SERUM OSMOLARITY IS ASSOCIATED WITH SEVERITY OF OBSTRUCTIVE SLEEP APNEA SYNDROME: A NOVEL RISK FACTOR FOR CARDIOVASCULAR DISEASE

2018 ◽  
Author(s):  
Asiye Kanbay ◽  
Mustafa Çalışkan ◽  
Halil İbrahim Yakar ◽  
Sebahat Alışır Ecder
Keyword(s):  
Cardiovascular Disease ◽  
Obstructive Sleep Apnea ◽  
Risk Factor ◽  
Sleep Apnea ◽  
Obstructive Sleep Apnea Syndrome ◽  
Sleep Apnea Syndrome ◽  
Serum Osmolarity ◽  
Obstructive Sleep ◽  
Apnea Syndrome

Cardiovascular outcomes of CPAP therapy in obstructive sleep apnea syndrome

2007 ◽  
Vol 293 (4) ◽  
pp. R1666-R1670 ◽  
Author(s):  
Walter T. McNicholas
Keyword(s):  
Cardiovascular Disease ◽  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Obstructive Sleep Apnea Syndrome ◽  
Sleep Apnea Syndrome ◽  
Cpap Therapy ◽  
Obstructive Sleep ◽  
Cardiovascular Morbidity And Mortality ◽  
Apnea Syndrome ◽  
The Impact

Considerable evidence is now available of an independent association between obstructive sleep apnea syndrome (OSAS) and cardiovascular disease. The association is particularly strong for systemic arterial hypertension, but there is growing evidence of an association with ischemic heart disease and stroke. The mechanisms underlying cardiovascular disease in patients with OSAS are still poorly understood. However, the pathogenesis is likely to be a multifactorial process involving a diverse range of mechanisms, including sympathetic overactivity, selective activation of inflammatory molecular pathways, endothelial dysfunction, abnormal coagulation, and metabolic dysregulation, the latter particularly involving insulin resistance and disordered lipid metabolism. Therapy with continuous positive airway pressure (CPAP) has been associated with significant benefits to cardiovascular morbidity and mortality, both in short-term studies addressing specific aspects of morbidity, such as hypertension, and more recently in long-term studies that have evaluated major outcomes of cardiovascular morbidity and mortality. However, there is a clear need for further studies evaluating the impact of CPAP therapy on cardiovascular outcomes. Furthermore, studies on the impact of CPAP therapy have provided useful information concerning the role of basic cell and molecular mechanisms in the pathophysiology of OSAS.

Is obstructive sleep apnea syndrome a risk factor for auditory pathway?

2011 ◽  
Vol 16 (2) ◽  
pp. 413-417 ◽  
Author(s):  
Manuele Casale ◽  
Emanuela Vesperini ◽  
Massimiliano Potena ◽  
Marco Pappacena ◽  
Federica Bressi ◽  
...  
Keyword(s):  
Obstructive Sleep Apnea ◽  
Risk Factor ◽  
Sleep Apnea ◽  
Obstructive Sleep Apnea Syndrome ◽  
Sleep Apnea Syndrome ◽  
Auditory Pathway ◽  
Obstructive Sleep ◽  
Apnea Syndrome

scholarly journals Obstructive sleep apnea syndrome is a risk factor for arterial hypertension

2003 ◽  
Vol 9 (2) ◽  
pp. 37-41
Author(s):  
A. L. Kalinkin
Keyword(s):  
Obstructive Sleep Apnea ◽  
Risk Factor ◽  
Sleep Apnea ◽  
Cardiovascular Diseases ◽  
Arterial Hypertension ◽  
Obstructive Sleep Apnea Syndrome ◽  
Sleep Apnea Syndrome ◽  
Experimental Studies ◽  
Obstructive Sleep ◽  
Apnea Syndrome

The obstructive sleep apnea syndrome (OSAS) is a risk factor for cardiovascular diseases The results of epidemiological, observational, and experimental studies support the fact that OSAS is of considerable importance in the development of arterial hypertension via chronic sympathetic activation and sleep-induced neurohumoral changes OSAS is of prime importance in the development of refractory AH CPAP therapy not only eliminates sleep-induced obstructive respiratory impairments, but frequently lowers blood pressure in hypertensive patients, and improves the prognosis of cardiovascular diseases

scholarly journals Comparison of the Effects of the Somatotype on the Physical Activity, Kinesiophobia, and Fatigue Levels of Obstructive Sleep Apnea Syndrome Patients and Healthy Individuals

2021 ◽  
Author(s):  
Şeyma Toy ◽  
Rukiye Çiftçi ◽  
Deniz Şenol ◽  
Fatma Kizilay ◽  
Hilal Ermiş
Keyword(s):  
Physical Activity ◽  
Obstructive Sleep Apnea ◽  
Risk Factor ◽  
Sleep Apnea ◽  
Obstructive Sleep Apnea Syndrome ◽  
Sleep Apnea Syndrome ◽  
Activity Level ◽  
Healthy Individuals ◽  
Obstructive Sleep ◽  
Apnea Syndrome

Background: We aimed to compare the physical activity, kinesiophobia, and fatigue levels of obstructive sleep apnea syndrome (OSAS) patients and healthy individuals in terms their somatotypes. Methods: A total of 165 individuals were enrolled referred to the Department of Chest Diseases Sleep Disorders Center Outpatient Clinic of Inonu University, Malatya, Turkey in 2018. The somatotype analysis was conducted using the Heath-Carter method, the fatigue level was assessed using the Functional Assessment of Chronic Illness Therapy (FACIT) fatigue scale, the kinesiophobia level was assessed using the Tampa Scale for Kinesiophobia (TSK), and the physical activity level was assessed using the International Physical Activity Questionnaire (IPAQ). Results: The results of the somatotype analysis revealed 3 different somatotypes in the healthy individuals and the OSAS patients’ mesomorph endomorph, endomorphic mesomorph, and mesomorphic endomorph. When comparing the somatotypes of the healthy individuals and the OSAS patients, statistically significant differences were found in the FACIT scores of the mesomorph endomorphs, the IPAQ and FACIT scores of the endomorphic mesomorphs, and the TSK and FACIT scores of the mesomorphic endomorphs (P<0.05). Conclusion: In all three somatotypes of the OSAS patients, the fatigue index scores were higher when compared to those of the healthy individuals. Moreover, when compared with the healthy individuals, the physical activity levels of the endomorphic mesomorphs with OSAS were low, while the kinesiophobia scores of the mesomorphic endomorphs with OSAS were high. Based on the results of this study, in OSAS patients, the endomorphic mesomorph somatotype could be a risk factor for reduced physical activity, while the mesomorphic endomorph somatotype could be a risk factor for increased kinesiophobia.

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