scholarly journals Risk factors for viral hepatitis C infection in Rwanda: results from a nationwide screening program

2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Jean Damascene Makuza ◽  
Carol Y. Liu ◽  
Corneille Killy Ntihabose ◽  
Donatha Dushimiyimana ◽  
Sabine Umuraza ◽  
...  
Keyword(s):  
Risk Factors ◽  
Hepatitis C ◽  
Viral Hepatitis ◽  
Screening Program ◽  
Hepatitis C Infection ◽  
Viral Hepatitis C

scholarly journals Risk factors for viral hepatitis C infection in Rwanda: Results from a Nationwide Screening Program

2019 ◽  
Author(s):  
Jean Damascene Makuza ◽  
Carol Y Liu ◽  
Corneille Killy Ntihabose ◽  
Donatha Dushimiyimana ◽  
Sabine Umuraza ◽  
...  
Keyword(s):  
Risk Factors ◽  
Hepatitis C ◽  
Viral Hepatitis ◽  
Screening Program ◽  
Case Finding ◽  
Public Health Approach ◽  
Sample Collection ◽  
Hepatitis C Infection ◽  
Viral Hepatitis C ◽  
History Of

Abstract Background: The epidemiology and risk factors for hepatitis C virus (HCV) infection in Rwanda are not well known; however, this information is crucial to shaping the country’s public health approach to hepatitis C control. Methods: A HCV screening campaign was conducted in the general population in 24 districts previously identified to have a high HCV disease burden. At the time of sample collection, sociodemographic information and self-reported risk factors were collected. Bivariate and multivariate logistic regressions were conducted to assess risk factors independently associated with hepatitis C antibodies (HCVAb) seroprevalence. Results: Out of a total of 326,263 individuals screened for HCVAb, 22,183 (6.8%) were positive. In multivariate analysis, risk factors identified as statistically associated with HCVAb Seroprevalence include history of traditional operation or scarification (OR=1.09, 95% CI: 1.05-1.14), presence of viral hepatitis in the family (OR=1.27, 95% CI: 1.15-1.40), widowed or separated/divorced (OR=1.36, 95% CI: 1.26-1.47), Southern province (OR=1.98, 95% CI: 1.88-2.08) and aged 65 years and older (OR=4.86, 95% CI: 4.62-5.11). Ubudehe category 3 (OR=0.97, 95% CI: 0.93-1.01) and participants using RAMA (Health insurances for employees of public and private sectors) insurance (OR=0.76, 95% CI: 0.70-0.85) had lower odds of HCV seroprevalence. Conclusions: Our findings provide important information for Rwanda’s strategy on prevention and case-finding. Future prevention interventions should aim to reduce transmission through targeted messaging around traditional healing practices and case-finding targeting individuals with a history of exposure or advanced age.

scholarly journals Risk factors for viral hepatitis C infection in Rwanda: Results from a Nationwide Screening Program

2019 ◽  
Author(s):  
Jean Damascene Makuza ◽  
Carol Y Liu ◽  
Corneille Killy Ntihabose ◽  
Donatha Dushimiyimana ◽  
Sabine Umuraza ◽  
...  
Keyword(s):  
Risk Factors ◽  
Hepatitis C ◽  
Viral Hepatitis ◽  
Screening Program ◽  
Case Finding ◽  
Public Health Approach ◽  
Sample Collection ◽  
Hepatitis C Infection ◽  
Viral Hepatitis C ◽  
History Of

Abstract Background: The epidemiology and risk factors for hepatitis C virus (HCV) infection in Rwanda are not well known; however, this information is crucial to shaping the country’s public health approach to hepatitis C control. Methods: A HCV screening campaign was conducted in the general population in 24 districts previously identified to have a high HCV disease burden. At the time of sample collection, sociodemographic information and self-reported risk factors were collected. Bivariate and multivariate logistic regressions were conducted to assess risk factors independently associated with hepatitis C antibodies (HCVAb) seroprevalence. Results: Out of a total of 326,263 individuals screened for HCVAb, 22,183 (6.8%) were positive. In multivariate analysis, risk factors identified as statistically associated with HCVAb Seroprevalence include history of traditional operation or scarification (OR=1.09, 95% CI: 1.05-1.14), presence of viral hepatitis in the family (OR=1.27, 95% CI: 1.15-1.40), widowed or separated/divorced (OR=1.36, 95% CI: 1.26-1.47), Southern province (OR=1.98, 95% CI: 1.88-2.08) and aged 65 years and older (OR=4.86, 95% CI: 4.62-5.11). Ubudehe category 3 (OR=0.97, 95% CI: 0.93-1.01) and participants using RAMA (Health insurances for employees of public and private sectors) insurance (OR=0.76, 95% CI: 0.70-0.85) had lower odds of HCV seroprevalence. Conclusions: Our findings provide important information for Rwanda’s strategy on prevention and case-finding. Future prevention interventions should aim to reduce transmission through targeted messaging around traditional healing practices and case-finding targeting individuals with a history of exposure or advanced age.

scholarly journals Risk factors for viral hepatitis C infection in Rwanda: Results from a Nationwide Screening Program

2019 ◽  
Author(s):  
Jean Damascene Makuza ◽  
Carol Y Liu ◽  
Corneille Killy Ntihabose ◽  
Donatha Dushimiyimana ◽  
Sabine Umuraza ◽  
...  
Keyword(s):  
Risk Factors ◽  
Hepatitis C ◽  
Viral Hepatitis ◽  
Screening Program ◽  
Case Finding ◽  
Public Health Approach ◽  
Sample Collection ◽  
Hepatitis C Infection ◽  
Viral Hepatitis C ◽  
History Of

Abstract Background: The epidemiology and risk factors for hepatitis C virus (HCV) infection in Rwanda are not well known; however, this information is crucial to shaping the country’s public health approach to hepatitis C control. Methods: A HCV screening campaign was conducted in the general population in 24 districts previously identified to have a high HCV disease burden. At the time of sample collection, sociodemographic information and self-reported risk factors were collected. Bivariate and multivariate logistic regressions were conducted to assess risk factors independently associated with hepatitis C antibodies (HCVAb) seroprevalence. Results: Out of a total of 326,263 individuals screened for HCVAb, 22,183 (6.8%) were positive. In multivariate analysis, risk factors identified as statistically associated with HCVAb Seroprevalence include history of traditional operation or scarification (OR=1.09, 95% CI: 1.05-1.14), presence of viral hepatitis in the family (OR=1.27, 95% CI: 1.15-1.40), widowed or separated/divorced (OR=1.36, 95% CI: 1.26-1.47), Southern province (OR=1.98, 95% CI: 1.88-2.08) and aged 65 years and older (OR=4.86, 95% CI: 4.62-5.11). Ubudehe category 3 (OR=0.97, 95% CI: 0.93-1.01) and participants using RAMA (Health insurances for employees of public and private sectors) insurance (OR=0.76, 95% CI: 0.70-0.85) had lower odds of HCV seroprevalence. Conclusions: Our findings provide important information for Rwanda’s strategy on prevention and case-finding. Future prevention interventions should aim to reduce transmission through targeted messaging around traditional healing practices and case-finding targeting individuals with a history of exposure or advanced age.

scholarly journals Risk factors for viral hepatitis C infection in Rwanda: Results from a Nationwide Screening Program

2019 ◽  
Author(s):  
Jean Damascene Makuza ◽  
Carol Y Liu ◽  
Corneille Killy Ntihabose ◽  
Donatha Dushimiyimana ◽  
Sabine Umuraza ◽  
...  
Keyword(s):  
Risk Factors ◽  
Hepatitis C ◽  
Viral Hepatitis ◽  
Screening Program ◽  
Case Finding ◽  
Public Health Approach ◽  
Sample Collection ◽  
Hepatitis C Infection ◽  
Viral Hepatitis C ◽  
History Of

Abstract Background The epidemiology and risk factors for hepatitis C virus (HCV) infection in Rwanda are not well known; however, this information is crucial to shaping the country’s public health approach to hepatitis C control. Methods A HCV screening campaign was conducted in the general population in 24 districts previously identified to have a high HCV disease burden at the time of sample collection, sociodemographic information and self-reported risk factors were collected. Bivariate and multivariate logistic regressions were conducted to assess risk factors independently associated with HCVAb seroprevalence. Results Out of a total of 326,263 individuals screened for HCVAb, 22183 (6.8%) were positive. In multivariate analysis, risk factors identified as statistically associated with HCVAb positivity include history of traditional operation or scarification (OR=1.091, 95% CI: 1.049-1.135), presence of viral hepatitis in the family (OR=1.268, 95% CI: 1.151-1.397), widowed or separated/divorced (OR=1.36, 95% CI: 1.257-1.471), South province (OR=1.978, 95% CI: 1.884-2.077) and age 65 years old and over (OR=4.857, 95% CI: 4.617-5.110). Ubudehe category 3 (OR=0.966, 95% CI: 0.927-1.008) and participants using RAMA insurance (OR=0.775, 95% CI: 0.704-0.854) had lower odds of HCV seropositivity. Conclusions Our findings provide important information for Rwanda’s strategy on prevention and case-finding. Future prevention interventions will aim to reduce transmission through targeted messaging around traditional healing practices and future case-finding will target individuals with a history of exposure or of older age.

scholarly journals Risk factors for hepatitis C virus infection

2003 ◽  
Vol 56 (11-12) ◽  
pp. 511-515
Author(s):  
Zeljko Mijailovic ◽  
Predrag Canovic ◽  
Olgica Gajovic ◽  
Zoran Todorovic ◽  
Ljiljana Nesic
Keyword(s):  
Risk Factors ◽  
Risk Factor ◽  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Viral Infection ◽  
Viral Hepatitis ◽  
Study Group ◽  
Hepatitis C Infection ◽  
Major Health Problem ◽  
Viral Hepatitis C

Introduction Hepatitis C viral infection represents a major health problem in the world. The estimated global incidence is about 3%, whereas the number of chronic hepatitis C virus (HCV) carriers worldwide is estimated to be between 150-300 million people. Material and methods This retrospective analysis included 82 patients whose diagnosis of viral hepatitis C infection was based upon the following criteria: case history, physical examination, laboratory and abdominal ultrasound examination, histological examination of the liver, radiological examination, serological analysis and viral analysis. Descriptive statistics were used to describe general data on patients of the study group, risk factor analysis and follow-up results. Results The most prominent risk factor in our study group was intravenous use of drugs in 37 patients (37%), and blood transfusion in 13 patients (13%). Less important risk factors of viral hepatitis C infection included: promiscuity (8%), sexual contact with hepatitis C carriers (5%), surgical intervention (5%), haemodialysis (3%), intranasal use of cocaine (2%). Discussion Hepatitis C viral infection has become the illness of young and middle-aged population. This is due to the epidemic profile of this illness, due to intravenous use of drugs as the most prominent risk factor. Conclusion Due to the number of infected, numerous risk factors and complications of viral hepatitis C, hepatitis C virus has become the most prominent hepatotrophic virus.

scholarly journals Viral hepatitis C and B among dialysis patients at the Rabat University Hospital: Prevalence and risk factors

2014 ◽  
Vol 25 (3) ◽  
pp. 672 ◽  
Author(s):  
Zineb Lioussfi ◽  
Zineb Errami ◽  
Aicha Radoui ◽  
Hakima Rhou ◽  
Fatima Ezzaitouni ◽  
...  
Keyword(s):  
Risk Factors ◽  
Hepatitis C ◽  
Viral Hepatitis ◽  
University Hospital ◽  
Dialysis Patients ◽  
Viral Hepatitis C

scholarly journals 1319Epidemiology and Risk Factors for Viral Hepatitis C in Oran

2021 ◽  
Vol 50 (Supplement_1) ◽  
Author(s):  
Lakhdar Zemour ◽  
Nassima Amani ◽  
Lynda mallem ◽  
AMINA Belghitri ◽  
Nori Midoun
Keyword(s):  
Risk Factors ◽  
Hepatitis C ◽  
Viral Hepatitis ◽  
Chronic Viral Hepatitis ◽  
University Hospital ◽  
Traditional Practices ◽  
Cross Sectional ◽  
Awareness Campaigns ◽  
Viral Hepatitis C ◽  
Epidemiological Profile

Abstract Introduction The clinical epidemiological profile of patients with viral hepatitis C appears to differ from population. It is well established that in the West, the two main modes of hepatitis C virus contamination are blood transfusion and addiction. However, in our region, risk factors for transmission remain poorly identified and poorly quantified Thus, the objective of this study is to chart the epidemiological profile and to show the share of the different risk factors reported among the modes of transmission of HCV in this category of Oranese patients. Methods A cross-sectional study was conducted with patients with chronic viral hepatitis C, admitted to the gastroenterology services of the Oran University Hospital and prospectively collected from 2009 until 2015 for therapeutic management. The data were collected using a standardized questionnaire and processed on SPSS 20.0. Results There are 289 cases of viral hepatitis C; female predominance (sex ratio of 0.56). Their average age is 48.9±12.9 years. The G1 genotype is slightly with a frequency of 48.4% followed by the G2 with 37.7%. Among the probable modes of contamination reported, dental care ranked first with 54.7% followed by surgical procedures in 26.3%. Traditional practices such as hijama and scarification were found in 51.9% of cases. Conclusion Apart from the known contamination factors in the literature, we must not overlook the very important part of traditional practices that are closely linked to the traditions and beliefs of our region. Awareness campaigns should be adopted on hygiene practices to ensure good care safety. Keywords HCV, Contamination Patterns, Genotype, Risk

Viral hepatitis C infection among injecting drug users and their partners in Manipur

2021 ◽  
Vol 2 (1) ◽  
pp. 9
Author(s):  
RomeoSingh Karam ◽  
ThangjamDhabali Singh ◽  
BrogenSingh Akoijam ◽  
Nalinikanta Rajkumar
Keyword(s):  
Hepatitis C ◽  
Viral Hepatitis ◽  
Drug Users ◽  
Injecting Drug Users ◽  
Hepatitis C Infection ◽  
Viral Hepatitis C

scholarly journals Similar Low Rates of HCV Recurrence in HCV/HIV- and HCV-Infected Participants who Achieved SVR After DAA Treatment: Interim Results From the ACTG A5320 Viral Hepatitis C Infection Long-term Cohort Study (V-HICS)

2018 ◽  
Vol 5 (6) ◽  
Author(s):  
David L Wyles ◽  
Minhee Kang ◽  
Roy M Matining ◽  
Robert L Murphy ◽  
Marion G Peters ◽  
...  
Keyword(s):  
Cohort Study ◽  
Hepatitis C Virus ◽  
Hepatitis C ◽  
High Risk ◽  
Viral Hepatitis ◽  
Low Risk ◽  
Hepatitis C Infection ◽  
Recurrence Rates ◽  
Viral Hepatitis C

Abstract Hepatitis C virus (HCV) recurrence rates were similar between those with HCV/HIV co-infection (0.35/100 person-years) and HCV infection (0.42/100 person-years). Low rates of recurrence likely represent enrollment of an HIV population at low risk for recurrence. Care should be taken not to label all HCV/HIV co-infected patients as being at high risk for HCV recurrence.

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