Rational design of 13C-labeling experiments for metabolic flux analysis in mammalian cells

BMC Systems Biology ◽

10.1186/1752-0509-6-43 ◽

2012 ◽

Vol 6 (1) ◽

pp. 43 ◽

Author(s):

Scott B Crown ◽

Woo Ahn ◽

Maciek R Antoniewicz

Keyword(s):

Metabolic Flux Analysis ◽

Mammalian Cells ◽

Rational Design ◽

Metabolic Flux ◽

Flux Analysis ◽

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Faculty Opinions recommendation of Evaluation of 13C isotopic tracers for metabolic flux analysis in mammalian cells.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1748956.1271054 ◽

2010 ◽

Author(s):

Hans van Beek

Keyword(s):

Metabolic Flux Analysis ◽

Mammalian Cells ◽

Metabolic Flux ◽

Flux Analysis ◽

Isotopic Tracers

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Gas chromatography–mass spectrometry analysis of 13C labeling in sugars for metabolic flux analysis

Analytical Biochemistry ◽

10.1016/j.ab.2012.03.020 ◽

2012 ◽

Vol 425 (2) ◽

pp. 183-188 ◽

Author(s):

Mohamed Koubaa ◽

Sarra Mghaieth ◽

Brigitte Thomasset ◽

Albrecht Roscher

Keyword(s):

Mass Spectrometry ◽

Gas Chromatography ◽

Metabolic Flux Analysis ◽

Metabolic Flux ◽

Mass Spectrometry Analysis ◽

Gas Chromatography Mass Spectrometry ◽

Flux Analysis ◽

13C Labeling ◽

Spectrometry Analysis ◽

Chromatography Mass Spectrometry

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Effect of lpdA gene knockout on the metabolism in Escherichia coli based on enzyme activities, intracellular metabolite concentrations and metabolic flux analysis by 13C-labeling experiments

Journal of Biotechnology ◽

10.1016/j.jbiotec.2005.09.016 ◽

2006 ◽

Vol 122 (2) ◽

pp. 254-266 ◽

Author(s):

Mai Li ◽

Pei Yee Ho ◽

Shanjing Yao ◽

Kazuyuki Shimizu

Keyword(s):

Escherichia Coli ◽

Metabolic Flux Analysis ◽

Enzyme Activities ◽

Metabolic Flux ◽

Gene Knockout ◽

Flux Analysis ◽

Intracellular Metabolite ◽

13C Labeling ◽

Metabolite Concentrations

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Metabolic Flux Analysis of Mammalian Cells

Cell Engineering - Systems Biology ◽

10.1007/1-4020-5252-9_9 ◽

2007 ◽

pp. 275-299 ◽

Author(s):

D.E. Martens

Keyword(s):

Metabolic Flux Analysis ◽

Mammalian Cells ◽

Metabolic Flux ◽

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Production process monitoring by serial mapping of microbial carbon flux distributions using a novel Sensor Reactor approach: II—13C-labeling-based metabolic flux analysis and l-lysine production

Metabolic Engineering ◽

10.1016/s1096-7176(03)00005-3 ◽

2003 ◽

Vol 5 (2) ◽

pp. 96-107 ◽

Author(s):

A. Drysch ◽

M. El Massaoudi ◽

C. Mack ◽

R. Takors ◽

A.A. de Graaf ◽

...

Keyword(s):

Production Process ◽

Process Monitoring ◽

Metabolic Flux Analysis ◽

Carbon Flux ◽

Metabolic Flux ◽

Flux Analysis ◽

Lysine Production ◽

13C Labeling ◽

Microbial Carbon

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Metabolic Flux Analysis in Systems Biology of Mammalian Cells

Genomics and Systems Biology of Mammalian Cell Culture ◽

10.1007/10_2011_99 ◽

2011 ◽

pp. 109-132 ◽

Author(s):

Jens Niklas ◽

Elmar Heinzle

Keyword(s):

Systems Biology ◽

Metabolic Flux Analysis ◽

Mammalian Cells ◽

Metabolic Flux ◽

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Metabolic flux analysis of yfiD gene knockout Escherichia coli based on 13C-labeling experiments under anaerobic conditions

Journal of Biotechnology ◽

10.1016/j.jbiotec.2008.07.066 ◽

2008 ◽

Vol 136 ◽

pp. S34 ◽

Author(s):

Zihe Liu ◽

Qingzhao Wang ◽

Xueming Zhao

Keyword(s):

Escherichia Coli ◽

Metabolic Flux Analysis ◽

Metabolic Flux ◽

Gene Knockout ◽

Flux Analysis ◽

Anaerobic Conditions ◽

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13C labeling analysis of sugars by high resolution-mass spectrometry for metabolic flux analysis

Analytical Biochemistry ◽

10.1016/j.ab.2017.02.005 ◽

2017 ◽

Vol 527 ◽

pp. 45-48 ◽

Author(s):

Sébastien Acket ◽

Anthony Degournay ◽

Franck Merlier ◽

Brigitte Thomasset

Keyword(s):

Mass Spectrometry ◽

High Resolution ◽

Metabolic Flux Analysis ◽

Metabolic Flux ◽

High Resolution Mass Spectrometry ◽

Flux Analysis ◽

13C Labeling ◽

High Resolution Mass ◽

Resolution Mass

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Metabolic Flux Analysis of Mammalian Cells in High Cell Density Perfusion Cultures Targetting Real-Time Application

IFAC Proceedings Volumes ◽

10.1016/s1474-6670(17)34209-x ◽

2001 ◽

Vol 34 (5) ◽

pp. 137-142

Author(s):

Richard Biener ◽

Chetan Goudar ◽

Renato Meneses ◽

Maria Ng ◽

Chun Zhang ◽

...

Keyword(s):

Real Time ◽

Cell Density ◽

Metabolic Flux Analysis ◽

Mammalian Cells ◽

Metabolic Flux ◽

High Cell Density ◽

Flux Analysis ◽

High Cell ◽

Perfusion Cultures ◽

Real Time Application

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Metabolic Flux Analysis Based on 13C-Labeling Experiments and Integration of the Information with Gene and Protein Expression Patterns

Recent Progress of Biochemical and Biomedical Engineering in Japan II - Advances in Biochemical Engineering/Biotechnology ◽

10.1007/b94204 ◽

2004 ◽

pp. 1-49 ◽

Author(s):

Kazuyuki Shimizu

Keyword(s):

Protein Expression ◽

Metabolic Flux Analysis ◽

Metabolic Flux ◽

Expression Patterns ◽

Flux Analysis ◽

13C Labeling ◽

Gene And Protein Expression

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