Chondroitin sulfate proteoglycan 4 specific chimeric antigen receptor therapy for pediatric solid tumors

Journal for ImmunoTherapy of Cancer ◽

10.1186/2051-1426-2-s3-p39 ◽

2014 ◽

Vol 2 (S3) ◽

Author(s):

Nicholas Tschernia ◽

Rimas Orentas ◽

Crystal Mackall

Keyword(s):

Chondroitin Sulfate ◽

Solid Tumors ◽

Chimeric Antigen Receptor ◽

Antigen Receptor ◽

Chondroitin Sulfate Proteoglycan ◽

Sulfate Proteoglycan ◽

Pediatric Solid Tumors ◽

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Chondroitin sulfate proteoglycan 4 as a target for chimeric antigen receptor-based T-cell immunotherapy of solid tumors

Expert Opinion on Therapeutic Targets ◽

10.1517/14728222.2015.1068759 ◽

2015 ◽

Vol 19 (10) ◽

pp. 1339-1350 ◽

Author(s):

Yangyang Wang ◽

Claudia Geldres ◽

Soldano Ferrone ◽

Gianpietro Dotti

Keyword(s):

T Cell ◽

Chondroitin Sulfate ◽

Solid Tumors ◽

Chimeric Antigen Receptor ◽

Antigen Receptor ◽

Chondroitin Sulfate Proteoglycan ◽

Sulfate Proteoglycan ◽

Cell Immunotherapy ◽

Proteoglycan 4 ◽

T Cell Immunotherapy

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Abstract 3151: T cells engineered to express a chimeric antigen receptor targeting chondroitin sulfate proteoglycan 4 (CSPG4) specifically kill medulloblastoma and produce inflammatory cytokines

10.1158/1538-7445.am2015-3151 ◽

2015 ◽

Author(s):

Christopher M. Rota ◽

Nicholas Tschernia ◽

Steven Feldman ◽

Crystal Mackall ◽

Daniel W. Lee

Keyword(s):

T Cells ◽

Chondroitin Sulfate ◽

Inflammatory Cytokines ◽

Chimeric Antigen Receptor ◽

Antigen Receptor ◽

Chondroitin Sulfate Proteoglycan ◽

Sulfate Proteoglycan ◽

Receptor Targeting ◽

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T Lymphocytes Redirected against the Chondroitin Sulfate Proteoglycan-4 Control the Growth of Multiple Solid Tumors both In Vitro and In Vivo

Clinical Cancer Research ◽

10.1158/1078-0432.ccr-13-2218 ◽

2013 ◽

Vol 20 (4) ◽

pp. 962-971 ◽

Author(s):

Claudia Geldres ◽

Barbara Savoldo ◽

Valentina Hoyos ◽

Ignazio Caruana ◽

Ming Zhang ◽

...

Keyword(s):

T Lymphocytes ◽

Chondroitin Sulfate ◽

Solid Tumors ◽

Chondroitin Sulfate Proteoglycan ◽

Sulfate Proteoglycan ◽

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Faculty Opinions recommendation of T lymphocytes redirected against the chondroitin sulfate proteoglycan-4 control the growth of multiple solid tumors both in vitro and in vivo.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.718207741.793517244 ◽

2016 ◽

Author(s):

Bruce Brockstein

Keyword(s):

T Lymphocytes ◽

Chondroitin Sulfate ◽

Solid Tumors ◽

Chondroitin Sulfate Proteoglycan ◽

Sulfate Proteoglycan ◽

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Chondroitin Sulfate Proteoglycan 4 and Its Potential As an Antibody Immunotherapy Target across Different Tumor Types

Frontiers in Immunology ◽

10.3389/fimmu.2017.01911 ◽

2018 ◽

Vol 8 ◽

Author(s):

Kristina M. Ilieva ◽

Anthony Cheung ◽

Silvia Mele ◽

Giulia Chiaruttini ◽

Silvia Crescioli ◽

...

Keyword(s):

Chondroitin Sulfate ◽

Chondroitin Sulfate Proteoglycan ◽

Sulfate Proteoglycan ◽

Proteoglycan 4 ◽

Antibody Immunotherapy ◽

Immunotherapy Target ◽

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Abca8b promotes myelination via regulation of chondroitin sulfate proteoglycan 4 localization in oligodendrocyte precursor cells in mice

The Journal of Lipid Research ◽

10.1016/j.jlr.2021.100147 ◽

2021 ◽

pp. 100147

Author(s):

Yiran Liu ◽

David Castano ◽

Francesco Girolamo ◽

Laia Trigueros-Motos ◽

Han-Gyu Bae ◽

...

Keyword(s):

Chondroitin Sulfate ◽

Precursor Cells ◽

Chondroitin Sulfate Proteoglycan ◽

Oligodendrocyte Precursor Cells ◽

Sulfate Proteoglycan ◽

Proteoglycan 4 ◽

Oligodendrocyte Precursor

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212Pb-Labeled Antibody 225.28 Targeted to Chondroitin Sulfate Proteoglycan 4 for Triple-Negative Breast Cancer Therapy in Mouse Models

International Journal of Molecular Sciences ◽

10.3390/ijms19040925 ◽

2018 ◽

Vol 19 (4) ◽

pp. 925 ◽

Author(s):

Benjamin Kasten ◽

Patsy Oliver ◽

Harrison Kim ◽

Jinda Fan ◽

Soldano Ferrone ◽

...

Keyword(s):

Breast Cancer ◽

Cancer Therapy ◽

Chondroitin Sulfate ◽

Mouse Models ◽

Triple Negative Breast Cancer ◽

Triple Negative ◽

Chondroitin Sulfate Proteoglycan ◽

Sulfate Proteoglycan ◽

Breast Cancer Therapy ◽

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Roles of chondroitin sulfate proteoglycan 4 in fibrogenic/adipogenic differentiation in skeletal muscle tissues

Experimental Cell Research ◽

10.1016/j.yexcr.2016.08.023 ◽

2016 ◽

Vol 347 (2) ◽

pp. 367-377 ◽

Author(s):

Shiho Takeuchi ◽

Shin-Ichi Nakano ◽

Katsuyuki Nakamura ◽

Atsufumi Ozoe ◽

Peggie Chien ◽

...

Keyword(s):

Skeletal Muscle ◽

Chondroitin Sulfate ◽

Adipogenic Differentiation ◽

Chondroitin Sulfate Proteoglycan ◽

Sulfate Proteoglycan ◽

Muscle Tissues ◽

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Mass Spectrometric Identification of Collagen Alpha-1 (III) Chain and Chondroitin Sulfate Proteoglycan-4 Nitration in Patients with Acute Pulmonary Embolism: A Preliminary Study

Free Radical Biology and Medicine ◽

10.1016/j.freeradbiomed.2017.04.124 ◽

2017 ◽

Vol 108 ◽

pp. S30

Author(s):

Mutay Aslan ◽

Filiz Ozcan ◽

Zeynep Avcil ◽

Oktay H. Ozturk ◽

Cenker Eken

Keyword(s):

Pulmonary Embolism ◽

Chondroitin Sulfate ◽

Acute Pulmonary Embolism ◽

Mass Spectrometric ◽

Chondroitin Sulfate Proteoglycan ◽

Sulfate Proteoglycan ◽

Spectrometric Identification ◽

Proteoglycan 4 ◽

Mass Spectrometric Identification ◽

Preliminary Study

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A chondroitin sulfate proteoglycan 4‑specific monoclonal antibody inhibits melanoma cell invasion in a spheroid model

International Journal of Oncology ◽

10.3892/ijo.2021.5250 ◽

2021 ◽

Vol 59 (3) ◽

Author(s):

Karolina Uranowska ◽

Mahzeiar Samadaei ◽

Tanja Kalic ◽

Matthias Pinter ◽

Heimo Breiteneder ◽

...

Keyword(s):

Monoclonal Antibody ◽

Chondroitin Sulfate ◽

Melanoma Cell ◽

Cell Invasion ◽

Chondroitin Sulfate Proteoglycan ◽

Sulfate Proteoglycan ◽

Specific Monoclonal Antibody ◽

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