosis

2004 ◽  
Vol 74 (2) ◽  
pp. 144-146 ◽  
Author(s):  
Chandra
Keyword(s):  
Trace Elements ◽  
Pulmonary Tuberculosis ◽  
Trace Element ◽  
Acid Fast Bacillus ◽  
Sputum Smear ◽  
Nutrient Supplementation ◽  
Active Pulmonary Tuberculosis ◽  
Confounding Variables ◽  
Number Of Individuals ◽  
To Receive

The study examined the effect of supplementation with multivitamins and trace elements on microbiological and radiological recovery in patients with pulmonary tuberculosis. Forty-four patients aged 28–50 years were diagnosed with active pulmonary tuberculosis based on X-ray of the chest and smear examination of the sputum for the presence of acid-fast bacilli. They were all treated for six months with a standard anti-tuberculosis regimen that has been found to be effective worldwide for disease control. The subjects were randomized to receive either a multivitamin-trace element supplement or a placebo containing calcium. The two groups were matched on all relevant confounding variables. At two months into the treatment, the group that was supplemented with a multivitamin-trace element preparation showed a significant reduction in the number of individuals with sputum smear positive for acid-fast bacillus: two out of 22 individuals, compared with seven out of 22 among placebo-treated controls (p = 0.028, Fisher’s test). It is concluded that patients with tuberculosis should be supplemented with a suitable micronutrient preparation that contains optimum amounts of all vitamins and trace elements that have been documented to enhance the immune response.

scholarly journals Enhancement of Diagnostic Efficiency by a Gamma Interferon Release Assay for Pulmonary Tuberculosis

2008 ◽  
Vol 15 (6) ◽  
pp. 1028-1030 ◽  
Author(s):  
Kelly Aparecida Kanunfre ◽  
Olavo Henrique Munhoz Leite ◽  
Max Igor Lopes ◽  
Marcelo Litvoc ◽  
Antonio Walter Ferreira
Keyword(s):  
Pulmonary Tuberculosis ◽  
Operating Characteristic ◽  
Characteristic Curve ◽  
Sputum Smear ◽  
Smear Microscopy ◽  
Diagnostic Efficiency ◽  
Active Pulmonary Tuberculosis ◽  
Negative Culture ◽  
Release Assay ◽  
Negative Sputum

ABSTRACT This study was designed to examine the use of the QuantiFERON-TB Gold assay as an aid in the diagnosis of active pulmonary tuberculosis (TB) in Brazilian patients. Using the receiver operating characteristic curve, the cutoff was adjusted to ≥0.20 IU/ml. The sensitivity increased to 86%, with 100% specificity. All TB patients with negative sputum smear microscopy and negative culture results were positive using this test.

scholarly journals Genetic Structure and Drug Susceptibility Patterns ofMycobacterium tuberculosisComplex Strains Responsible of Human Pulmonary Tuberculosis in the Major Rearing Region in Cameroon

2016 ◽  
Vol 2016 ◽  
pp. 1-12 ◽  
Author(s):  
Francioli Koro Koro ◽  
Alphonse Um Boock ◽  
Afi Leslie Kaiyven ◽  
Juergen Noeske ◽  
Cristina Gutierrez ◽  
...  
Keyword(s):  
Genetic Structure ◽  
Pulmonary Tuberculosis ◽  
Drug Susceptibility ◽  
Sputum Smear ◽  
Antituberculosis Drug ◽  
Newly Diagnosed ◽  
Active Pulmonary Tuberculosis ◽  
Proportion Method ◽  
Susceptibility Patterns ◽  
Unique Clone

Background. Cameroon this last decade continues to present a low contribution ofM. africanumandM. bovisin human tuberculosis (TB), whileM. boviswas prevalent in cattle but all these pieces of information only concerned West and Center regions.Methods. We carried out the first study in Adamaoua, one of the most rearing regions of Cameroon, on the genetic structure and drug susceptibility of the MTBC strains isolated from newly diagnosed sputum smear-positive patients aged 15 years and above. For that purpose, spoligotyping, a modified 15 standard MIRU/VNTR loci typing, and the proportion method were used.Results. Four hundred and thirty-seven MTBC isolates were analyzed by spoligotyping. Of these, 423 were identified asM. tuberculosis, within the Cameroon family being dominant with 278 (65.7%) isolates; twelve (2.75%) isolates were classified asM. africanumand two asM. bovis. MIRU/VNTR typing of the most prevalent sublineage (SIT 61) suggested that this lineage is not a unique clone as thought earlier but could constitute a group of strains implicated to different pocket of TB transmission. OnlyM. tuberculosissublineages were associated with antituberculosis drug resistance.Conclusion. These results showed the weak contribution ofM. africanumandM. bovisto human active pulmonary tuberculosis in Cameroon even in the rearing region.

scholarly journals The association between magnitude of T-SPOT.TB and clinical characteristics in active pulmonary tuberculosis: a retrospective multicenter investigation

2019 ◽  
Author(s):  
Yunqing Chang ◽  
Wanli Kang ◽  
Meiying Wu ◽  
A Ertai ◽  
Shucai Wu ◽  
...  
Keyword(s):  
Pulmonary Tuberculosis ◽  
Clinical Characteristics ◽  
Bacterial Culture ◽  
Sputum Smear ◽  
Smear Microscopy ◽  
Positive Trend ◽  
Age Group ◽  
Chi Square ◽  
Active Pulmonary Tuberculosis ◽  
Chi Square Test

Abstract Background: The aim of this study was to evaluate the association between magnitude of T-SPOT.TB and clinical characteristics in active pulmonary tuberculosis. Methods: In this retrospective multicenter investigation, the medical records’ archives of PTB patients were reviewed. Data including gender, age group, bacterial culture, sputum-smear microscopy, lung cavity and range of PTB were extracted from the records. The Jonckheere-Terpstra test and chi-square test for trend were used to evaluate the association between magnitude of T-SPOT.TB and clinical characteristics in active pulmonary tuberculosis. Results: A total of 1252 PTB patients were included in this study.Chi-square trend tests revealed significant positive trends between bacterial culture and magnitude of T-SPOT.TB A (χ2 =18.978, P <0.001) or T-SPOT.TB B (χ2 =19.677, P <0.001). There were significant positive trends between AFB and magnitude of T-SPOT.TB A (TJT =345784, P <0.001) or T-SPOT.TB B (TJT =336017, P <0.001). There was a significant positive trend between range of lung cavity and magnitude of T-SPOT.TB A (TJT =326079.5, P =0.023). There were significant negative trends between age group and magnitude of T-SPOT.TB A (TJT =204306, P <0.001) or T-SPOT.TB B (TJT =206572, P <0.001). Conclusions: The magnitude of T-SPOT.TB in PTB patients may reflect the condition of the patients and could be helpful for clinicians to assess the degree of infection and lung tissue damage.

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