scholarly journals Suppression of the NF-κB cofactor Bcl3 inhibits mammary epithelial cell apoptosis and, in breast tumours, correlates with poor prognosis

2008 ◽  
Vol 10 (S2) ◽  
Author(s):  
A Wakefield ◽  
L Piggott ◽  
D Croston ◽  
WG Jiang ◽  
R Clarkson
Keyword(s):  
Epithelial Cell ◽  
Cell Apoptosis ◽  
Mammary Epithelial Cell ◽  
Poor Prognosis ◽  
Mammary Epithelial ◽  
Breast Tumours ◽  
Epithelial Cell Apoptosis

miR-224 Affects Mammary Epithelial Cell Apoptosis and Triglyceride Production by Downregulating ACADM and ALDH2 Genes

2017 ◽  
Vol 36 (1) ◽  
pp. 26-33 ◽  
Author(s):  
Binglei Shen ◽  
Qiqi Pan ◽  
Yuwei Yang ◽  
Yan Gao ◽  
Xin Liu ◽  
...  
Keyword(s):  
Epithelial Cell ◽  
Cell Apoptosis ◽  
Mammary Epithelial Cell ◽  
Mammary Epithelial ◽  
Epithelial Cell Apoptosis

scholarly journals The Signaling Mechanism of TGF-β1 Induced Bovine Mammary Epithelial Cell Apoptosis

2012 ◽  
Vol 25 (3) ◽  
pp. 304-310 ◽  
Author(s):  
He-Shuang Di ◽  
Li-Gang Wang ◽  
Gen-Lin Wang ◽  
Lei Zhou ◽  
Yuan-Yuan Yang
Keyword(s):  
Epithelial Cell ◽  
Cell Apoptosis ◽  
Mammary Epithelial Cell ◽  
Mammary Epithelial ◽  
Signaling Mechanism ◽  
Bovine Mammary Epithelial Cell ◽  
Epithelial Cell Apoptosis ◽  
Tgf Β1

Abstract 4774: Epimorphin inhibits mammary epithelial cell apoptosis through induction of IKBKE

2011 ◽  
Author(s):  
Davitte Khauv ◽  
Magdalena Cichon ◽  
Derek Radisky
Keyword(s):  
Epithelial Cell ◽  
Cell Apoptosis ◽  
Mammary Epithelial Cell ◽  
Mammary Epithelial ◽  
Epithelial Cell Apoptosis

scholarly journals EGF-Induced miR-223 Modulates Goat Mammary Epithelial Cell Apoptosis and Inflammation via ISG15

2021 ◽  
Vol 9 ◽  
Author(s):  
Yue Zhang ◽  
Qiong Wu ◽  
Guanglin Niu ◽  
Jidan Liu ◽  
Fangjun Cao ◽  
...  
Keyword(s):  
Mammary Gland ◽  
Epithelial Cell ◽  
Mammary Epithelial Cell ◽  
Caspase 3 ◽  
Mammary Epithelial ◽  
Protein Expressions ◽  
Epithelial Cell Apoptosis ◽  
Epidermal Growth ◽  
Apoptosis And Inflammation ◽  
Anti Inflammation

The health of mammary gland is essential for lactation. Epidermal growth factor (EGF) is reported to play an important role in lactation initiation and miR-223 is a conserved microRNA in anti-inflammation. In this study, EGF was found to induce a higher expression of miR-223 in goat mammary epithelial cell (gMEC). The downstream genes of miR-223 were screened by RNA sequencing, including Interferon-stimulated gene product 15 (ISG15), a pivotal immune responder, which was detected to be downregulated by EGF and miR-223. Due to the correlation between inflammation and apoptosis, the gMEC apoptosis modulated by EGF, miR-223, and ISG15 was investigated, and the protein expressions of Bcl-2/Bax, Caspase 3 and p53 were examined to evaluate the apoptosis of gMEC. The protein expressions of p-STAT3/STAT3, PR, FOXC1, and HOXA10, which had been shown to be related to inflammation, were detected to assess the inflammation of gMEC. This study provided a regulation axis, EGF/miR-223/ISG15, and illustrated its regulation to gMEC apoptosis and inflammation.

PRRX2 as a novel TGF-β-induced factor enhances invasion and migration in mammary epithelial cell and correlates with poor prognosis in breast cancer

2016 ◽  
Vol 55 (12) ◽  
pp. 2247-2259 ◽  
Author(s):  
Yu-Lin Juang ◽  
Yung-Ming Jeng ◽  
Chi-Long Chen ◽  
Huang-Chun Lien
Keyword(s):  
Breast Cancer ◽  
Epithelial Cell ◽  
Mammary Epithelial Cell ◽  
Poor Prognosis ◽  
Mammary Epithelial ◽  
Invasion And Migration ◽  
And Migration

Role of p53 Mammary Epithelial Cell Senescence

2005 ◽  
Author(s):  
Goberdhan P. Dimri
Keyword(s):  
Epithelial Cell ◽  
Mammary Epithelial Cell ◽  
Cell Senescence ◽  
Mammary Epithelial
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