scholarly journals Toxic shock syndrome complicated with symmetrical peripheral gangrene after liposuction and fat transfer: a case report and literature review

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Zhiwan Liu ◽  
Wenjun Zhang ◽  
Boyu Zhang ◽  
Linhao Ma ◽  
Feng Zhou ◽  
...  
Keyword(s):  
Toxic Shock Syndrome ◽  
Vital Signs ◽  
Good Health ◽  
Multiple Organ ◽  
Skin Grafts ◽  
Toxic Shock ◽  
Fat Transfer ◽  
Autologous Fat Transfer ◽  
Peripheral Gangrene ◽  
Thickness Skin

Abstract Background Liposuction is one of the most commonly performed aesthetic procedures. Toxic shock syndrome(TSS) is a rare, life-threatening complication. The incidence rate of TSS is very low in the plastic surgery field, especially after liposuction and fat transfer. Case presentation A 23-year-old female patient was transferred to our emergency department from an aesthetic clinic with sepsis shock features after received liposuction and fat transfer. The patient underwent TSS, disseminated intravascular coagulation(DIC), multiple organ dysfunction syndrome (MODS), symmetrical peripheral gangrene (SPG), and necrotizing soft tissue infection of the buttocks in the next 10 days. Authors used a series of debridement and reconstructive surgery including vacuum sealing drainage (VSD) treatment, artificial dermis grafts,split-thickness skin grafts, amputation surgeries when her vital signs were stable. The patient experienced desquamation of the hand on the 26th day. The skin grafts survived and the function of both fingers and toes recovered. She was discharged 2 months after admission and was in good health. Conclusion TSS is extremely rare in the field of liposuction and autologous fat transfer. The mortality rate of TSS is very high. Early diagnosis and operative treatment, as well as correction of systemic abnormalities, are the important keys to save a patient's life.

scholarly journals Pustules on the back possibly triggering toxic-shock syndrome

2019 ◽  
Vol 12 (6) ◽  
pp. e229610
Author(s):  
Hideharu Hagiya ◽  
Futoshi Nakagami ◽  
Yuki Minami ◽  
Hiroaki Terada
Keyword(s):  
Toxic Shock Syndrome ◽  
Gastrointestinal Symptoms ◽  
Sudden Onset ◽  
Multiple Organ ◽  
High Fever ◽  
Toxic Shock ◽  
Old Japanese ◽  
The Face ◽  
Organ Failures ◽  
Irregular Case

We herein describe an irregular case of toxic-shock syndrome (TSS). A previously healthy 28-year-old Japanese man developed a sudden-onset high fever. The patient was suffering from conjunctival hyperaemia, gastrointestinal symptoms such as vomiting and diarrhoea, and systemically diffused macular erythroderma. Further physical examination detected pustules on his back, which self-destructed over time. Laboratory revealed multiple organ failures. Subsequently, scalded skin on the face and desquamation in the limb extremities emerged by day 10, leading to the diagnosis of TSS, despite his stable circulatory dynamics through the course. Learning points for clinicians include that they should recall TSS as a possible disease concurrently causing high fever, systemic rash and multiple organ dysfunctions, even without being in a state of shock. The characteristic desquamations emerged in the limb extremities after hospitalisation were of help in diagnosing TSS.

scholarly journals Streptococcal necrotizing fasciitis with toxic shock syndrome and rapid fatal outcome

2015 ◽  
Vol 143 (7-8) ◽  
pp. 476-479 ◽  
Author(s):  
Miroslav Kojic ◽  
Dragan Mikic ◽  
Darko Nozic ◽  
Bojan Rakonjac
Keyword(s):  
Necrotizing Fasciitis ◽  
Toxic Shock Syndrome ◽  
Rapid Development ◽  
Fatal Outcome ◽  
Lower Leg ◽  
Multiple Organ ◽  
Deep Fascia ◽  
Rapid Progression ◽  
Toxic Shock ◽  
Serious Disease

Introduction. Streptococcal necrotizing fasciitis (NF) is a serious soft tissue infection with rapid progression of inflammatory process among superficial or deep fascia, systemic host response to infection leading to toxic shock syndrome (TSS), and multiple organ failure. Lethality is high. Case Outline. A 46-year-old male without co-morbidities was admitted to the Emergency Department with redness, swelling and pain on his right lower leg. He became sick two day s ea rlier with m alaise, chills and shivering. On admission he was hypotensive, anuric, with erythematous rash on his face, neck and chest, with acute ren al failure and elevated creatine phosphokinase level. During the next several hours, the changes on his right lower leg rapidly spread to the whole leg, followed by skin destruction and subcutaneo us bleeding, indicating NF. Aggressive antimicrobial, supportive and symptom atic therapy was initiated immediately and on the same evening surgical intervention was performed. Despite these measures, a rapid development of severe TSS, with lethal outcome, occurred in less than 40 hours after the admission. Stre ptococcus pyogenes (group A ?-hemolytic Streptococcus) was isolated from the throat, skin and tissue obtained duri ng the surgery. Conclusion. Necrotizing fasciitis is a very serious disease with unpre dictable course. For that reason doctors must devote a great deal of a ttention to early, i.e. timely diagnosis of this disease, whose treatment with a multid isciplinary approach is very important.

scholarly journals Successful Treatment of Streptococcal Toxic Shock Syndrome with Both Diffuse Peritonitis and Necrotizing Fasciitis

2018 ◽  
Vol 2018 ◽  
pp. 1-4
Author(s):  
Shuichi Sato ◽  
Masahiro Ito ◽  
Tsuyoshi Sakai ◽  
Anri Kaneta ◽  
Fumie Sato
Keyword(s):  
Mechanical Ventilation ◽  
Necrotizing Fasciitis ◽  
Toxic Shock Syndrome ◽  
Multiple Organ ◽  
Streptococcal Toxic Shock Syndrome ◽  
Diffuse Peritonitis ◽  
Multiple Organ Dysfunction ◽  
Toxic Shock ◽  
Life Threatening ◽  
Uncommon Case

Streptococcal toxic shock syndrome (STSS) is a life-threatening disease caused by infection of beta-hemolytic streptococci. Here, we report an uncommon case of STSS with both diffuse peritonitis and necrotizing fasciitis and summarize previous cases. The patient was diagnosed with STSS due to an infection of the soft tissue of the lower extremity after surgery for diffuse peritonitis. The general condition had rapidly deteriorated with multiple organ dysfunction. Immediate intensive care, including mechanical ventilation, hemodiafiltration, and repeated debridement, is indispensable for a favorable outcome.

scholarly journals A case report of streptococcal toxic shock syndrome caused by Streptococcus mitis in a healthy adult

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Xiang Chen ◽  
Ying Ying Gong ◽  
Li Zhang
Keyword(s):  
Septic Shock ◽  
Mortality Rate ◽  
Fluid Resuscitation ◽  
Toxic Shock Syndrome ◽  
Group A Streptococcus ◽  
Vital Signs ◽  
Streptococcal Toxic Shock Syndrome ◽  
Toxic Shock ◽  
Streptococcus Mitis ◽  
Aggressive Fluid Resuscitation

Abstract Background Streptococcal toxic shock syndrome (STSS) is an acute, multisystem and toxin-mediated disease that usually causes shock and multiple organ failure in the early stages of its clinical course. It is associated with a substantial increase in mortality rate. The disease has been associated with invasive group A Streptococcus and is rarely caused by Streptococcus mitis (S. mitis). In healthy adults, S. mitis is closely related to endocarditis but rarely related to STSS. Case presentation We report a case of STSS caused by S. mitis in a healthy 45-year-old woman. She presented with fever 14 h after surgery and with hypotension 24 h later, and she subsequently suffered from septic shock, low albumin, dysfunction of coagulation, acute kidney dysfunction, respiratory alkalosis and metabolic acidosis, acute respiratory distress syndrome and cellulitis of the incision. The diagnosis was obtained through clinical manifestation and blood culture examination. The patient was treated with aggressive fluid resuscitation, adequate antibiotics for a total of 4 weeks, respiratory support, and surgical debridement and drainage of the incision. She was discharged after her vital signs returned to normal and the incision healed on day 40 after surgery. Conclusions The diagnosis of STSS is often delayed or missed, which leads to a high mortality rate. It is possible to cure patients if the disease can be identified early and treated with aggressive fluid resuscitation, adequate antibiotics and control of the source of infection. Clinicians should consider the disease in the differential diagnosis of septic shock to prevent death.

scholarly journals The Management of Staphylococcal Toxic Shock Syndrome. A Case Report

2016 ◽  
Vol 2 (2) ◽  
pp. 85-88 ◽  
Author(s):  
Victoria Bîrluţiu ◽  
Ofelia Criştiu ◽  
Marius Baicu ◽  
Rareş Mircea Bîrluţiu
Keyword(s):  
Toxic Shock Syndrome ◽  
Treatment Plan ◽  
Diuretic Therapy ◽  
Local Treatment ◽  
Multiple Organ ◽  
Toxic Shock ◽  
Central Nervous System Damage ◽  
Organ Failures ◽  
Liver And Kidney ◽  
Staphylococcal Toxic Shock Syndrome

Abstract Staphylococcal toxic shock syndrome (TSS) is most frequently produced by TSS toxin-1 (TSST-1) and Staphylococcal enterotoxin B (SEB), and only rarely by enterotoxins A, C, D, E, and H. Various clinical pictures can occur depending on severity, patient age and immune status of the host. Severe forms, complicated by sepsis, are associated with a death rate of 50-60%. The case of a Caucasian female infant, aged seven weeks, hospitalized with a diffuse skin rash, characterized as allergodermia, who initially developed TSS with axillary intertrigo, is reported. TSS was confirmed according to 2011 CDC criteria, and blood cultures positive for Methicillin-sensitive Staphylococcus aureus (MSSA). Severe development occurred initial, including acidosis, consumption coagulopathy, multiple organ failures (MOF), including impaired liver and kidney function. Central nervous system damage was manifest by seizures. Clinical management included medical supervision by a multidisciplinary team of infectious diseases specialist and intensive care specialist, as well as the initiation of a complex treatment plan to correct hydro electrolytic imbalances and acidosis. This treatment included antibiotic and antifungal therapy, diuretic therapy, immunoglobulins, and local treatment similar to a patient with burns to prevent superinfection of skin and mucous membranes lesions. There was a favourable response to the treatment with resolution of the illness.

Probable Toxic Shock Syndrome Without Shock and Multisystem Involvement

PEDIATRICS ◽  
1982 ◽  
Vol 70 (2) ◽  
pp. 279-281
Author(s):  
James W. Bass ◽  
Lewis B. Harden ◽  
John H. Peixotto
Keyword(s):  
Staphylococcus Aureus ◽  
Abdominal Pain ◽  
Toxic Shock Syndrome ◽  
Multiple Organ ◽  
Organ System ◽  
Organ Injury ◽  
Conjunctival Injection ◽  
Toxic Shock ◽  
Multisystem Involvement ◽  
Multiple Organ Injury

Three menstruating adolescents using tampons colonized with Staphylococcus aureus developed high fever, vomiting, diarrhea, and abdominal pain followed by conjunctival injection and a sunburn-like rash. Two girls had transient orthostatic hypotension but none developed shock or evidence of multiple organ injury. They are reported as having probable toxic shock syndrome without shock or multiple organ system involvement.

scholarly journals Staphylococcal toxic shock syndrome in a child. Case report

2021 ◽  
Vol 4 (3) ◽  
pp. 302-307
Author(s):  
G.S. Karpovich ◽  
◽  
I.V. Kuimova ◽  
E.I. Krasnova ◽  
D.S. Maramygin ◽  
...  
Keyword(s):  
Case Report ◽  
Toxic Shock Syndrome ◽  
Group A Streptococcus ◽  
Wound Care ◽  
Pathological Condition ◽  
Multiple Organ ◽  
Toxic Shock ◽  
Causative Agents ◽  
Focus Of Infection ◽  
Staphylococcal Toxic Shock Syndrome

Toxic shock syndrome (TSS) is a complex of symptoms that includes fever, exanthem, multiple organ dysfunction syndrome, and hypotension. The most common causative agents are S. aureus and group A Streptococcus. TSS is characterized by severe course and high mortality in the lack of specific complex treatment. This article addresses a case report of staphylococcal TSS in a 5-year-old girl. The primary focus of infection (infected right leg wound) and breakthrough factors (the lack of adequate wound care) resulted in the dissemination of causative agent and TSS development. Despite disease severity, early complex etiological (antibiotics) and pathogenically-oriented (infusions, corticosteroids) treatment improved the patient’s condition and promoted recovery. This case report illustrating the classic presentations of staphylococcal TSS in children is helpful for pediatricians in terms of awareness of this pathological condition. KEYWORDS: infectious diseases, staphylococcus aureus, toxic shock syndrome, cytokine storm, multiple organ failure syndrome, pediatrics. FOR CITATION: Karpovich G.S., Kuimova I.V., Krasnova E.I. et al. Staphylococcal toxic shock syndrome in a child. Case report. Russian Journal of Woman and Child Health. 2021;4(3):302–307 (in Russ.). DOI: 10.32364/2618-8430-2021-4-3-302-307.

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