Association between long standing heavy traffic exposure and respiratory symptoms and airway inflammation in older adults and elderly

Author(s):  
Regiani Carvalho Oliveira ◽  
Luís Fernando Amato-Lourenço ◽  
Pamela Souza Almeida ◽  
Bianca B.M. Garcia ◽  
Willian K.M. Vieira ◽  
...  
2021 ◽  
Vol 268 ◽  
pp. 115893
Author(s):  
Regiani Carvalho-Oliveira ◽  
Luís F. Amato-Lourenço ◽  
Pâmela S. Almeida ◽  
Bianca B.M. Garcia ◽  
William K.M. Vieira ◽  
...  

2013 ◽  
Vol 12 (1) ◽  
Author(s):  
Yong Cai ◽  
Rong Shi ◽  
Huijiang Song ◽  
Meili Shang ◽  
Tian Shen ◽  
...  

2020 ◽  
pp. 003693302096289
Author(s):  
Peter Davis ◽  
Rory Gibson ◽  
Emily Wright ◽  
Amy Bryan ◽  
Jamie Ingram ◽  
...  

Introduction: Understanding of how SARS-CoV-2 manifests itself in older adults was unknown at the outset of the pandemic. We undertook a retrospective observational analysis of all patients admitted to older people’s services with confirmed COVID-19 in one of the largest hospitals in Europe. We detail presenting symptoms, prognostic features and vulnerability to nosocomial spread. Methods: We retrospectively collected data for each patient with a positive SARSCoV-2 RT PCR between 18th March and the 20th April 2020 in a department of medicine for the elderly in Glasgow. Results: 222 patients were included in our analysis. Age ranged from 56 to 99 years (mean = 82) and 148 were female (67%). 119 patients had a positive swab for SARS-CoV-2 within the first 14 days of admission, only 32% of these patients presented with primarily a respiratory type illness. 103 patients (46%) tested positive after 14 days of admission – this was felt to represent likely nosocomial infection. 95 patients (43%) died by day 30 after diagnosis. Discussion: This data indicates that older people were more likely to present with non-respiratory symptoms. High clinical frailty scores, severe lymphopenia and cumulative comorbidities were associated with higher mortality rates. Several contributing factors will have led to nosocomial transmission.


Epidemiology ◽  
2007 ◽  
Vol 18 (Suppl) ◽  
pp. S209
Author(s):  
M Escamilla ◽  
A Barraza-Villarreal ◽  
L Hernandez-Cadena ◽  
M Ramirez-Aguilar ◽  
B Del-Río ◽  
...  

Author(s):  
Barbara J. Saavedra Bayona ◽  
Andrés Felipe Sepúlveda Villamil ◽  
Ronal Jackson Sierra Parada ◽  
Luis Camilo Blanco Becerra

The purpose of this article was to establish the association between exposure to particulate matter and respiratory symptoms evaluated in students who remain in schools at the municipality of Guachetá (Colombia). This is a cross-sectional study conducted on children between 4 and 17 years old, in two schools in the municipality of Guachetá. During a period of 11 consecutive working days, using a personal sampling pump and a low-cost real-time sensor, concentrations of PM10 and PM2.5 were measured. A survey was applied to a sample of 276 students, obtaining respiratory symptoms and general data. A prevalence ratio (PR) was estimated to show the possible association between exposure to particulate matter and respiratory symptoms. The school with the highest concentrations of particulate matter presented a possible association with all the respiratory symptoms evaluated in the school facilities, with a PR of 3.05 (95%CI:1.62-5.76) for cough, 1.85 (95%CI:1.06-3.24) for phlegm, 5.12 (95%CI:2.17-12.07) for shortness of breath, 3.83 (95%CI:2.07-7.10) for sneezing and 2.25 (95%CI:1.12-4.54) for dry nasal passages. In conclusion, children who are located in the school closest to a coke furnace and disrepair roads where heavy traffic circulates, are possibly associated with the presence of respiratory symptoms during their stay in the school facilities. For living in the urban area, cooking with firewood or charcoal, and living with smokers at home, a possible association with the evaluated respiratory symptoms was found.


Author(s):  
Ruth Wiggans ◽  
Jade Sumner ◽  
Edward Robinson ◽  
Alison Codling ◽  
Lisa Bradshaw ◽  
...  

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