scholarly journals Risk factors associated with birth defects at a tertiary care center in Pakistan

2012 ◽  
Vol 38 (1) ◽  
pp. 68 ◽  
Author(s):  
Mohammad Zeeshan Raza ◽  
Asfandyar Sheikh ◽  
Syed Salman Ahmed ◽  
Sajid Ali ◽  
Syed Mumtaz Ali Naqvi
2018 ◽  
Vol 46 (1) ◽  
pp. 525-525
Author(s):  
Sasa Ivanovic ◽  
Lisa Shiels ◽  
Alexander Zywot ◽  
Nirav Mistry ◽  
Kristin Fless ◽  
...  

Author(s):  
Rency M. Jaboi ◽  
Vahitha S. ◽  
Nivedita .

Background: The objective of the study was to identify the socio demographic and clinical factors associated with preeclampsia and eclampsia among primigravida attending a tertiary care center in South India.Methods: A quantitative research approach with case control design was used. Non-probability convenience sampling was used to select two groups of primigravida mothers i.e. one group with 108 mothers having preeclampsia or eclampsia and one group with 108 mothers not having preeclampsia or eclampsia. A structured questionnaire was employed to collect the data.Results: The study found that preeclampsia and eclampsia was significantly associated with maternal age (p=0.026), hemoglobin level (p=0.003), body mass index (p=0.001), weeks of gestation (p=0.016), age at menarche (p=0.003), age at first pregnancy (p=0.007), nutritional education (p=0.001), history of thyroid disorder (p=0.025), family history of hypertension (p=0.016), salt consumption (p=0.001), consumption of fried fatty food (p=0.008) and processed sugar (p=0.045), and intake of green leafy vegetables (p=0.001), pulses and beans(p=0.031) and activity (p=0.015). In the multiple regression analysis, body mass index (Adjusted Odds Ratio [OR] 2.28 [1.40-3.71] p=0.001), thyroid disorder (adjusted OR 2.756 [1.135-6.645] p=0.025) and intake of green leafy vegetables (adjusted OR 1.69 [1.223-2.360] p=0.002) were found to be independent risk factors associated with preeclampsia and eclampsia.Conclusion: The study concluded that the risk factors should be identified and evaluated during the antenatal visits for early detection so as to reduce maternal and neonatal mortality. 


2019 ◽  
Vol 12 (2) ◽  
pp. 31-35
Author(s):  
Padma Chandavathu ◽  
◽  
Akurathi Krishna Rao ◽  

2015 ◽  
Vol 16 (4) ◽  
pp. 231-236 ◽  
Author(s):  
Cuneyt Eftal Taner ◽  
Atalay Ekin ◽  
Ulas Solmaz ◽  
Cenk Gezer ◽  
Birgul Cetin ◽  
...  

2021 ◽  
pp. 129-132
Author(s):  
B. Ramkumar ◽  
J. Kannan ◽  
Ingersal. N ◽  
Srigopal mohanty ◽  
Amit saklani ◽  
...  

Context: Gastric cancer(GC) is fth most common cancer worldwide. Mostly presents with advanced stage and poor overall survival. Methods: Retrospective study on clinical, pathological, pattern of distant metastasis(DM) , treatment aspect of GC treated between January 2014 to December 2018 in a tertiary care center in south India. Statistical analysis : Chi square test and multivariate analysis (MVA) were used for analysis. P <0.05 was considered signicant. Results: Median age at diagnosis is 57 years. Higher male : female ratio. Most common presentation was abdominal pain followed vomiting. Malignant Gastric outlet obstruction(MGOO) was present in 22.7%. Histologically , all patients had adenocarcinoma with predominantly moderate differentiation (51.1%). Liver (19.1%)was most common site of metastasis . Curative surgery was done in 35.5% of patients. D2 lymph node dissection was performed in 12.4% of patient. Patients were given perioperative /preoperative/ adjuvant / palliative chemotherapy. MVA revealed history of tobacco use, body of stomach tumor location, nodal disease were risk factors for DM. Conclusion : The present analysis revealed use of tobacco, alcohol intake were main risk factors for GC. Most of the patients present in advanced stage , so prevention by avoiding risk factors and early detection by signs , symptoms and endoscopy are necessary. Use of tobacco,site of tumor location, nodal disease were factors associated with DM. Aggressive management with both surgery and chemotherapy is warranted for locally advanced disease.


2021 ◽  
Vol 41 (3) ◽  
pp. 179-185
Author(s):  
Ibrahim Tawfiq Albabtain ◽  
Abdullah Alkhaldi ◽  
Lama Aldosari ◽  
Lina Alsaadon

BACKGROUND: Pilonidal sinus disease (PSD) is a chronic inflammatory disease of the sacrococcygeal area. Pilonidal sinus recurrence is a matter of concern to both patients and healthcare providers. OBJECTIVES: Estimate the rate of PSD recurrence in our center and identify any risk factors contributing to disease recurrence. DESIGN: Retrospective. SETTING: Tertiary care center in Riyadh. PATIENTS AND METHODS: All patients who underwent surgery for primary or recurrent pilonidal sinus between 1 January 2016 to 30 June 2019 were included to allow for at least 1-year of follow-up at the time of data collection. MAIN OUTCOME MEASURE: Recurrence rate of PSD and risk factors for recurrence. SAMPLE SIZE AND CHARACTERISTICS: 369 patients: 329 males (89.2%) and 40 (10.8%) females. Median (interquartile range) age was 21 (18-26) years. RESULTS: Of the 369 included patients, recurrence was identified in 84 (22.8%) cases [95% confidence interval (CI) 18.6-27.4], and the mean timing of recurrence was 1.8 (1.6) years after the primary surgery. In a multivariate logistic regression analysis, increased age and post-operative seroma fluid discharge were independent risk factors for recurrence. In contrast, preoperative antibiotic prophylaxis and postoperative hair removal were effective in reducing recurrence. Type of surgery closure had no effect on recurrence, yet primary closure was associated with early onset of recurrence compared to secondary closure ( P =.02). CONCLUSION: Our findings on the factors associated with recurrence of PSD are consistent with many reports in the literature. Reported prevalence estimates vary widely. LIMITATION: Single center, small sample size, retrospective. CONFLICT OF INTEREST: None.


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