The effects of timing of fine needle aspiration biopsies on gene expression profiles in breast cancers

Breast cancer has been considered a female dominated disease. Carcinoma of male breast is a rare disease representing 1% of all breast cancers and less than 1 % of all cancers in men. The mean age at presentation is mainly in sixties. We here present a case of male breast cancer presented at very young age of 29 years, diagnosed on fine needle aspiration which was confirmed later on histopathological examination.

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Core biopsy versus fine needle aspiration cytology (FNAC) for palpable breast cancers. Is image guidance necessary?

European Journal of Cancer ◽

10.1016/s0959-8049(01)80066-6 ◽

2001 ◽

Vol 37 ◽

pp. 12

Author(s):

T. Agarwal ◽

D.A. Cunningham ◽

P. Rajan ◽

D.J. Hadjiminas

Keyword(s):

Fine Needle Aspiration ◽

Fine Needle Aspiration Cytology ◽

Core Biopsy ◽

Image Guidance ◽

Needle Aspiration ◽

Breast Cancers ◽

Aspiration Cytology ◽

Fine Needle ◽

Palpable Breast ◽

Needle Aspiration Cytology

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Diversity of Breast Carcinoma: Histological Subtypes and Clinical Relevance

Clinical Medicine Insights Pathology ◽

10.4137/cpath.s31563 ◽

2015 ◽

Vol 8 ◽

pp. CPath.S31563 ◽

Cited By ~ 72

Author(s):

Jaafar Makki

Keyword(s):

Gene Expression ◽

Breast Carcinoma ◽

Clinical Course ◽

Expression Profiles ◽

Gene Expression Profiles ◽

Molecular Classification ◽

Developed Countries ◽

Breast Cancers ◽

Wide Scope ◽

Histological Subtypes

Mammary carcinoma is the most common malignant tumor in women, and it is the leading cause of mortality, with an incidence of ≥1,000,000 cases occurring worldwide annually. It is one of the most common human neoplasms, accounting for approximately one-quarter of all cancers in females worldwide and 27% of cancers in developed countries with a Western lifestyle. They exhibit a wide scope of morphological features, different immunohistochemical profiles, and unique histopathological subtypes that have specific clinical course and outcome. Breast cancers can be classified into distinct subgroups based on similarities in the gene expression profiles and molecular classification.

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Fine Needle Aspiration Cytology Findings of Breast Lesions in Western Region of Nepal

Journal of Nepalgunj Medical College ◽

10.3126/jngmc.v16i2.24864 ◽

2018 ◽

Vol 16 (2) ◽

pp. 9-12

Author(s):

Pragya Gautam Ghimire ◽

Prasanna Ghimire ◽

Sharmila Gupta

Keyword(s):

Fine Needle Aspiration ◽

Fine Needle Aspiration Cytology ◽

Parasitic Infection ◽

Age Groups ◽

Needle Aspiration ◽

Breast Lesions ◽

Breast Cancers ◽

Aspiration Cytology ◽

Fine Needle ◽

Needle Aspiration Cytology

Aim: Breast cancer is the most common neoplasm worldwide. Fine needle aspiration cytology is a minimally invasive, highly sensitive and cost effective investigation for breast lesions. The aim of our study was to evaluate the spectrum of fine needle aspiration cytology findings of breast lesions. Material and Methods: It was a prospective study conducted in the Department of Pathology during a 2 year period from Jun 2016- May 2018. A total of 284 patients with breast lesions were subjected to ultrasound guided fine needle aspiration cytology. Result: The age of presentation ranged from 13 years to 81 years with a mean age of 34.9±13.5 years. Most common age group for breast lesions was in 21-30 age groups (39.1%). Fibro adenoma was the most common benign pathology (26.8%) followed by fibrocystic changes (26.4%). Malignancy was noted in 16.2% with majority in the 41-50 age groups. Parasitic infection was noted in 2 cases. Conclusion: Screening of breast lesions is warranted resulting in significant reduction of morbidity and mortality related to breast cancers. Fine needle cytology plays a pivotal role in the overall management of breast lesions.

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