scholarly journals Collapsibility of jugular veins, subclavian veins and inferior vena cava as predictors of fluid responsiveness in patients on pressure support ventilation: a prospective cohort study

Critical Care ◽  
2015 ◽  
Vol 19 (Suppl 1) ◽  
pp. P184
Author(s):  
Y Iizuka ◽  
M Sanui ◽  
T Nomura
Keyword(s):  
Cohort Study ◽  
Inferior Vena Cava ◽  
Fluid Responsiveness ◽  
Prospective Cohort Study ◽  
Pressure Support Ventilation ◽  
Prospective Cohort ◽  
Pressure Support ◽  
Inferior Vena ◽  
Vena Cava ◽  
Jugular Veins

scholarly journals Non-invasive assessment of fluid responsiveness to guide fluid therapy in patients with sepsis in the emergency department: a prospective cohort study

2021 ◽  
pp. emermed-2020-209771
Author(s):  
Nienke K Koopmans ◽  
Renate Stolmeijer ◽  
Ben C Sijtsma ◽  
Paul A van Beest ◽  
Christiaan E Boerma ◽  
...  
Keyword(s):  
Cohort Study ◽  
Fluid Responsiveness ◽  
Prospective Cohort Study ◽  
Fluid Therapy ◽  
Prospective Cohort ◽  
Fluid Challenge ◽  
Fluid Bolus ◽  
Non Invasive ◽  
Similar Patient ◽  
Passive Leg Raise

BackgroundLittle is known about optimal fluid therapy for patients with sepsis without shock who present to the ED. In this study, we aimed to quantify the effect of a fluid challenge on non-invasively measured Cardiac Index (CI) in patients presenting with sepsis without shock.MethodsIn a prospective cohort study, CI, stroke volume (SV) and systemic vascular resistance (SVR) were measured non-invasively in 30 patients presenting with sepsis without shock to the ED of a large teaching hospital in the Netherlands between May 2018 and March 2019 using the ClearSight system. After baseline measurements were performed, a passive leg raise (PLR) was done to simulate a fluid bolus. Measurements were then repeated 30, 60, 90 and 120 s after PLR. Finally, a standardised 500 mL NaCl 0.9% intravenous bolus was administered after which final measurements were done. Fluid responsiveness was defined as >15% increase in CI after a standardised fluid challenge.Measurements and main resultsSeven out of 30 (23%) patients demonstrated a >15% increase in CI after PLR and after a 500 mL fluid bolus. Fluid responders had a higher estimated glomerular filtration rate (eGFR) (64 (44–78) vs 37 (23–47), p=0.009) but otherwise similar patient and treatment characteristics as non-responders. Baseline measurements of cardiac output (CO), CI, SV and SVR were unrelated to PLR fluid responsiveness. The change in CI after PLR was strongly positive correlated to the change in CI after a 500 mL NaCl 0.9% fluid bolus (r=0.88, p<0.001).ConclusionThe results of the present study demonstrate that in patients with sepsis in the absence of shock, three out of four patients do not demonstrate a clinically relevant increase in CI after a standardised fluid challenge. Non-invasive CO monitoring in combination with a PLR test has the potential to identify patients who might benefit from fluid resuscitation and may contribute to a better tailored treatment of these patients.

Accuracy of Ultrasonographic Measurements of Inferior Vena Cava to Determine Fluid Responsiveness: A Systematic Review and Meta-Analysis

2018 ◽  
Vol 35 (4) ◽  
pp. 354-363 ◽  
Author(s):  
Daniele Orso ◽  
Irene Paoli ◽  
Tommaso Piani ◽  
Francesco L. Cilenti ◽  
Lorenzo Cristiani ◽  
...  
Keyword(s):  
Inferior Vena Cava ◽  
Fluid Responsiveness ◽  
Inferior Vena ◽  
Data Extraction ◽  
Meta Analysis ◽  
Vena Cava ◽  
Fluid Challenge ◽  
Area Under The Curve ◽  
Ultrasound Evaluation ◽  
Caval Index

Objective: Fluid responsiveness is the ability to increase the cardiac output in response to a fluid challenge. Only about 50% of patients receiving fluid resuscitation for acute circulatory failure increase their stroke volume, but the other 50% may worsen their outcome. Therefore, predicting fluid responsiveness is needed. In this purpose, in recent years, the assessment of the inferior vena cava (IVC) through ultrasound (US) has become very popular. The aim of our work was to systematically review all the previously published studies assessing the accuracy of the diameter of IVC or its respiratory variations measured through US in predicting fluid responsiveness. Data Sources: We searched in the MEDLINE (PubMed), Embase, Web of Science databases for all relevant articles from inception to September 2017. Study Selection: Included articles specifically addressed the accuracy of IVC diameter or its respiratory variations assessed by US in predicting the fluid responsiveness in critically ill ventilated or not, adult or pediatric patients. Data Extraction: We included 26 studies that investigated the role of the caval index (IVC collapsibility or distensibility) and 5 studies on IVC diameter. Data Synthesis: We conducted a meta-analysis for caval index with 20 studies: The pooled area under the curve, logarithmic diagnostic odds ratio, sensitivity, and specificity were 0.71 (95% confidence interval [CI]: 0.46-0.83), 2.02 (95% CI: 1.29-2.89), 0.71 (95% CI: 0.62-0.80), and 0.75 (95% CI: 0.64-0.85), respectively. Conclusion: An extreme heterogeneity of included studies was highlighted. Ultrasound evaluation of the diameter of the IVC and its respiratory variations does not seem to be a reliable method to predict fluid responsiveness.

116: RESPIRATORY VARIATION OF INFERIOR VENA CAVA DIAMETER IN PATIENTS VENTILATED USING PRESSURE SUPPORT

2018 ◽  
Vol 46 (1) ◽  
pp. 41-41
Author(s):  
Constantin Shuster ◽  
Andrew Hurlburt ◽  
Shaun Ong ◽  
Ken Kaila ◽  
Demetrios Sirounis ◽  
...  
Keyword(s):  
Inferior Vena Cava ◽  
Pressure Support ◽  
Inferior Vena ◽  
Vena Cava ◽  
Respiratory Variation ◽  
Inferior Vena Cava Diameter

Ultrasound Assessment of Inferior Vena Cava Collapsibility Is Not a Valid Measure of Preload Changes During Triggered Positive Pressure Ventilation: A Controlled Cross-Over Study

2011 ◽  
Vol 33 (02) ◽  
pp. 152-159 ◽  
Author(s):  
P. Juhl-Olsen ◽  
C. Frederiksen ◽  
E. Sloth
Keyword(s):  
Inferior Vena Cava ◽  
Pressure Support ◽  
Positive Pressure Ventilation ◽  
Inferior Vena ◽  
Vena Cava ◽  
Positive Pressure ◽  
Vena Cava Inferior ◽  
Valid Measure ◽  
Eine Hohe ◽  
Ultrasound Assessment

Zusammenfassung Ziel: Die respiratorischen Veränderungen im Durchmesser der Vena cava inferior (IVC) wurden durch Messung des Volumenstatus und der Vorlastreagilibität während der Spontanatmung und maschinellen Beatmung bewertet. Allerdings erhalten viele Intensivpatienten eine getriggerte Überdruckbeatmung (PPV). Bei dieser Anwendung gibt es keinen Beweis dafür, dass die „Collapsibility“ der IVC (IVCc) als Ersatz für die Vorlast dient. Unser Ziel war es zu klären, welche Auswirkungen die stufenweise Erhöhung der getriggerten PPV und die unterschiedlichen Vorlast-Bedingungen auf die IVCc haben. Material und Methoden: 10 gesunde Freiwillige wurden an ein Beatmungsgerät mit festsitzender Maske angeschlossen und nach der Basismessung drei verschiedenen Stufen des positiven endexspiratorischen Drucks (PEEP) und der Druckunterstützung (Pressure support, PS) ausgesetzt. Alle Einstellungen des Beatmungsgeräts wurden bei neutraler Vorlast (Horizontalposition), niedriger Vorlast (reverse Trendelenburg-Lage) und hoher Vorlast (Trendelenburg-Lage mit intravenöser Flüssigkeits-Bolusinjektion) durchgeführt. Bei jeder Einstellung des Beatmungsgeräts wurde die IVC während mindestens einem respiratorischen Zyklus durch drei häufig benutzte Ultraschallmethoden dargestellt, darunter der sagittale M-Modus und die 2D-Echokardiografie sowohl in Sagittal- als auch in Transversalansicht. Ergebnisse: Bei ansteigender PS verminderte sich die IVCc (p = 0,01) in der reversen Trendelenburg-Lage, steigender PEEP verursachte eine höhere IVCc in der Trendelenburg-Lage (p = 0,02). In Horizontalposition wurden keine signifikanten Auswirkungen einer steigenden PS, PEEP oder einer Kombination aus beiden beobachtet. Insgesamt zeigte die ANOVA Analyse, dass die IVCc nicht unabhängig von der Vorlast ist. Unter PPV war die IVCc bei neutraler Vorlast mit den meisten Einstellungen des Beatmungsgeräts am höchsten, die IVCc war bei niedriger Vorlast am niedrigsten, während eine hohe Vorlast in der Regel die ICVc zwischen neutraler und hoher Vorlast ermöglichte. Darüber hinaus überschätzte der sagittale M-Mode und die transversale 2D-Echokardiografie die IVCc im Vergleich zur sagittalen 2D-Echokardiografie. Schlussfolgerung: Die erhobenen Ergebnisse dieser Studie zeigen, dass die IVCc nicht als gültiger Parameter für den Vorlaststatus während der PPV angesehen werden kann. Das könnte durch die systematischen Veränderungen der anderen IVCc-Einflussgrößen erklärt werden. Der Vergleich der Methoden ermutigt dazu, die sagittale 2D-Echokardiografie zur dynamischen Darstellung der IVC einzusetzen. Im Vergleich zur sagittalen 2D-Echokardiografie überschätzen der sagittale M-Mode und die transversale 2D-Echokardiografie die IVCc.

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