scholarly journals PB.39: Minimising the impact of breast screening extension: a 1-year experience of a South West breast screening unit

2013 ◽  
Vol 15 (S1) ◽  
Author(s):  
K Giles ◽  
R Currie
Keyword(s):  
Breast Screening ◽  
South West ◽  
Screening Unit ◽  
The Impact

Interval Breast Cancers in the NHS Breast Screening Programme: Does the Current Definition Exclude Too Many?

1997 ◽  
Vol 4 (3) ◽  
pp. 169-173 ◽  
Author(s):  
A M Faux ◽  
D C Richardson ◽  
G M Lawrence ◽  
M E Wheaton ◽  
M G Wallisconsultant
Keyword(s):  
Breast Screening ◽  
Interval Cancer ◽  
Breast Cancers ◽  
Interval Cancers ◽  
Exclusion Criteria ◽  
National Statistics ◽  
Screening Unit ◽  
Cancer Rates ◽  
Definition Of ◽  
The Impact

Objectives— To examine the impact of the definition of interval breast cancers on interval cancer rates arising from the prevalent (first) screening round. Design— Interval breast cancers arising from the prevalent (first) screening round at the Warwickshire, Solihull and Coventry Breast Screening Unit (17 April 1989 to 31 March 1992) were identified by comparison of data held at the unit with records at the West Midlands Cancer Intelligence Unit. Exclusion criteria used in National statistics were applied to this sample to quantify their impact on achieved interval cancer rates. The round lengths experienced by individual women at the unit were determined from the prevalent and incident invitation dates for 155 women with incident (re-screen) breast cancers detected in the second round. Setting— Warwickshire, Solihull and Coventry Breast Screening Unit. Subects—59 017 women screened between 17 April 1989 and 31 March 1992 with a negative screening result and 155 women with incident screen detected cancers. Results— A total of 278 interval cancers were identified, giving an overall rate from the prevalent screening round of 47.1/10 000 women screened. Of these, 213 met the criteria used in the definition of interval cancers for National statistics and were termed “core” interval cancers. The overall “core” interval rate was 36.1/10 000 women screened, similar to interval cancer rates found in the north west of United Kingdom. Thus applying commonly used exclusion criteria produced a 23.4% reduction in the apparent interval cancer rate, with the largest decrease resulting from the exclusion of cancers arising at 36 months or more from the last screen. Conclusions— The exclusion criteria used in the definition of interval cancers have a significant impact on observed interval cancer rates. Of particular concern is the exclusion in the current National definitions of cancers arising at 36 months or more from the last screen, which may mask a problem with significant implications for the success of the NHSBSP.

scholarly journals Trends in incidence of pneumococcal disease before introduction of conjugate vaccine: South West England, 1996–2005

2007 ◽  
Vol 136 (8) ◽  
pp. 1096-1102 ◽  
Author(s):  
C. A. IHEKWEAZU ◽  
D. A. B. DANCE ◽  
R. PEBODY ◽  
R. C. GEORGE ◽  
M. D. SMITH ◽  
...  
Keyword(s):  
Blood Culture ◽  
Pneumococcal Disease ◽  
Annual Incidence ◽  
Protection Agency ◽  
South West ◽  
The Mean ◽  
The Impact ◽  
Susceptibility And Resistance ◽  
South West England ◽  
Immunization Programmes

SUMMARYIntroduction of pneumococcal conjugate and polysaccharide vaccines into the United Kingdom's routine immunization programmes is expected to change the epidemiology of invasive pneumococcal disease (IPD). We have documented the epidemiology of IPD in an English region (South West) with high-quality surveillance data before these programmes were established. We analysed data on isolates of Streptococcus pneumoniae from blood and CSF between 1996 and 2005 from microbiology laboratories in the South West that were reported and/or referred for serotyping to the Health Protection Agency Centre for Infections. The mean annual incidence of IPD increased from 11·2/100 000 in 1996 to 13·6/100 000 in 2005 (P<0·04). After adjusting for annual blood-culture sampling rates in hospitals serving the same catchment populations, an increase in annual incidence of IPD was no longer observed (P=1·0). Variation in overall incidence between laboratories could also be explained by variation in blood culture rates. The proportion of disease caused by serotypes 6B, 9V and 14 decreased significantly (P=0·001, P=0·007, and P=0·027 respectively) whereas that caused by serotype 4, 7F and 1 increased (P=0·001, P=0·003, and P<0·001 respectively) between 2000 and 2005. The level of penicillin non-susceptibility and resistance to erythromycin remained stable (2% and 12% respectively). This study provides an important baseline to assess the impact of changing vaccination programmes on the epidemiology of IPD, thus informing future use of pneumococcal vaccines.

Cumulative reproductive performance effect on overall lifetime productivity in Merino sheep

2018 ◽  
Vol 58 (8) ◽  
pp. 1470
Author(s):  
J. S. Richards ◽  
M. A. Sladek ◽  
G. J. Lee
Keyword(s):  
Reproductive Performance ◽  
New South ◽  
Dental Health ◽  
Age Groups ◽  
The South ◽  
Performance Effect ◽  
South West ◽  
South Wales ◽  
The Impact ◽  
Effect Of Age

Reproduction is an important driver of profitability in commercial sheep flocks. Historically, Merino flocks have been run with a fixed age structure, ignoring individual merit and casting for age at a specific age. More recently, research has focussed on utilising the variation within age groups by keeping productive older ewes longer and culling less productive ewes earlier. Previous studies have also examined the effect of age on reproduction and the impact of reproduction status on productivity, but little research has been conducted on cumulative effects of reproductive performance on later productivity, reproduction and health. The present study examined the impact of higher lifetime reproduction on other key production and fitness traits in older ewes run under commercial conditions. Data were collected from two commercial wool-producing properties in the South West Slopes and the Central West Plains of New South Wales during 2009–2011. Reproduction, fleece measurements, bodyweight and condition and dental health were recorded during the study. The results showed that age had a bigger effect on productivity and dental health than did cumulative lifetime reproduction. Environment and genetics determined the level of impact, with minimal loss in productivity from increased age of animals occurring in the South West Slopes flock, whereas the Central West Plains flock would appear to require closer monitoring of productivity as ewes aged. The data collected did not allow separation of the genetic and environmental influences within the study. Retaining animals with a higher reproductive performance past normal culling age does not necessarily result in reduction of productivity or ewe health, but this must be monitored.

scholarly journals Using Record Linkage to Examine the Impact of Poor Mental Health on Breast Screening Uptake

2018 ◽  
Vol 3 (2) ◽  
Author(s):  
Emma Ross ◽  
Dermot O'Reilly
Keyword(s):  
Mental Health ◽  
Breast Screening ◽  
Census Data ◽  
Breast Cancer Mortality ◽  
Poor Mental Health ◽  
Breast Screening Programme ◽  
Screening Uptake ◽  
National Breast ◽  
The Impact ◽  
Prescribing Information

BackgroundThe UK National Breast Screening Programme is estimated to reduce breast cancer mortality by 20%. To maximise the benefits of the programme, we first need to understand the underlying factors contributing to variations in screening uptake. One potentially significant factor which may contribute to these gradients in screening uptake is poor mental health. ObjectivesThe objectives of this study were to examine the impact of poor mental health on breast screening uptake, and whether this explained any of the previously observed socio-demographic gradients in screening uptake. MethodsBreast screening records were obtained from the National Breast Screening System (NBSS) and were subsequently linked to 2011 Census data within the Northern Ireland Longitudinal Study (NILS). The NILS encompasses 28\% of Census data. This was then linked to psychotropic prescribing information from the Enhanced Prescribing Database (EPD), to produce a de-identified research dataset containing 57,328 women. FindingsWomen with self-reported poor mental health were over 20% less likely to attend screening compared to their counterparts who didn't have poor mental health. Using psychotropic prescribing information as a proxy for the presence of mental illness yielded similar results, with those taking anxiolytics, antipsychotics or hypnotics in the three months before screening invitation significantly less likely to attend than those who were not. ConclusionWomen with poor mental health were significantly less likely to attend breast screening. However, poor mental health did not explain any of the previously determined socio-demographic gradients in screening uptake.

scholarly journals Risk of Plasmodium falciparum infection in south-west Burkina Faso - potential impact of expanding eligibility for seasonal malaria chemoprevention

2021 ◽  
Author(s):  
Anne L Wilson ◽  
Steve W Lindsay ◽  
Alfred Tiono ◽  
Jean Baptiste Yaro ◽  
Hilary Ranson ◽  
...  
Keyword(s):  
Risk Factors ◽  
Plasmodium Falciparum ◽  
Burkina Faso ◽  
Malaria Transmission ◽  
Malaria Control ◽  
Control Measures ◽  
Sub Saharan Africa ◽  
South West ◽  
Seasonal Malaria Chemoprevention ◽  
The Impact

Abstract Background Burkina Faso has one of the highest malaria burdens in sub-Saharan Africa despite the mass deployment of insecticide-treated nets (ITNs) and use of seasonal malaria chemoprevention (SMC) in children aged up to 5 years. Identification of risk factors for Plasmodium falciparum infection in rural Burkina Faso could help to identify and target malaria control measures. Methods A cross-sectional survey of 1,199 children and adults was conducted during the peak malaria transmission season in south-west Burkina Faso in 2017. Logistic regression was used to identify risk factors for microscopically confirmed P. falciparum infection. A malaria transmission dynamic model was used to determine the impact on malaria cases averted of administering SMC to children aged 5–15 year old. Results P. falciparum prevalence was 32.8% in the study population. Children aged 5 to < 10 years old were at 3.74 times the odds (95% CI = 2.68–5.22, p < 0.001) and children aged 10 to 15 years old at 3.14 times the odds (95% CI = 1.20–8.21, p = 0.02) of P. falciparum infection compared to children aged less than 5 years old. Administration of SMC to children aged up to 10 years is predicted to avert an additional 57 malaria cases per 1000 population per year (9.4% reduction) and administration to children aged up to 15 years would avert an additional 89 malaria cases per 1000 population per year (14.6% reduction) in the Cascades Region, assuming coverage of pyrethroid-piperonyl butoxide ITNs. Conclusion Malaria infections were high in all age strata, although highest in children aged 5 to 15 years, despite roll out of core malaria control interventions. Given the burden of infection in school-age children, extension of the eligibility criteria for SMC could help reduce the burden of malaria in Burkina Faso and other countries in the region.

scholarly journals The fast-track outpatient clinic significantly decreases hospitalisation rates among polymyalgia rheumatica patients

2021 ◽  
Vol 5 (1) ◽  
Author(s):  
Stavros Chrysidis ◽  
Philip Rask Lage-Hansen ◽  
Nikoletta Svendsen ◽  
Andreas P. Diamantopoulos
Keyword(s):  
Polymyalgia Rheumatica ◽  
Fast Track ◽  
Clinical Symptoms ◽  
Classification Criteria ◽  
Duration Of Symptoms ◽  
Prednisolone Dose ◽  
South West ◽  
Hospitalised Patients ◽  
Number Of Patients ◽  
The Impact

Abstract Objectives This study aimed to investigate the hospitalisation rates and the reasons for hospitalisation in patients with polymyalgia rheumatica (PMR). Furthermore, it aimed to clarify the impact of a newly established Fast Track Clinic (FTC) approach on hospitalisation rates in connection with PMR diagnosis. Methods Patients diagnosed with PMR at South-West Jutland Hospital, Denmark, between 2013 and 2018 were included retrospectively. Only patients fulfilling the 2012 EULAR/ACR classification criteria were included in our cohort. An FTC for patients suspected of having PMR was established in the rheumatologic department of South-West Jutland Hospital in January 2018. Results Over 6 years (2013 to 2017), 254 patients were diagnosed with PMR, 56 of them while hospitalised. Hospitalised patients were more likely to have a higher initial CRP mean ± standard deviation (SD) 99.53 ± 59.36 vs 45.82 ± 36.96 mg/lt (p <  0.0001) and a shorter duration of symptoms (p = 0.0018). After implementing the FTC, a significant decrease in hospitalisation rates (from 20.4% to 3,5%) and inpatient days of care (mean ± SD 4.15 ± 3.1 vs 1 ± 0) were observed. No differences between the two groups were observed regarding clinical symptoms, laboratory values and initial prednisolone dose. Conclusion A substantial number of patients are hospitalised in connection with the PMR diagnosis. The FTC approach can decrease the hospitalisation rates significantly among these patients. Trial registration Retrospectively registered.

Impact of Innovation on the Entrepreneurial Success in Selected Business Enterprises in South-West Nigeria

2017 ◽  
Vol 8 (2) ◽  
pp. 29-38
Author(s):  
Olu Ojo
Keyword(s):  
Product Quality ◽  
Positive Relationship ◽  
Secondary Data ◽  
Corporate Image ◽  
Primary Data ◽  
Manufacturing Companies ◽  
Entrepreneurial Success ◽  
South West ◽  
Business Enterprises ◽  
The Impact

This study examined the impact of innovation on the entrepreneurial success in selected business enterprises in SOUTH-WEST Nigeria. The paper dwelt on the extent to which the selected enterprises innovation effort affects the quality of their product as well as the company image. Five manufacturing companies in the Food and Beverages line were selected using purposive sampling method because of their contributions to economic development of Nigeria while the respondents were selected through stratified random sampling technique. Survey research design was used in carrying out the study. Both primary and secondary data were used in the study. Primary data were collected through the administration of questionnaire while secondary data were garnered from Annual Report and Accounts of the companies. Data were analysed using descriptive and inferential statistics. Hypotheses were tested at 0.05 significant levels with the aid of parametric student t-test. The results revealed that there is a positive relationship between innovation and product quality as well as a positive relationship between innovation and good corporate image and that both of them significantly affect entrepreneurial success. The study recommends that business enterprises should engage more on innovation of their production process to improve their product quality and even enhances good corporate image. This will help them to sustain their position in the face of stiff competition.

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