scholarly journals Consensus and evidence-based medication review to optimize and potentially reduce psychotropic drug prescription in institutionalized dementia patients

2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Mireia Massot Mesquida ◽  
Montserrat Tristany Casas ◽  
Alicia Franzi Sisó ◽  
Isabel García Muñoz ◽  
Óscar Hernández Vian ◽  
...  
Keyword(s):  
Psychotropic Drug ◽  
Medication Review ◽  
Drug Prescription ◽  
Evidence Based ◽  
Dementia Patients

P412: Factors related to psychotropic drug prescription for neuropsychiatric symptoms in institutionalized dementia patients

2014 ◽  
Vol 5 ◽  
pp. S211
Author(s):  
C.H.W. Smeets ◽  
M. Smalbrugge ◽  
S.U. Zuidema ◽  
E.W.C. Derksen ◽  
E. de Vries ◽  
...  
Keyword(s):  
Psychotropic Drug ◽  
Neuropsychiatric Symptoms ◽  
Drug Prescription ◽  
Dementia Patients

scholarly journals Cost-utility analysis of a consensus and evidence-based medication review to optimize and potentially reduce psychotropic drug prescription in institutionalized dementia patients

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Mireia Massot Mesquida ◽  
Frans Folkvord ◽  
Gemma Seda ◽  
Francisco Lupiáñez-Villanueva ◽  
Pere Torán Monserrat
Keyword(s):  
Cost Effectiveness ◽  
Psychotropic Drugs ◽  
Medication Review ◽  
Standard Care ◽  
Cost Utility ◽  
Cost Utility Analysis ◽  
Utility Analysis ◽  
Current Standard ◽  
Dementia Patients ◽  
The Cost

Abstract Background Growing evidence shows the effects of psychotropic drugs on the evolution of dementia. Until now, only a few studies have evaluated the cost-effectiveness of psychotropic drugs in institutionalized dementia patients. This study aims to assess the cost-utility of intervention performed in the metropolitan area of Barcelona (Spain) (MN) based on consensus between specialized caregivers involved in the management of dementia patients for optimizing and potentially reducing the prescription of inappropriate psychotropic drugs in this population. This analysis was conducted using the Monitoring and Assessment Framework for the European Innovation Partnership on Active and Healthy Ageing (MAFEIP) tool. Methods The MAFEIP tool builds up from a variety of surrogate endpoints commonly used across different studies in order to estimate health and economic outcomes in terms of incremental changes in quality adjusted life years (QALYs), as well as health and social care utilization. Cost estimates are based on scientific literature and expert opinion; they are direct costs and include medical visits, hospital care, medical tests and exams and drugs administered, among other concepts. The healthcare costs of patients using the intervention were calculated by means of a medication review that compared patients’ drug-related costs before, during and after the use of the intervention conducted in MN between 2012 and 2014. The cost-utility analysis was performed from the perspective of a health care system with a time horizon of 12 months. Results The tool calculated the incremental cost-effectiveness ratio (ICER) of the intervention, revealing it to be dominant, or rather, better (more effective) and cheaper than the current (standard) care. The ICER of the intervention was in the lower right quadrant, making it an intervention that is always accepted even with the lowest given Willingness to Pay (WTP) threshold value (€15,000). Conclusions The results of this study show that the intervention was dominant, or rather, better (more effective) and cheaper than the current (standard) care. This dominant intervention is therefore recommended to interested investors for systematic application.

scholarly journals Evaluation of Psychotropic Drug Use in Adolescents Accessing a General Emergency Medical Department for Mental Disorders

Adolescents ◽  
2020 ◽  
Vol 1 (1) ◽  
pp. 1-9
Author(s):  
Martina Buttera ◽  
Antonio Clavenna ◽  
Lucia Tansini ◽  
Erica Maselli ◽  
Alessandro Albizzati ◽  
...  
Keyword(s):  
Drug Use ◽  
Mental Disorders ◽  
Mental Disorder ◽  
Psychotropic Drug ◽  
Pediatric Population ◽  
Drug Prescription ◽  
University Hospital ◽  
Medical Department ◽  
Off Label ◽  
Psychotropic Drug Use

Background: Given the paucity of data concerning the care of adolescents attending an emergency department (ED) for mental disorders, we performed an observational study with the aim to describe psychotropic drug use in an Italian ED. Methods: A retrospective chart review of adolescents (13–17 years) visited in the ED of the San Paolo University Hospital in Milan for mental disorders between January and June 2018 was conducted. Information concerning age, gender, type of disorder, psychotropic drug use in the ED and outcome of the visit were analyzed, using an anonymous patient code. Results: A total of 1298 adolescents, 13–17 years old, were visited in the ED, 56 (4%) of whom had a diagnosis of mental disorder (34 females and 22 males). The most common disorder was anxiety (21 patients), followed by predominant psychomotor disorder (13 patients). In all, 30 adolescents received a psychotropic drug. Benzodiazepines were the most commonly used drugs (73% of the subjects), and delorazepam was administered/prescribed to 17 adolescents, despite the fact that evidence on its safety, efficacy, and its off-label use in the pediatric population is lacking. Conclusions: One out of two adolescents attending the ED for an acute episode of mental disorder received a psychotropic drug prescription, mainly in an off-label manner. More evidence is needed to guide the pharmacological management of acute episodes of mental disorders.

Psychotropic drug prescription patterns among patients with bipolar I disorder

2000 ◽  
Vol 2 (2) ◽  
pp. 120-130 ◽  
Author(s):  
Joseph Levine ◽  
Kn Roy Chengappa ◽  
Jaspreet S Brar ◽  
Samuel Gershon ◽  
Eric Yablonsky ◽  
...  
Keyword(s):  
Psychotropic Drug ◽  
Drug Prescription ◽  
Bipolar I Disorder ◽  
Prescription Patterns

Psychotropic Drug Prescription in Patients with Dementia: Nursing Home Residents Versus Patients Living at Home

2015 ◽  
Vol 49 (3) ◽  
pp. 671-680 ◽  
Author(s):  
Agnès Jacquin-Piques ◽  
Guillaume Sacco ◽  
Neda Tavassoli ◽  
Olivier Rouaud ◽  
Yannick Bejot ◽  
...  
Keyword(s):  
Nursing Home ◽  
Psychotropic Drug ◽  
Drug Prescription ◽  
Nursing Home Residents ◽  
At Home

Deliberate self-poisoning presenting at a rural hospital in Northern Ireland 1976–1996: relationship to prescribing

2000 ◽  
Vol 15 (6) ◽  
pp. 348-353 ◽  
Author(s):  
C.B. Kelly ◽  
J. Weir ◽  
T. Rafferty ◽  
R. Galloway
Keyword(s):  
Northern Ireland ◽  
Rural Area ◽  
Psychotropic Drug ◽  
Rural Areas ◽  
Drug Prescription ◽  
Defined Daily Dose ◽  
Toxic Agent ◽  
Female Ratio ◽  
The Face ◽  
Urban And Rural Areas

summaryPurpose – This study reports on a project to monitor deliberate self-poisoning in a rural area of Northern Ireland over a 20-year period. Comparison is made with reports from large urban centres. In addition, a local prescribing database allows assessment of any association between psychotropic drug prescription and use for deliberate self-poisoning. Materials and methods – Frequency of self-poisoning, demographic details and drugs used were recorded for all episodes of deliberate self-poisoning occurring at Craigavon Area Hospital for the years 1976, 1986, 1991 and 1996. It was possible to compare prescriptions of psychotropic drugs with their use for deliberate self-poisoning between the years 1991 and 1996 in the region served by the hospital, using the Defined Daily Dose (DDD) system. Results – In this rural area the pattern of deliberate self-poisoning has changed, as in urban centres, with a rise in frequency and the male/female ratio approaching unity. The pattern of drug use has altered, with paracetamol overtaking benzodiazepines as the most commonly used agent. More recently, antidepressants have become the second most frequently used drug class for this purpose. Psychotropic medications used for self-poisoning altered in proportion to their prescription between the years 1991 and 1996. Conclusions – In the face of a continuing rise in deliberate self-poisoning, which is effecting both urban and rural areas, care should be taken to prescribe the least toxic agent available as this is associated with likely frequency of self-poisoning for most classes of psychotropic drug.

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