scholarly journals Similar Low Rates of HCV Recurrence in HCV/HIV- and HCV-Infected Participants who Achieved SVR After DAA Treatment: Interim Results From the ACTG A5320 Viral Hepatitis C Infection Long-term Cohort Study (V-HICS)

2018 ◽  
Vol 5 (6) ◽  
Author(s):  
David L Wyles ◽  
Minhee Kang ◽  
Roy M Matining ◽  
Robert L Murphy ◽  
Marion G Peters ◽  
...  
Keyword(s):  
Cohort Study ◽  
Hepatitis C Virus ◽  
Hepatitis C ◽  
High Risk ◽  
Viral Hepatitis ◽  
Low Risk ◽  
Hepatitis C Infection ◽  
Recurrence Rates ◽  
Viral Hepatitis C

Abstract Hepatitis C virus (HCV) recurrence rates were similar between those with HCV/HIV co-infection (0.35/100 person-years) and HCV infection (0.42/100 person-years). Low rates of recurrence likely represent enrollment of an HIV population at low risk for recurrence. Care should be taken not to label all HCV/HIV co-infected patients as being at high risk for HCV recurrence.

scholarly journals Continued low rates of HCV recurrence in HCV/HIV and HCV infected participants who achieved SVR after DAA treatment: Final results from the ACTG A5320 Viral Hepatitis C Infection Long-term Cohort Study (V-HICS)

2021 ◽  
Author(s):  
David L Wyles ◽  
Minhee Kang ◽  
Roy M Matining ◽  
Robert L Murphy ◽  
Marion G Peters
Keyword(s):  
Cohort Study ◽  
Hepatitis C ◽  
High Risk ◽  
Viral Hepatitis ◽  
Risk Behaviors ◽  
Hepatitis C Infection ◽  
High Risk Behaviors ◽  
Viral Hepatitis C

Abstract Final results from the long-term VHICS cohort found low rates of HCV recurrence after DAA therapy in both HCV/HIV (0.67/100 p-y) and HCV (0.2/100 p-y) groups with over 500 person years of follow-up. Confirmed re-infections were in participants with HIV who reported high-risk behaviors.

Quality of life in long-term survivors after liver transplantation: impact of recurrent viral hepatitis C virus hepatitis 1

2000 ◽  
Vol 14 (1) ◽  
pp. 48-54 ◽  
Author(s):  
David L Paterson ◽  
Timothy Gayowski ◽  
Cheryl F Wannstedt ◽  
Marilyn M Wagener ◽  
Ignazio R Marino ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Liver Transplantation ◽  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Viral Hepatitis ◽  
Virus Hepatitis ◽  
Viral Hepatitis C ◽  
Long Term Survivors

scholarly journals Risk factors for hepatitis C virus infection

2003 ◽  
Vol 56 (11-12) ◽  
pp. 511-515
Author(s):  
Zeljko Mijailovic ◽  
Predrag Canovic ◽  
Olgica Gajovic ◽  
Zoran Todorovic ◽  
Ljiljana Nesic
Keyword(s):  
Risk Factors ◽  
Risk Factor ◽  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Viral Infection ◽  
Viral Hepatitis ◽  
Study Group ◽  
Hepatitis C Infection ◽  
Major Health Problem ◽  
Viral Hepatitis C

Introduction Hepatitis C viral infection represents a major health problem in the world. The estimated global incidence is about 3%, whereas the number of chronic hepatitis C virus (HCV) carriers worldwide is estimated to be between 150-300 million people. Material and methods This retrospective analysis included 82 patients whose diagnosis of viral hepatitis C infection was based upon the following criteria: case history, physical examination, laboratory and abdominal ultrasound examination, histological examination of the liver, radiological examination, serological analysis and viral analysis. Descriptive statistics were used to describe general data on patients of the study group, risk factor analysis and follow-up results. Results The most prominent risk factor in our study group was intravenous use of drugs in 37 patients (37%), and blood transfusion in 13 patients (13%). Less important risk factors of viral hepatitis C infection included: promiscuity (8%), sexual contact with hepatitis C carriers (5%), surgical intervention (5%), haemodialysis (3%), intranasal use of cocaine (2%). Discussion Hepatitis C viral infection has become the illness of young and middle-aged population. This is due to the epidemic profile of this illness, due to intravenous use of drugs as the most prominent risk factor. Conclusion Due to the number of infected, numerous risk factors and complications of viral hepatitis C, hepatitis C virus has become the most prominent hepatotrophic virus.

scholarly journals Risk factors for viral hepatitis C infection in Rwanda: results from a nationwide screening program

2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Jean Damascene Makuza ◽  
Carol Y. Liu ◽  
Corneille Killy Ntihabose ◽  
Donatha Dushimiyimana ◽  
Sabine Umuraza ◽  
...  
Keyword(s):  
Risk Factors ◽  
Hepatitis C ◽  
Viral Hepatitis ◽  
Screening Program ◽  
Hepatitis C Infection ◽  
Viral Hepatitis C

scholarly journals Maternal Hepatitis B Virus or Hepatitis C Virus Carrier Status and Long-Term Endocrine Morbidity of the Offspring—A Population-Based Cohort Study

2020 ◽  
Vol 9 (3) ◽  
pp. 796 ◽  
Author(s):  
Naim Abu Freha ◽  
Tamar Wainstock ◽  
Tzvi Najman Menachem ◽  
Eyal Sheiner
Keyword(s):  
Cohort Study ◽  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Hepatitis B Virus ◽  
Hepatitis B ◽  
Cox Regression ◽  
Population Based ◽  
Carrier Status ◽  
B Virus

This study aimed to investigate the long-term effect of maternal hepatitis B virus (HBV) or hepatitis C virus (HCV) carrier status on offspring endocrine morbidity. A population-based cohort study included all singleton deliveries between the years 1991–2014 at the Soroka University Medical Center, Beer-Sheva, Southern Israel. The mothers were subdivided into three groups, HBV carriers, HCV carriers and non-carriers. Data regarding the long-term endocrine morbidity of their offspring were compared between the groups. The study included 242,905 (99.7%) non-carrying mothers, 591 (0.2%) mothers who were carriers for HBV and 186 (0.1%) mothers who were carriers for HCV. The Kaplan–Meier’s survival curve demonstrated a significantly higher cumulative endocrine morbidity in children born to mothers with HCV (log-rank test, p = 0.002). Specifically, higher rates of hypoglycemia were noted among the offspring born to mothers who were carriers of HCV (1.1%; p = 0.001) compared with the offspring of mothers who were either carriers of HBV (0.2%) or non-carriers (0.1%). A Cox regression model controlled for maternal age, gestational age, maternal diabetes, hypertensive disorders of pregnancy, found maternal HCV carrier status to be independently associated with pediatric endocrine morbidity in the offspring (adjusted hazard ratio = 5.05, 95% CI: 1.625–15.695, p = 0.005). Maternal HCV carrier status is an independent risk factor for long-term endocrine morbidity.

The long-term effects of anti-TNF-α agents on patients with chronic viral hepatitis C and B infections

2014 ◽  
Vol 18 (1) ◽  
pp. 40-45 ◽  
Author(s):  
Tuncer Temel ◽  
Döndü Üsküdar Cansu ◽  
Cengiz Korkmaz ◽  
Timuçin Kaşifoğlu ◽  
Ayşegül Özakyol
Keyword(s):  
Hepatitis C ◽  
Viral Hepatitis ◽  
Chronic Viral Hepatitis ◽  
Long Term Effects ◽  
Viral Hepatitis C ◽  
Tnf Α ◽  
Chronic Viral Hepatitis C

scholarly journals Cryoglobulinemic vasculitis as an extrahepatic manifestation of HCV infec- tion

2021 ◽  
Vol 98 (9-10) ◽  
pp. 709-712
Author(s):  
A. E. Geraskin ◽  
L. M. Mosina ◽  
L. V. Chegodaeva
Keyword(s):  
Hepatitis C ◽  
Viral Hepatitis ◽  
Antiviral Therapy ◽  
Systemic Disease ◽  
Clinical Manifestations ◽  
Cryoglobulinemic Vasculitis ◽  
Autoimmune Pathology ◽  
Viral Hepatitis C ◽  
Autoimmune Processes

The problem of viral hepatitis C remains highly relevant despite the recent signifi cant advancements in the diagnosis and treatment of this pathology. Chronic hepatitis C is a systemic disease with extrahepatic manifestations. Autoimmune processes leading to cryoglobulinemia can contribute to their development. Basic clinical manifestations include cutaneous vasculitis with palpable purpura, arthralgia-myalgia, neuropathy, and renal complications such as glomerulonephritis. Polyneuropathies develop much earlier than hepatic encephalopathy, which is characteristic of liver damage. A clinical case represented in the article was noted in a patient with a long-term course of viral hepatitis C, manifested with pronounced neurological symptoms and the development of cryoglobulinemic vasculitis. In this case, of all the applied methods of treatment, only adequately conducted antiviral therapy contributed to the stabilization of the clinical manifestations of cryoglobulinemia. The promptness of antiviral therapy is of signifi cant importance, since it is a possibility to prevent the development of severe autoimmune pathology.

Viral hepatitis C infection among injecting drug users and their partners in Manipur

2021 ◽  
Vol 2 (1) ◽  
pp. 9
Author(s):  
RomeoSingh Karam ◽  
ThangjamDhabali Singh ◽  
BrogenSingh Akoijam ◽  
Nalinikanta Rajkumar
Keyword(s):  
Hepatitis C ◽  
Viral Hepatitis ◽  
Drug Users ◽  
Injecting Drug Users ◽  
Hepatitis C Infection ◽  
Viral Hepatitis C
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