scholarly journals Determinants and effects of positive surgical margins after prostatectomy on prostate cancer mortality: a population-based study

BMC Urology ◽  
2014 ◽  
Vol 14 (1) ◽  
Author(s):  
Valesca P Retèl ◽  
Christine Bouchardy ◽  
Massimo Usel ◽  
Isabelle Neyroud-Caspar ◽  
Franz Schmidlin ◽  
...  
The Prostate ◽  
2017 ◽  
Vol 77 (8) ◽  
pp. 859-865 ◽  
Author(s):  
Thorstein Saeter ◽  
Ljiljana Vlatkovic ◽  
Gudmund Waaler ◽  
Einar Servoll ◽  
Jahn M. Nesland ◽  
...  

Oncotarget ◽  
2017 ◽  
Vol 8 (41) ◽  
pp. 69709-69721 ◽  
Author(s):  
Felix M. Chinea ◽  
Vivek N. Patel ◽  
Deukwoo Kwon ◽  
Narottam Lamichhane ◽  
Chris Lopez ◽  
...  

2005 ◽  
Vol 173 (4S) ◽  
pp. 146-146
Author(s):  
Eric J. Bergstralh ◽  
Rosebud O. Roberts ◽  
Michael M. Lieber ◽  
Sara A. Farmer ◽  
Jeffrey M. Slezak ◽  
...  

1999 ◽  
Vol 161 (1) ◽  
pp. 353-353 ◽  
Author(s):  
S.J. Jacobsen ◽  
E.J. Bergstralh ◽  
S.K. Katusic ◽  
H.A. Guess ◽  
C.H. Darby ◽  
...  

Urology ◽  
2007 ◽  
Vol 70 (5) ◽  
pp. 936-941 ◽  
Author(s):  
Eric J. Bergstralh ◽  
Rosebud O. Roberts ◽  
Sara A. Farmer ◽  
Jeffrey M. Slezak ◽  
Michael M. Lieber ◽  
...  

2014 ◽  
Vol 30 (11) ◽  
pp. 2451-2458 ◽  
Author(s):  
Javier Jerez-Roig ◽  
Dyego L. B. Souza ◽  
Pablo F. M. Medeiros ◽  
Isabelle R. Barbosa ◽  
Maria P. Curado ◽  
...  

Prostate cancer mortality projections at the nationwide and regional levels to the year 2025 are carried out in this ecological study that is based on an analysis of Brazilian trends between 1996 and 2010. The predictions were made for the period 2011-2025 utilizing the Nordpred program based on the period of 1996-2010, using the age-period-cohort model. A significant increase was observed in the Brazilian rates between 1996 and 2006, followed by a non-significant decrease. The projections indicate a decrease in rates at a national level as well as for the Central, South and Southeast regions. Increases are expected for the North and Northeast regions. In conclusion, a reduction in the mortality rates for prostate cancer in Brazil is expected to the year 2025, as well as for the Central, South and Southeast regions. However, an increase in the absolute number of deaths in all regions is expected due to the anticipated aging of the population.


2006 ◽  
Vol 24 (18_suppl) ◽  
pp. 10017-10017
Author(s):  
G. L. Lu-Yao ◽  
P. C. Albertsen ◽  
J. L. Stanford ◽  
T. A. Stukel ◽  
E. S. Walker-Corkery ◽  
...  

10017 Background: It remains unknown whether more intense prostate cancer screening and treatment reduces prostate cancer mortality. We describe the experiences of two population-based cohorts with 15-years follow-up (1987–2001) to address the following questions: 1) does more intense screening and treatment for prostate cancer lead to lower mortality in community settings, and 2) do older men (age ≥75–79) benefit from more intense prostate cancer screening and treatment. Methods: Population-based cohort study consisting of white male Medicare beneficiaries who resided in the regions covered by the Seattle (N=88,863) and Connecticut (N=114,785) cancer registries. Inclusion criteria are age 65–79 and free of prostate cancer on January 1, 1987. All study subjects were followed through death or the end of 2001. The main outcomes are rates of screening for prostate cancer, treatment with radical prostatectomy, external beam radiotherapy, and prostate cancer specific mortality. Results: Between 1987 and 1990, compared to men in Connecticut, men in the Seattle region were 5.4 times (95% C.I. 4.8 - 6.1) more likely to undergo PSA testing, 2.2 times (95% C.I. 1.8 - 2.7) more likely to under go prostate biopsy, 5.9 times (95% C.I. 5.5 - 6.9) more likely to have radial prostatectomy, and 2.3 times (95% C.I. 2.2 - 2.5) more likely to have external beam radiation. The cumulative risk of radical prostatectomy or external beam radiation reached 9.1% in the Seattle cohort and 5.0% in the Connecticut cohort in 2001. After 15 years of follow-up, prostate cancer mortality rates were similar for subjects in the two study regions (hazard ratio of Seattle to CT: 1.01, 95% C.I. 0.93 - 1.09). For older men (aged 75–79 in 1987), however, the prostate cancer mortality rate was slightly higher in the Seattle than the Connecticut cohort (hazard ratio: 1.16, 95% C.I. 1.02 - 1.32). Conclusion: More intense screening for prostate cancer, surgery or radiation among a cohort of Medicare beneficiaries in the Seattle area compared with their counterparts in Connecticut has not lead to significantly lower mortality from prostate cancer over 15 years of follow-up. No significant financial relationships to disclose.


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