Subclinical hypothyroidism (SCH), cardiovascular risk and quality of life

2012 ◽  
Author(s):  
Jolanta Weaver
Keyword(s):  
Quality Of Life ◽  
Cardiovascular Risk ◽  
Subclinical Hypothyroidism

scholarly journals To Treat or Not to Treat Subclinical Hypothyroidism, What Is the Evidence?

Medicina ◽  
2020 ◽  
Vol 56 (1) ◽  
pp. 40
Author(s):  
Jan Calissendorff ◽  
Henrik Falhammar
Keyword(s):  
Quality Of Life ◽  
Cardiovascular Risk ◽  
Subclinical Hypothyroidism ◽  
Thyroid Stimulating Hormone ◽  
Term Treatment ◽  
Elderly Subjects ◽  
Subclinical Disease ◽  
Wait And See ◽  
Levothyroxine Treatment

Objective: levothyroxine prescriptions have increased remarkably during the last decade, and it is most likely to be prescribed in subclinical hypothyroidism. The aim of this review was to present data on when levothyroxine treatment should be initiated, and the effects of treatment in subclinical hypothyroidism on symptoms such as weight, quality of life, vitality, cognition, and cardiovascular disease. We also discuss evidence for different thyroid-hormone medications. In addition, the option to withhold medication when there is uncertain diagnosis or lack of clinical improvement is discussed. Methods: a literature search in PubMed on the term “treatment of subclinical hypothyroidism” in combination with “quality of life”, “weight”, “cognition”, and “cerebrovascular disease”. Results: current research supports that levothyroxine should be initiated in patients with a thyroid stimulating hormone (TSH) >10 mIU/L. Treatment for hypothyroidism is becoming more frequent. Symptoms related to vitality, weight, and quality of life in subclinical disease often persist with levothyroxine treatment, and other causes should be explored. Patients with cardiovascular-risk factors may benefit from treatment, especially younger patients. Caution is necessary when treating elderly subjects with levothyroxine. Conclusion: lifelong treatment with levothyroxine should normally only be considered in manifest hypothyroidism. However, in subclinical hypothyroidism with a TSH >10 mIU/L, therapy is indicated. In milder subclinical forms, a wait-and-see strategy is advocated to see if normalization occurs. Subgroups with cardiovascular risk and subclinical hypothyroidism may benefit from levothyroxine therapy.

scholarly journals Influence of a Medium-Impact Exercise Program on Health-Related Quality of Life and Cardiorespiratory Fitness in Females with Subclinical Hypothyroidism: An Open-Label Pilot Study

2013 ◽  
Vol 2013 ◽  
pp. 1-5 ◽  
Author(s):  
Andrea Garces-Arteaga ◽  
Nataly Nieto-Garcia ◽  
Freddy Suarez-Sanchez ◽  
Héctor Reynaldo Triana-Reina ◽  
Robinson Ramírez-Vélez
Keyword(s):  
Quality Of Life ◽  
Cardiorespiratory Fitness ◽  
Subclinical Hypothyroidism ◽  
Exercise Program ◽  
Health Related Quality ◽  
Health Domain ◽  
Related Quality ◽  
Health Related ◽  
Impact Exercise

Objective.To examine the influence of a medium-impact exercise program (MIEP) on health-related quality of life (HRQoL) and cardiorespiratory fitness (VO2max) in females with subclinical hypothyroidism (sHT).Materials and Methods.We selected 17 sedentary women with sHT (mean age: 43.1 (standard deviation: 9.7) years). Participants carried out an MIEP consisting of 3 weekly sessions of 60 minutes during 12 weeks. Before and after the exercise program HRQoL was assessed by the SF-12v2 questionnaire, andVO2maxwas evaluated by Rockport walk test.Results.After the 12-week intervention, the participants that performed an MIEP showed improvements in HRQoL in most domains, particularly the vitality domain by 7 points, the social functioning domain by 10 points, the mental health domain by 7 points, and the mental component summary by 7 points. One of the four domains within the physical component summary (general health domain) showed significant effect of the exercise intervention: 6 points. Moreover, the participants that performed exercise showed a higherVO2max(28%;P<0.01).Conclusion.After 12 weeks of medium-impact exercise program, there were remarkable improvements in HRQoL in most domains. Moreover, this exercise program proved to have a positive influence on cardiorespiratory fitness.

scholarly journals Cardiovascular Risk Factors, Functionality, and Quality of Life in Climacteric Women

2021 ◽  
Author(s):  
João Vítor Costa dos Santos Chaves ◽  
Keila Lindineia Silva Pinto ◽  
Kleicillainy Mota de Sousa ◽  
Lucas Oliveira Soares ◽  
André Luiz Lisboa Cordeiro
Keyword(s):  
Quality Of Life ◽  
Risk Factors ◽  
Cardiovascular Risk ◽  
Cardiovascular Risk Factors

Erectile dysfunction in patients with arterial hypertension. Cardiovascular risk and impact on their quality of life

2019 ◽  
Vol 152 (6) ◽  
pp. 209-215
Author(s):  
Mónica Diosdado-Figueiredo ◽  
Vanesa Balboa-Barreiro ◽  
Sonia Pértega-Diaz ◽  
Teresa Seoane-Pillado ◽  
Salvador Pita-Fernández ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Erectile Dysfunction ◽  
Cardiovascular Risk ◽  
Arterial Hypertension

Metabolic profile, cardiovascular risk factors and health-related quality of life in children, adolescents and young adults with congenital adrenal hyperplasia

2019 ◽  
Vol 32 (8) ◽  
pp. 871-877 ◽  
Author(s):  
Roopa Vijayan ◽  
Nisha Bhavani ◽  
Praveen V. Pavithran ◽  
Vasantha Nair ◽  
Usha V. Menon ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Risk Factors ◽  
Cardiovascular Risk ◽  
Congenital Adrenal Hyperplasia ◽  
Cardiovascular Risk Factors ◽  
Metabolic Profile ◽  
Good Control ◽  
Adrenal Hyperplasia ◽  
Age And Sex

Abstract Background The present study was designed to evaluate the metabolic profile, cardiovascular risk factors and quality of life in children with congenital adrenal hyperplasia (CAH) and compare it with age- and sex-matched controls. Methods Fifty-two patients aged 3–21 years with classic CAH due to 21-hydroxylase deficiency were included in the study. Metabolic profiling was done for 36 cases and compared with 28 healthy age- and sex-matched controls. Quality of life was assessed in all 52 children and their parents using a validated Pediatric Quality of Life Inventory (PedsQL) questionnaire and was compared with normative data from the same population. Results The median age was 12 years with 14 (27%) males and 38 (73%) females. Out of the total 52 patients, 35 (67%) had salt wasting and 17 (33%) had simple virilising CAH. The median height standard deviation score (SDS) of cases was similar to that of controls (−0.72 vs. −0.64, p = 0.57) and 81% of females had normal pubertal status indicating a good control of the disease. Weight SDS, body mass index (BMI) SDS, mean diastolic blood pressure and insulin resistance were significantly higher in cases when compared to controls (0.31 vs. −0.3; 0.96 vs. 0.17; 67.8 ± 10.49 vs. 61 ± 8.49 and 2.1 vs. 0.95, respectively). The quality of life was significantly reduced in all domains as per parents’ perspective, whereas the children reported reduced quality of social and school functioning. There was no significant correlation between quality of life and metabolic parameters. Conclusions Children with CAH despite a reasonably good control of the disease have a higher cardiovascular risk and reduced quality of life when compared to healthy controls.

scholarly journals PCV119 Relationship Between Quality of Life and Level of Cardiovascular Risk and Comorbidities in Spanish Hipertensive Patients-Alhambra Study

2011 ◽  
Vol 14 (7) ◽  
pp. A386
Author(s):  
B. Font ◽  
R. Lahoz ◽  
J. Salazar ◽  
A. Roca-cusachs ◽  
A. Abellán
Keyword(s):  
Quality Of Life ◽  
Cardiovascular Risk
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