scholarly journals Human cytomegalovirus and Epstein-Barr virus infections, risk factors, and their influence on the liver function of patients with acute-on-chronic liver failure

2018 ◽  
Vol 18 (1) ◽  
Author(s):  
Jianhua Hu ◽  
Hong Zhao ◽  
Danfeng Lou ◽  
Hainv Gao ◽  
Meifang Yang ◽  
...  
2017 ◽  
Vol 23 (3) ◽  
pp. 483-490 ◽  
Author(s):  
Alexandra Laberko ◽  
Anna Bogoyavlenskaya ◽  
Larisa Shelikhova ◽  
Zhanna Shekhovtsova ◽  
Dmitriy Balashov ◽  
...  

2021 ◽  
pp. 1-7
Author(s):  
Hadi Ghaffari ◽  
Ahmad Tavakoli ◽  
Nahid Nafissi ◽  
Mohammad Farahmand ◽  
Saied Ghorbani ◽  
...  

BACKGROUND AND OBJECTIVES: The role of human cytomegalovirus (HCMV) and Epstein-Barr virus (EBV) infections in breast cancer pathology is not well understood. Our study aimed to investigate the association of HCMV and EBV infections with breast cancer and distinguish the types of positive EBV and LMP-1 samples in Iranian patients. METHODS: Seventy-two formalin-fixed paraffin-embedded (FFPE) breast cancer tissues were analyzed between December 2014 and April 2016. Samples were analyzed for HCMV and EBV using nested-PCR and conventional PCR assays, respectively. Statistical analysis was performed using SPSS software version 18. RESULTS: Overall, HCMV and EBV genomes were detected in 6.9% and 16.7% of FFPE breast cancer tissues, respectively. Clinical factors were not statistically associated with the presence of HCMV and EBV. CONCLUSION: In this study, we reported EBV and LMP-1 typing in breast carcinoma cases for the first time in Iran. Our findings indicate that HCMV and EBV infections are not associated with the development of breast cancer.


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